Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Enrique Gómez Lahoz"'
Autor:
James W. Horner, Enrique Gómez Lahoz, Stephen J. Elledge, Nanette J. Liégeois, Adam Silverman, Jeffrey A. Engelman, Pumin Zhang, Ronald M. Burde, Martine F. Roussel, Charles J. Sherr, Ronald A. DePinho
Publikováno v:
Europe PubMed Central
This study examines in vivo the role and functional interrelationships of components regulating exit from the G1 resting phase into the DNA synthetic (S) phase of the cell cycle. Our approach made use of several key experimental attributes of the dev
Publikováno v:
Science (New York, N.Y.). 267(5195)
The cyclin-dependent kinase 4 (CDK4) regulates progression through the G1 phase of the cell cycle. The activity of CDK4 is controlled by the opposing effects of the D-type cyclin, an activating subunit, and p16INK4, an inhibitory subunit. Ectopic exp