Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Enxhi, Shaba"'
Autor:
Luca Ponzone, Valentina Audrito, Claudia Landi, Enrico Moiso, Chiara Levra Levron, Sara Ferrua, Aurora Savino, Nicoletta Vitale, Massimiliano Gasparrini, Lidia Avalle, Lorenza Vantaggiato, Enxhi Shaba, Beatrice Tassone, Stefania Saoncella, Francesca Orso, Daniele Viavattene, Eleonora Marina, Irene Fiorilla, Giulia Burrone, Youssef Abili, Fiorella Altruda, Luca Bini, Silvia Deaglio, Paola Defilippi, Alessio Menga, Valeria Poli, Paolo Ettore Porporato, Paolo Provero, Nadia Raffaelli, Chiara Riganti, Daniela Taverna, Federica Cavallo, Enzo Calautti
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background The main drawback of BRAF/MEK inhibitors (BRAF/MEKi)-based targeted therapy in the management of BRAF-mutated cutaneous metastatic melanoma (MM) is the development of therapeutic resistance. We aimed to assess in this context the
Externí odkaz:
https://doaj.org/article/18874da7221f495c92ee85e23df7d535
Autor:
Enxhi Shaba, Claudia Landi, Carlotta Marzocchi, Lorenza Vantaggiato, Luca Bini, Claudia Ricci, Silvia Cantara
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11463 (2023)
The genome sequencing of the tardigrade Ramazzottius varieornatus revealed a unique nucleosome-binding protein named damage suppressor (Dsup), which was discovered to be crucial for the extraordinary abilities of tardigrades in surviving extreme stre
Externí odkaz:
https://doaj.org/article/70efeb1bcb864234a46ac2ce8704be2a
Autor:
Lorenza Vantaggiato, Enxhi Shaba, Paolo Cameli, Laura Bergantini, Miriana d’Alessandro, Alfonso Carleo, Giusy Montuori, Luca Bini, Elena Bargagli, Claudia Landi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 925 (2023)
Idiopathic pulmonary fibrosis (IPF) is a form of chronic and irreversible fibrosing interstitial pneumonia of unknown etiology. Although antifibrotic treatments have shown a reduction of lung function decline and a slow disease progression, IPF is ch
Externí odkaz:
https://doaj.org/article/956d449db9224911bb4fec9e2c67c24e
Autor:
Lorenza Vantaggiato, Enxhi Shaba, Alfonso Carleo, Daiana Bezzini, Giovanna Pannuzzo, Alice Luddi, Paola Piomboni, Luca Bini, Laura Bianchi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13537 (2022)
Krabbe disease (KD) is a rare autosomal recessive disorder caused by mutations in the galactocerebrosidase gene (GALC). Defective GALC causes aberrant metabolism of galactolipids present almost exclusively in myelin, with consequent demyelinization a
Externí odkaz:
https://doaj.org/article/1fa18d3e2de647f6bd1a36565823574a
Autor:
Enxhi Shaba, Lorenza Vantaggiato, Laura Governini, Alesandro Haxhiu, Guido Sebastiani, Daniela Fignani, Giuseppina Emanuela Grieco, Laura Bergantini, Luca Bini, Claudia Landi
Publikováno v:
Proteomes, Vol 10, Iss 2, p 12 (2022)
In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological processes is overcome and system biology approaches have been providing new perspectives to see through. In this context, extracellular vesicles (EVs) are offeri
Externí odkaz:
https://doaj.org/article/ea871ce96df941ee81c5b3072a6e2b8c
Autor:
Lorenza Vantaggiato, Paolo Cameli, Laura Bergantini, Miriana d’Alessandro, Enxhi Shaba, Alfonso Carleo, Fabrizio Di Giuseppe, Stefania Angelucci, Guido Sebastiani, Francesco Dotta, Luca Bini, Elena Bargagli, Claudia Landi
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 761 (2022)
Severe eosinophilic asthma is characterized by chronic airway inflammation, oxidative stress, and elevated proinflammatory cytokines, especially IL-5. Mepolizumab and benralizumab are both humanized IgG antibodies directed against IL-5 signaling, dir
Externí odkaz:
https://doaj.org/article/ead7b97d4bcf443ca312b7992314473b
Autor:
Rosetta Ponchia, Annunziata Bruno, Asia Renzi, Claudia Landi, Enxhi Shaba, Francesca Paola Luongo, Alesandro Haxhiu, Paolo Giovanni Artini, Alice Luddi, Laura Governini, Paola Piomboni
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 10 (2021)
Despite its widespread use, sperm cryopreservation induces serious detrimental alterations in sperm function; indeed, it is commonly associated with decreased sperm viability and motility, and DNA fragmentation. Mechanisms of human sperm cryodamage a
Externí odkaz:
https://doaj.org/article/aad6ce6ffa2c47c09af50b9d59162a2b
Autor:
Claudia Landi, Giulia Liberatori, Pietro Cotugno, Lucrezia Sturba, Maria Luisa Vannuccini, Federica Massari, Daniela Valeria Miniero, Angelo Tursi, Enxhi Shaba, Peter A. Behnisch, Alfonso Carleo, Fabrizio Di Giuseppe, Stefania Angelucci, Luca Bini, Ilaria Corsi
Publikováno v:
Toxics, Vol 10, Iss 1, p 9 (2021)
A topsoil sample obtained from a highly industrialized area (Taranto, Italy) was tested on the DR-CALUX® cell line and the exposed cells processed with proteomic and bioinformatics analyses. The presence of polyhalogenated compounds in the topsoil e
Externí odkaz:
https://doaj.org/article/465617fc7a764686a2ef025963588927
Autor:
Tommaso Montecchi, Enxhi Shaba, Domiziana De Tommaso, Fabrizio Di Giuseppe, Stefania Angelucci, Luca Bini, Claudia Landi, Cosima Tatiana Baldari, Cristina Ulivieri
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 7933 (2021)
Reactive astrocytes are a hallmark of neurodegenerative disease including multiple sclerosis. It is widely accepted that astrocytes may adopt alternative phenotypes depending on a combination of environmental cues and intrinsic features in a highly p
Externí odkaz:
https://doaj.org/article/6a5ff059b5a34705bdf834a23fb02439
Autor:
Enxhi Shaba, Claudia Landi, Alfonso Carleo, Lorenza Vantaggiato, Eugenio Paccagnini, Mariangela Gentile, Laura Bianchi, Pietro Lupetti, Elena Bargagli, Antje Prasse, Luca Bini
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5696 (2021)
In the longtime challenge of identifying specific, easily detectable and reliable biomarkers of IPF, BALF proteomics is providing interesting new insights into its pathogenesis. To the best of our knowledge, the present study is the first shotgun pro
Externí odkaz:
https://doaj.org/article/997a54797f5445b897b9f8a2739cac30