Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Enrique, García Hernández"'
Autor:
Norma A. Valdez‑Cruz, Diego Rosiles-Becerril, Constanza E. Martínez-Olivares, Enrique García‑Hernández, Laura Cobos-Marín, Daniel Garzón, Francisco E. López-Salas, Guadalupe Zavala, Axel Luviano, Alejandro Olvera, Alejandro Alagón, Octavio T. Ramírez, Mauricio A. Trujillo‑Roldán
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Background Developing effective vaccines against SARS-CoV-2 that consider manufacturing limitations, equitable access, and acceptance is necessary for developing platforms to produce antigens that can be efficiently presented for generating
Externí odkaz:
https://doaj.org/article/e13a32445db2407eaf766e0d1f636291
Autor:
Diana L. Prado-Romero, Fernanda I. Saldívar-González, Iván López-Mata, Pedro A. Laurel-García, Adrián Durán-Vargas, Enrique García-Hernández, Norberto Sánchez-Cruz, José L. Medina-Franco
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 775 (2024)
Designing and developing inhibitors against the epigenetic target DNA methyltransferase (DNMT) is an attractive strategy in epigenetic drug discovery. DNMT1 is one of the epigenetic enzymes with significant clinical relevance. Structure-based de novo
Externí odkaz:
https://doaj.org/article/bc2952031d3843e5ac94fd48ed862e5a
Autor:
Sara Restrepo-Pineda, Diego Rosiles-Becerril, Angélica B. Vargas-Castillo, Luis P. Ávila-Barrientos, Axel Luviano, Nuria Sánchez-Puig, Enrique García-Hernández, Nestor O. Pérez, Mauricio A. Trujillo-Roldán, Norma A. Valdez-Cruz
Publikováno v:
Electronic Journal of Biotechnology, Vol 59, Iss , Pp 94-106 (2022)
Background: The temperature upshift has been widely used as an induction system to produce recombinant proteins (RPs). However, thermoinduction could affect bacterial metabolism, RP production, and RP aggregation. Understanding the structure and func
Externí odkaz:
https://doaj.org/article/25c75a7d5a5141f4a70b07f15ae552be
Autor:
Luis Fernando Cofas-Vargas, Paola Mendoza-Espinosa, Luis Pablo Avila-Barrientos, Diego Prada-Gracia, Héctor Riveros-Rosas, Enrique García-Hernández
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
In addition to playing a central role in the mitochondria as the main producer of ATP, FOF1-ATP synthase performs diverse key regulatory functions in the cell membrane. Its malfunction has been linked to a growing number of human diseases, including
Externí odkaz:
https://doaj.org/article/17d8a8ce8039438493a490a74edf5cf5
Autor:
Norma A. Valdez-Cruz, Enrique García-Hernández, Clara Espitia, Laura Cobos-Marín, Claudia Altamirano, Carlos G. Bando-Campos, Luis F. Cofas-Vargas, Enrique W. Coronado-Aceves, Ricardo A. González-Hernández, Pablo Hernández-Peralta, Daniel Juárez-López, Paola A. Ortega-Portilla, Sara Restrepo-Pineda, Patricio Zelada-Cordero, Mauricio A. Trujillo-Roldán
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-32 (2021)
Abstract SARS-CoV-2 is a novel β-coronavirus that caused the COVID-19 pandemic disease, which spread rapidly, infecting more than 134 million people, and killing almost 2.9 million thus far. Based on the urgent need for therapeutic and prophylactic
Externí odkaz:
https://doaj.org/article/7b60248d60cb49b694218f5a886eee87
Autor:
Luis Pablo Avila-Barrientos, Luis Fernando Cofas-Vargas, Guillermin Agüero-Chapin, Enrique Hernández-García, Sergio Ruiz-Carmona, Norma A. Valdez-Cruz, Mauricio Trujillo-Roldán, Joachim Weber, Yasser B. Ruiz-Blanco, Xavier Barril, Enrique García-Hernández
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 557 (2022)
With the uncontrolled growth of multidrug-resistant bacteria, there is an urgent need to search for new therapeutic targets, to develop drugs with novel modes of bactericidal action. FoF1-ATP synthase plays a crucial role in bacterial bioenergetic pr
Externí odkaz:
https://doaj.org/article/db2affc2047141aab1e191d534aab100
Autor:
Yasser B. Ruiz-Blanco, Guillermin Agüero-Chapin, Enrique García-Hernández, Orlando Álvarez, Agostinho Antunes, James Green
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Computational prediction of protein function constitutes one of the more complex problems in Bioinformatics, because of the diversity of functions and mechanisms in that proteins exert in nature. This issue is reinforced especiall
Externí odkaz:
https://doaj.org/article/ff0a29516e424b4d854ec40d0e209808
Autor:
Gustavo Titaux-Delgado, Andrea Estefanía Lopez-Giraldo, Elisa Carrillo, Luis Fernando Cofas-Vargas, Luis Enrique Carranza, Estuardo López-Vera, Enrique García-Hernández, Federico del Rio-Portilla
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1871:140906
Autor:
Enrique García-Hernández, Guillermin Agüero-Chapin, Yasser Ruiz-Blanco, Luis Ávila-Barrientos, Enrique Hernández-García, Agostinho Antunes
Publikováno v:
Proceedings of MOL2NET'22, Conference on Molecular, Biomedical & Computational Sciences and Engineering, 8th ed. - MOL2NET: FROM MOLECULES TO NETWORKS.
Autor:
Guillermin Agüero-Chapin, Yasser B Ruiz-Blanco, Luis Pablo Avila-Barrientos, Enrique García-Hernández, Enrique Hernández-García, Agostinho Antunes
Publikováno v:
FEBS Letters. 595:183-194
Enzyme subunit interfaces have remarkable potential in drug design as both target and scaffold for their own inhibitors. We show an evolution-driven strategy for the de novo design of peptide inhibitors targeting interfaces of the Escherichia coli Fo