Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Enrique Sanchez-Lemus"'
Publikováno v:
Neuropharmacology. 79:249-261
Sartans (Angiotensin II AT1 Receptor Blockers, ARBs) are powerful neuroprotective agents in vivo and protect against IL-1β neurotoxicity in vitro. The purpose of this research was to determine the extent of sartan neuroprotection against glutamate e
Autor:
Enrique Sanchez-Lemus, Aviva J. Symes, Juan M. Saavedra, Trevor T. Logan, Alexandra K. Yaszemski, Sonia Villapol
Publikováno v:
Neuropsychopharmacology. 37:2817-2829
Traumatic brain injury (TBI) results in complex pathological reactions, the initial lesion worsened by secondary inflammation and edema. Angiotensin II (Ang II) is produced in the brain and Ang II receptor type 1 (AT₁R) overstimulation produces vas
Publikováno v:
Behavioural Brain Research. 232:84-92
Centrally acting Angiotensin II AT(1) receptor blockers (ARBs) protect from stress-induced disorders and decrease anxiety in a model of inflammatory stress, the systemic injection of bacterial endotoxin lipopolysaccharide (LPS). In order to better un
Publikováno v:
Journal of Hypertension. 30:87-96
Angiotensin II type 1 receptor (AT1) blockers (ARBs) reduce the bacterial endotoxin lipopolysaccharide (LPS)-induced innate immune response in human circulating monocytes expressing few AT1. To clarify the mechanisms of anti-inflammatory effects of A
Autor:
Ignacio M. Larrayoz, Jaroslav Pavel, Enrique Sanchez-Lemus, Julius Benicky, Juan M. Saavedra, Tao Pang
Publikováno v:
Journal of Hypertension. 27:2365-2376
Inhibition of angiotensin II receptor type 1 (AT1) reduces chronic inflammation associated with hypertension. We asked whether AT1 receptor inhibition would reduce the innate inflammatory response induced by bacterial lipopolysaccharide (LPS).We used
Autor:
Tsuyoshi Nishioku, Enrique Sanchez-Lemus, Juan M. Saavedra, Martina Baliova, Julius Benicky, Ignacio M. Larrayoz, Jin Zhou, Jaroslav Pavel
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 296:R1376-R1384
ANG II AT1 receptor blockade reduces inflammation in hypertension. To determine whether ANG II AT1 receptor blockers (ARBs) influence the innate immune inflammatory response in normotensive rats, we studied rat plasma and spleen after a 3-day subcuta
Autor:
Tsuyoshi Nishioku, Yuki Murakami, Jaroslav Pavel, Enrique Sanchez-Lemus, Juan M. Saavedra, Ignacio M. Larrayoz-Roldan, Armen J. Moughamian
Publikováno v:
Endocrinology. 149:5177-5188
Peripheral administration of bacterial endotoxin [lipopolysaccharide (LPS)] to rodents produces an innate immune response and hypothalamic-pituitary-adrenal axis stimulation. Renin-angiotensin-aldosterone system inhibition by angiotensin II AT1 recep
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 9, Iss 1, p 102 (2012)
Journal of Neuroinflammation, Vol 9, Iss 1, p 102 (2012)
Background Blockade of angiotensin II type 1 (AT1) receptors ameliorates brain inflammation, and reduces excessive brain interleukin-1 beta (IL-1β) production and release from cortical microglia. The aim of this study was to determine whether, in ad
Autor:
De-Maw Chuang, Yan Leng, Juan M. Saavedra, Tao Pang, Enrique Sanchez-Lemus, Masaru Honda, Juan Wang, Julius Benicky, Martina Orecna
Brain inflammation has a critical role in the pathophysiology of brain diseases of high prevalence and economic impact, such as major depression, schizophrenia, post-traumatic stress disorder, Parkinson's and Alzheimer's disease, and traumatic brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2a96598bd6680775d886fe0fab0b80
https://europepmc.org/articles/PMC3055735/
https://europepmc.org/articles/PMC3055735/
Publikováno v:
Psychoneuroendocrinology. 36(1)
Poor adaptation to stress, alterations in cerebrovascular function and excessive brain inflammation play critical roles in the pathophysiology of many psychiatric and neurological disorders such as major depression, schizophrenia, post traumatic stre