Výsledky vyhledávání - "Enrique, de Alava"

Akademický článek

ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Abstract Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising as in some other cancer types due to intra-tumor heterogeneity and

Externí odkaz: https://doaj.org/article/aeb35d7698f54300a9d32846913690b0

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Akademický článek

Uterine sarcomas: clinical practice guidelines for diagnosis, treatment, and follow-up, by Spanish group for research on sarcomas (GEIS)

Autor: Jose Alejandro Pérez-Fidalgo, Eugenia Ortega, Jordi Ponce, Andres Redondo, Isabel Sevilla, Claudia Valverde, Josep Isern Verdum, Enrique de Alava, Mar Galera López, Gloria Marquina, Ana Sebio

Publikováno v: Therapeutic Advances in Medical Oncology, Vol 15 (2023)

Uterine sarcomas are very infrequent and heterogeneous entities. Due to its rarity, pathological diagnosis, surgical management, and systemic treatment are challenging. Treatment decision process in these tumors should be taken in a multidisciplinary

Externí odkaz: https://doaj.org/article/aaf4e864ae8949438bd7f63f170a8840

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Akademický článek

Integrating digital pathology with transcriptomic and epigenomic tools for predicting metastatic uterine tumor aggressiveness

Autor: Giorgia Sonzini, Sofia Granados-Aparici, Sabina Sanegre, Angel Diaz-Lagares, Juan Diaz-Martin, Carlos de Andrea, Núria Eritja, Aida Bao-Caamano, Nicolás Costa-Fraga, David García-Ros, Carmen Salguero-Aranda, Ben Davidson, Rafael López-López, Ignacio Melero, Samuel Navarro, Santiago Ramon y Cajal, Enrique de Alava, Xavier Matias-Guiu, Rosa Noguera

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

The incidence of new cancer cases is expected to increase significantly in the future, posing a worldwide problem. In this regard, precision oncology and its diagnostic tools are essential for developing personalized cancer treatments. Digital pathol

Externí odkaz: https://doaj.org/article/1debe2f1f3eb466fb9188e4c9d95f9d3

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Akademický článek

Characterizing the Invasive Tumor Front of Aggressive Uterine Adenocarcinoma and Leiomyosarcoma

Autor: Sabina Sanegre, Núria Eritja, Carlos de Andrea, Juan Diaz-Martin, Ángel Diaz-Lagares, María Amalia Jácome, Carmen Salguero-Aranda, David García Ros, Ben Davidson, Rafel Lopez, Ignacio Melero, Samuel Navarro, Santiago Ramon y Cajal, Enrique de Alava, Xavier Matias-Guiu, Rosa Noguera

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

The invasive tumor front (the tumor–host interface) is vitally important in malignant cell progression and metastasis. Tumor cell interactions with resident and infiltrating host cells and with the surrounding extracellular matrix and secreted fact

Externí odkaz: https://doaj.org/article/743805c8e0f34b5ba6114838c5cfc6a8

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Akademický článek

Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Background Sarcomas exhibit low expression of factors related to immune response, which could explain the modest activity of PD-1 inhibitors. A potential strategy to convert a cold into an inflamed microenvironment lies on a combination therapy. As t

Externí odkaz: https://doaj.org/article/ba0c92285ab347e788e84cf5c6815dde

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