Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Enver Cagri Izgu"'
Autor:
Tushar Aggarwal, Alyssa Bellomo, Emily R. Stevenson, Julia Herbert, Debra L. Laskin, Andrew J. Gow, Enver Cagri Izgu
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103268- (2024)
Summary: Detection of nitrative stress is crucial to understanding redox signaling and pathophysiology. Dysregulated nitrative stress, which generates high levels of peroxynitrite, can damage lipid membranes and cause activation of proinflammatory pa
Externí odkaz:
https://doaj.org/article/ada23d3893a640f2be0b4ca150003d81
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103169- (2024)
Summary: Sensing is a critical function of artificial cells; however, this is challenging to realize using bottom-up approaches. Here, we present a protocol for building protocell membranes that sense cues important for redox biochemistry and signali
Externí odkaz:
https://doaj.org/article/063cbcfce36a4ab398b25c2beecd8404
Autor:
Huseyin Erguven, Liming Wang, Bryan Gutierrez, Andrew H. Beaven, Alexander J. Sodt, Enver Cagri Izgu
Publikováno v:
JACS Au, Vol 4, Iss 5, Pp 1841-1853 (2024)
Externí odkaz:
https://doaj.org/article/6a939c016aca4bddadbd6f4fb3494f08
Autor:
Bryan Gutierrez, Tushar Aggarwal, Huseyin Erguven, M. Rhia L. Stone, Changjiang Guo, Alyssa Bellomo, Elena Abramova, Emily R. Stevenson, Debra L. Laskin, Andrew J. Gow, Enver Cagri Izgu
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108567- (2023)
Summary: Lipid membranes and lipid-rich organelles are targets of peroxynitrite (ONOO−), a highly reactive species generated under nitrative stress. We report a membrane-localized phospholipid (DPPC-TC-ONOO–) that allows the detection of ONOO−
Externí odkaz:
https://doaj.org/article/7d5e3267fe8549069245b5c1f20f2a6e
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 11, Pp 100282- (2022)
In the yeast Saccharomyces cerevisiae, the PAH1-encoded Mg2+-dependent phosphatidate (PA) phosphatase Pah1 regulates the bifurcation of PA to diacylglycerol (DAG) for triacylglycerol (TAG) synthesis and to CDP-DAG for phospholipid synthesis. Pah1 fun
Externí odkaz:
https://doaj.org/article/241ef5e46fca4421979dd020ef0462f7
Autor:
Tushar Aggarwal, William A. Hansen, Jonathan Hong, Abir Ganguly, Darrin M. York, Sagar D. Khare, Enver Cagri Izgu
Publikováno v:
ACS Chem Biol
DNA polymerases have evolved to feature a highly conserved activity across the tree of life: formation of, without exception, phosphodiester linkages that create the repeating sugarphosphate backbone of DNA. Can this linkage selectivity observed in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed41e77bdffe9225d677f36c233f73ba
https://pubmed.ncbi.nlm.nih.gov/35776893
https://pubmed.ncbi.nlm.nih.gov/35776893
Lipid environments can be damaged by peroxynitrite (ONOO−), a highly reactive redox species generated under nitrosative stress conditions. Strategies to investigate ONOO−via light microscopy are limited, and amphiphilic sensors capable of detecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968372a6c3789831ae9ca4a16b5c9bbd
https://doi.org/10.1101/2022.06.22.497268
https://doi.org/10.1101/2022.06.22.497268
Publikováno v:
ACS Appl Mater Interfaces
Realization of robust and facile surface functionalization processes is critical to biomaterials and biotechnology yet remains a challenge. Here, we report a new chemical approach that enables operationally simple and site-specific surface functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7bd9921befe5db492562b4b02a9387
https://doi.org/10.1021/acsami.0c19396
https://doi.org/10.1021/acsami.0c19396
Intercellular microRNA (miRNA)-based communication has been implicated in a wide array of functional and dysfunctional biological processes. This has raised attention to the potential use of miRNAs as biomarkers for disease diagnosis and prognosis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b6c9c85437344252edf76157289884
https://doi.org/10.1101/2022.01.17.476684
https://doi.org/10.1101/2022.01.17.476684
Publikováno v:
Bioorg Med Chem
MicroRNA (miRNA)-based intercellular communication has been implicated in many functional and dysfunctional biological processes. This has raised interest in the potential use of miRNAs as biomarkers for diagnosis and prognosis. Though the list of cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebb5be56bfc284958213d74db01ed52
https://doi.org/10.2139/ssrn.4067278
https://doi.org/10.2139/ssrn.4067278