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Pharmacogenetics–Based Preliminary Algorithm to Predict the Incidence of Infection in Patients Receiving Cytotoxic Chemotherapy for Hematological Malignancies: A Discovery Cohort

Autor: Matias F. Martinez, Enzo Alveal, Tomas G. Soto, Eva I. Bustamante, Fernanda Ávila, Shrikant I. Bangdiwala, Ivonne Flores, Claudia Monterrosa, Ricardo Morales, Nelson M. Varela, Alison E. Fohner, Luis A. Quiñones

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

Introduction: Infections in hematological cancer patients are common and usually life-threatening; avoiding them could decrease morbidity, mortality, and cost. Genes associated with antineoplastics’ pharmacokinetics or with the immune/inflammatory

Externí odkaz: https://doaj.org/article/e82e7a05bc91402cb0531f36cfc3bc95

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IL-6 −572C>G and CARD8 304T>A Genetic Polymorphisms are Associated with the Absolute Neutrophil Count in Patients with Hematological Malignancies Under Chemotherapy: An Application of Multilevel Models to a Preliminary Pharmacogenetic Study

Autor: Shrikant I. Bangdiwala, Ivonne Flores, Tomas G. Soto, Ricardo Morales, Enzo Alveal, Nelson Varela, Eva Bustamante, Matías F. Martínez, Claudia Andrea Araya Benavides, Fernanda Avila, Luis A. Quiñones

Publikováno v: Pharmacogenomics and Personalized Medicine

Matias F Martinez,1,2 Enzo Alveal,1 Tomas G Soto,1,3 Eva I Bustamante,4 Fernanda Ávila,5 Shrikant I Bangdiwala,6,7 Ivonne Flores,4 Claudia Benavides,4 Ricardo Morales,4 Nelson M Varela,1,2 Luis A Quiñones1,2 1Laboratory of Chemical Carcinogenesis a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec28b3e1a07e1e3e41117a8f9f684fd
https://doi.org/10.2147/pgpm.s261208

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