Environmental and genetic factors support the dissociation between α-synuclein aggregation and toxicity

Autor: Ira Milosevic, Ellen Gerhardt, Caterina Masaracchia, Enrique Abad Gonzalez, Raquel Ramos Pinho, Giulia Rossetti, Claudio O. Fernández, Anna Villar-Piqué, Markus Zweckstetter, Anita Carija, Salvador Ventura, Debora Foguel, Paolo Carloni, Éva M. Szegö, Tomás Lopes da Fonseca, Luis Fonseca-Ornelas, Ricardo Sant'Anna, Tiago F. Outeiro

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America 113(42), E6506-E6515 (2016). doi:10.1073/pnas.1606791113
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Synucleinopathies are a group of progressive disorders characterized by the abnormal aggregation and accumulation of α-synuclein (aSyn), an abundant neuronal protein that can adopt different conformations and biological properties. Recently, aSyn pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b082eb3f1b773cd6384717581e19dfa
https://hdl.handle.net/11858/00-001M-0000-002B-96CD-721.11116/0000-0002-4B71-B21.11116/0000-0002-4B72-A