Metagenomic Survey of Potential Symbiotic Bacteria and Polyketide Synthase Genes in an Indonesian Marine Sponge

Autor: Nia M. Kurnia, Agustinus R. Uria, Yudi Kusnadi, Lidia Dinawati, Dewi S. Zilda, Tri A. Hadi, Siswa Setyahadi, Feliatra Felix

Publikováno v: Hayati Journal of Biosciences, Vol 24, Iss 1, Pp 6-15 (2017)

There has been emerging evidence that the bacteria associated with marine sponges are the key producers of many complex bioactive compounds. The as-yet uncultured candidate bacterial genus “Candidatus Entotheonella” of the marine sponge Theonella

Externí odkaz: https://doaj.org/article/509680b7110249fca9d23700f39d44aa

New genomic insights into 'Entotheonella' symbionts in Theonella swinhoei: mixotrophy, anaerobic adaptation, resilience, and interaction

Autor: Fang Liu, Jinlong Li, Guofang Feng, Zhiyong Li

Publikováno v: Frontiers in Microbiology, Vol 7 (2016)

Entotheonella (phylum Tectomicrobia) is a filamentous symbiont that produces almost all known bioactive compounds derived from the Lithistida sponge Theonella swinhoei. In contrast to the comprehensive knowledge of its secondary metabolism, knowledge

Externí odkaz: https://doaj.org/article/5cd32d17843042c487dde789a942f6f1

The swinholide biosynthesis gene cluster from a terrestrial cyanobacterium, Nostoc sp. strain UHCC 0450

Autor: David P. Fewer, Anu Humisto, Liwei Liu, João Paulo Machado, Hao Wang, Perttu Permi, Agostinho Antunes, Jouni Jokela, Matti Wahlsten, Kaarina Sivonen

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Applied and Environmental Microbiology

Swinholides are 42-carbon ring polyketides with a 2-fold axis of symmetry. They are potent cytotoxins that disrupt the actin cytoskeleton. Swinholides were discovered from the marine sponge Theonella sp. and were long suspected to be produced by symb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5a9e7d4141651b972da4642bb57996

Specialized microbiome of the cave-dwelling sponge Plakina kanaky (Porifera, Homoscleromorpha)

Autor: Marcela Villegas-Plazas, Howard Junca, Thierry Perez, César Ruiz, Olivier P. Thomas

Publikováno v: FEMS Microbiology Ecology
FEMS Microbiology Ecology, 2020, 96 (4), pp.fiaa043. ⟨10.1093/femsec/fiaa043⟩
FEMS Microbiology Ecology, Wiley-Blackwell, 2020, 96 (4), pp.fiaa043. ⟨10.1093/femsec/fiaa043⟩

The recent description of the polychromatic sponge Plakina kanaky revealed original microsymbionts, with some morphotypes recorded for the first time in Homoscleromorpha and others never before observed in other sponge groups. Illumina 16S amplicon s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d61234bec51f24567237a54fd593540
https://pubmed.ncbi.nlm.nih.gov/32175570

Biosynthetic Insights of Calyculin- and Misakinolide-Type Compounds in 'Candidatus Entotheonella sp.'

Autor: Toshiyuki Wakimoto, Agustinus Robert Uria, Jörn Piel

Microbial symbionts are recognized as the important sources of numerous sponge-derived metabolites with potent biological activities. The limitation to cultivate the majority of potential symbionts has hampered attempts to explore and exploit their n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6e8363fd869e4b7b62c95d120a81693
https://doi.org/10.1016/bs.mie.2018.02.017