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Autor:
Guerra-Assunção José, Enright Anton J
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 218 (2012)
Abstract Background In animals, microRNAs (miRNA) are important genetic regulators. Animal miRNAs appear to have expanded in conjunction with an escalation in complexity during early bilaterian evolution. Their small size and high-degree of similarit
Externí odkaz:
https://doaj.org/article/c2de48067f6b44ae84271a57b5a0edf7
Publikováno v:
BMC Evolutionary Biology, Vol 11, Iss 1, p 334 (2011)
Abstract Background Leishmania META1 has for long been a candidate molecule for involvement in virulence: META1 transcript and protein are up-regulated in metacyclic Leishmania. Yet, how META1 contributes to virulence remains unclear. We sought insig
Externí odkaz:
https://doaj.org/article/82abf93bf54045eba33d40662fc1a7c6
Autor:
Thornton Claire M, Piipari Matias, Pett Mark R, Muralidhar Balaji, Palmer Roger D, van Dongen Stijn, Saini Harpreet K, Murray Matthew J, Nicholson James C, Enright Anton J, Coleman Nicholas
Publikováno v:
Molecular Cancer, Vol 9, Iss 1, p 290 (2010)
Abstract Background We hypothesised that differences in microRNA expression profiles contribute to the contrasting natural history and clinical outcome of the two most common types of malignant germ cell tumour (GCT), yolk sac tumours (YSTs) and germ
Externí odkaz:
https://doaj.org/article/d6df6669e4b446bd9f8f81fc4632baed
Autor:
Guerra-Assunção José, Enright Anton J
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 133 (2010)
Abstract Background A large effort to discover microRNAs (miRNAs) has been under way. Currently miRBase is their primary repository, providing annotations of primary sequences, precursors and probable genomic loci. In many cases miRNAs are identical
Externí odkaz:
https://doaj.org/article/9712480e099245cbabb0d5f41ee26918
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 175 (2010)
Abstract Background RNA inhibition by siRNAs is a frequently used approach to identify genes required for specific biological processes. However RNAi screening using siRNAs is hampered by non-specific or off target effects of the siRNAs, making it di
Externí odkaz:
https://doaj.org/article/1d9427f7095442a8923734562ee46af8
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 419 (2009)
Abstract Background Synapse formation and the development of neural networks are known to be controlled by a coordinated program of mRNA synthesis. microRNAs are now recognized to be important regulators of mRNA translation and stability in a wide va
Externí odkaz:
https://doaj.org/article/7867a295ceea411ca5eead0447cfbb1e
Publikováno v:
BMC Genomics, Vol 9, Iss 1, p 564 (2008)
Abstract Background MicroRNAs (miRNAs) are important regulators of gene expression and have been implicated in development, differentiation and pathogenesis. Hundreds of miRNAs have been discovered in mammalian genomes. Approximately 50% of mammalian
Externí odkaz:
https://doaj.org/article/24497a3f059c414ebd138194495722fc
Autor:
Freilich Shiri, Goldovsky Leon, Kamburov Atanas, Kapazoglou Aliki, Kunin Victor, Enright Anton J, Tsaftaris Athanasios, Ouzounis Christos A
Publikováno v:
BMC Genomics, Vol 8, Iss 1, p 460 (2007)
Abstract Background Gene fusion detection – also known as the 'Rosetta Stone' method – involves the identification of fused composite genes in a set of reference genomes, which indicates potential interactions between its un-fused counterpart gen
Externí odkaz:
https://doaj.org/article/b4f6663fc0a84295882c915e93ba471f
Autor:
van Dongen, Stijn, Enright, Anton J.
We investigate two classes of transformations of cosine similarity and Pearson and Spearman correlations into metric distances, utilising the simple tool of metric-preserving functions. The first class puts anti-correlated objects maximally far apart
Externí odkaz:
http://arxiv.org/abs/1208.3145
