Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Enrico Selva"'
Autor:
Emiliana Corti, Francesco Parenti, Franca Castiglione, Paolo Candiani, Enrico Selva, Ameriga Lazzarini, Daniele Losi, Flavia Marinelli, Ismaela Ciciliato, Lucia Carrano, L. Gastaldo
Publikováno v:
Chemistry & Biology. 15(1):22-31
Summary Antibiotics blocking bacterial cell wall assembly (β-lactams and glycopeptides) are facing a challenge from the progressive spread of resistant pathogens. Lantibiotics are promising candidates to alleviate this problem. Microbisporicin, the
Publikováno v:
The Journal of Antibiotics. 60:447-454
An efficient method for protoplast generation for the uncommon actinomycete Planobispora rosea, the producer of the thiazolylpeptide antibiotic GE2270, was developed using a combination of hen egg white lysozyme and Streptomyces globisporus mutanolys
Autor:
Gianpaolo Candiani, Marina Feroggio, Emiliana Corti, Franca Castiglione, Daniele Losi, Ismaela Ciciliato, Ameriga Lazzarini, Flavia Marinelli, Linda Cavaletti, Enrico Selva, Lucia Carrano
Publikováno v:
Biochemistry. 46:5884-5895
Important classes of antibiotics acting on bacterial cell wall biosynthesis, such as beta-lactams and glycopeptides, are used extensively in therapy and are now faced with a challenge because of the progressive spread of resistant pathogens. A discov
Autor:
Emiliana Corti, Claudio O. Gualerzi, Monica Abbondi, Attilio Fabbretti, Daniele Losi, Marina Feroggio, Stefano Donadio, Ameriga Lazzarini, Alessandro Maio, Letizia Brandi, Marazzi Alessandra Maria, Luigi Colombo, Enrico Selva, L. Gastaldo, Linda Cavaletti, Flavia Marinelli, Ismaela Ciciliato
Publikováno v:
Biochemistry. 45:3692-3702
In the course of a microbial product screening aimed at the discovery of novel antibiotics acting on bacterial protein synthesis, a complex of three structurally related tetrapeptides, namely, GE81112 factors A, B, and B1, was isolated from a Strepto
Publikováno v:
European Journal of Biochemistry. 271:3146-3154
GE23077, a novel microbial metabolite recently isolated from Actinomadura sp. culture media, is a potent and selective inhibitor of bacterial RNA polymerase (RNAP). It inhibits Gram-positive (Bacillus subtilis) and Gram-negative (Escherichia coli) RN
Autor:
Emiliana Corti, Enrico Selva, Edoardo Sarubbi, L. Gastaldo, Flavia Marinelli, Michael Kurz, Nicoletta Montanini, Ismaela Ciciliato, Stefania Stefanelli, Daniele Losi
Publikováno v:
The Journal of Antibiotics. 57:210-217
GE 23077 factors A1, A2, B1 and B2 are novel antibiotics isolated from fermentation broths of an Actinomadura sp. strain. GE23077 antibiotics are cyclic peptides, which inhibit Escherichia coli RNA polymerase at nM concentrations. Both rifampicin-sen
Autor:
Enrico Selva
Publikováno v:
The Journal of antibiotics. 67(9)
Piero Sensi is probably known primarily for his role in the discovery of rifamycin and for developing it to be a drug of fundamental importance in the treatment of tuberculosis. He has also contributed to promote screening programs of microbial produ
Publikováno v:
The Journal of Antibiotics. 50:22-26
The development of a screen targeted to antibiotics which bind elongation factor Tu (EF-Tu) is described. The method was based on selection of antimicrobial activities which were antagonized by exogenous EF-Tu. Kirromycin, a known inhibitor of EF-Tu,
Autor:
Riccardo Bonfichi, Romeo Ciabatti, Paolo Tavecchia, Sergio Lociuro, Luigi Colombo, Michael Kurz, Ettore Marzorati, Enrico Selva
Publikováno v:
Tetrahedron. 52:8763-8774
Controlled acid hydrolysis of compound 2 resulted in the selective opening of the macrocycle while in basic condition a retro-aldol reaction occurred at the level of phenylserine thiazole. Compound 2 can be easily prepared from the natural antibiotic
Autor:
L. Colombo, D. Guglielmi, L. F. Zerilli, Sergio Stella, Enrico Selva, Cristina Sottani, R. Stradi
Publikováno v:
Rapid Communications in Mass Spectrometry. 10:409-412