4-Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Acetylcholinesterase.

Autor: Lovins AR; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Miller KA; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Buck AK; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Ensey DS; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Homoelle RK; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Murtha MC; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Ward NA; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Shanahan LA; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Gutti G; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University, Columbus, Ohio 43210, United States., Shriwas P; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University, Columbus, Ohio 43210, United States., McElroy CA; Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University, Columbus, Ohio 43210, United States., Callam CS; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States., Hadad CM; Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States.

Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2024 May 01; Vol. 15 (9), pp. 1813-1827. Date of Electronic Publication: 2024 Apr 15.