Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Enrico Santinelli"'
Autor:
Michele Prisciandaro, Enrico Santinelli, Valeria Tomarchio, Maria Antonietta Tafuri, Cecilia Bonchi, Gloria Palazzo, Carolina Nobile, Alessandra Marinucci, Marcella Mele, Ombretta Annibali, Luigi Rigacci, Michele Vacca
Publikováno v:
Cells, Vol 13, Iss 7, p 586 (2024)
Achieving successful hematopoietic stem cell transplantation (HSCT) relies on two fundamental pillars: effective mobilization and efficient collection through apheresis to attain the optimal graft dose. These cornerstones pave the way for enhanced pa
Externí odkaz:
https://doaj.org/article/a4bc0d5179464148bc93899b82f704cc
Autor:
Jared A. Cohen, Francesca Maria Rossi, Antonella Zucchetto, Riccardo Bomben, Lodovico Terzi-di-Bergamo, Kari G. Rabe, Massimo Degan, Agostino Steffan, Jerry Polesel, Enrico Santinelli, Idanna Innocenti, Giovanna Cutrona, Giovanni D’Arena, Gabriele Pozzato, Francesco Zaja, Annalisa Chiarenza, Davide Rossi, Francesco Di Raimondo, Luca Laurenti, Massimo Gentile, Fortunato Morabito, Antonino Neri, Manlio Ferrarini, Christopher D. Fegan, Christopher J. Pepper, Giovanni Del Poeta, Sameer A. Parikh, Neil E. Kay, Valter Gattei
Publikováno v:
Haematologica, Vol 105, Iss 6 (2020)
We present a laboratory-based prognostic calculator (designated CRO score) to risk stratify treatment-free survival in early stage (Rai 0) chronic lymphocytic leukemia (CLL) developed using a training-validation model in a series of 1,879 cases from
Externí odkaz:
https://doaj.org/article/406de82bd1c54eb29a139ecbe8f5826e
Autor:
Valter Gattei, Giovanni Del Poeta, Francesco Di Raimondo, Francesco Zaja, Annalisa Chiarenza, Davide Rossi, Peter Hillmen, Anna Schuh, Anna Hockaday, Chris Pepper, Pietro Bulian, Jacopo Olivieri, Giovanni D'Arena, Gabriele Pozzato, Gilberto Fronza, Fortunato Morabito, Massimo Gentile, Annalisa Biagi, Enrico Santinelli, Jared A. Cohen, Jerry Polesel, Alessandra Braida, Michele Berton, Paola Nanni, Paola Varaschin, Ilaria Cattarossi, Eva Zaina, Massimo Degan, Elena Vendramini, Federico Pozzo, Erika Tissino, Antonella Zucchetto, Tiziana D'Agaro, Tamara Bittolo, Filippo Vit, Francesca Maria Rossi, Riccardo Bomben
Supplemental Material and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a4547e25c77872ace73d776ac6d523
https://doi.org/10.1158/1078-0432.22481244
https://doi.org/10.1158/1078-0432.22481244
Autor:
Valter Gattei, Giovanni Del Poeta, Francesco Di Raimondo, Francesco Zaja, Annalisa Chiarenza, Davide Rossi, Peter Hillmen, Anna Schuh, Anna Hockaday, Chris Pepper, Pietro Bulian, Jacopo Olivieri, Giovanni D'Arena, Gabriele Pozzato, Gilberto Fronza, Fortunato Morabito, Massimo Gentile, Annalisa Biagi, Enrico Santinelli, Jared A. Cohen, Jerry Polesel, Alessandra Braida, Michele Berton, Paola Nanni, Paola Varaschin, Ilaria Cattarossi, Eva Zaina, Massimo Degan, Elena Vendramini, Federico Pozzo, Erika Tissino, Antonella Zucchetto, Tiziana D'Agaro, Tamara Bittolo, Filippo Vit, Francesca Maria Rossi, Riccardo Bomben
Purpose:In chronic lymphocytic leukemia (CLL), TP53 mutations are associated with reduced survival and resistance to standard chemoimmunotherapy (CIT). Nevertheless, the clinical impact of subclonal TP53 mutations below 10% to 15% variant allele freq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b5399c0c7c142d422ba0c12bd19d37
https://doi.org/10.1158/1078-0432.c.6530643.v1
https://doi.org/10.1158/1078-0432.c.6530643.v1
Autor:
Peter Hillmen, Davide Rossi, Riccardo Bomben, Filippo Vit, Michele Berton, Gabriele Pozzato, Anna Hockaday, Giovanni D'Arena, Jared A. Cohen, Pietro Bulian, Ilaria Cattarossi, Fortunato Morabito, Massimo Degan, Jacopo Olivieri, Gilberto Fronza, Chris Pepper, Francesco Di Raimondo, Anna Schuh, Annalisa Biagi, Jerry Polesel, Antonella Zucchetto, Francesca Rossi, Erika Tissino, Massimo Gentile, Giovanni Del Poeta, Valter Gattei, Francesco Zaja, Paola Nanni, Elena Vendramini, Eva Zaina, Annalisa Chiarenza, Federico Pozzo, Tamara Bittolo, Enrico Santinelli, Tiziana D'Agaro, Paola Varaschin, Alessandra Braida
Publikováno v:
Clinical Cancer Research. 27:5566-5575
Purpose: In chronic lymphocytic leukemia (CLL), TP53 mutations are associated with reduced survival and resistance to standard chemoimmunotherapy (CIT). Nevertheless, the clinical impact of subclonal TP53 mutations below 10% to 15% variant allele fre
Autor:
Giovanni Del Poeta, Enrico Santinelli, Raffaele Dante Caposiena Caro, Luca Bianchi, Andrea Saggini, Augusto Orlandi
Publikováno v:
The American Journal of Dermatopathology. 41:940-944
B-cell chronic lymphocytic leukemia (CLL), a low-grade malignancy consisting of CD5(+), CD23(+), and CD43(+) small B lymphocytes, is the most frequent leukemia in the western world. Patients with CLL may exhibit skin changes characterized by histopat
Autor:
Annalisa Chiarenza, Valter Gattei, Agostino Steffan, Neil E. Kay, Giovanni D'Arena, Francesca Rossi, Christopher Fegan, Davide Rossi, Fortunato Morabito, Chris Pepper, Jerry Polesel, Massimo Degan, Kari G. Rabe, Riccardo Bomben, Manlio Ferrarini, Enrico Santinelli, Jared A. Cohen, Lodovico Terzi-di-Bergamo, Francesco Di Raimondo, Antonino Neri, Gabriele Pozzato, Luca Laurenti, Antonella Zucchetto, Massimo Gentile, Idanna Innocenti, Giovanna Cutrona, Sameer A. Parikh, Giovanni Del Poeta, Francesco Zaja
Publikováno v:
Haematologica
We present a laboratory-based prognostic calculator (designated CRO score) to risk stratify treatment-free survival in early stage (Rai 0) chronic lymphocytic leukemia developed using a training-validation model in a series of 1,879 cases from Italy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0bf164e9fb4f7c1af51f7f18befe908
http://sro.sussex.ac.uk/id/eprint/90077/1/Ah7g7W-haematol.2019.228171.full.pdf
http://sro.sussex.ac.uk/id/eprint/90077/1/Ah7g7W-haematol.2019.228171.full.pdf
Autor:
Tanja Nicole Hartmann, Ayed O. Ayed, Alexandre Chigaev, Valter Gattei, Gabriele Pozzato, Antonella Zucchetto, Enrico Santinelli, Jan A. Burger, Julia Christine Gutjahr, Massimiliano Postorino, Elisabeth Bayer, Erika Tissino, Riccardo Bomben, Giovanni Del Poeta, Michele Dal Bo, Adrian Wiestner, Elisa Ten Hacken, Dania Benedetti, Pietro Bulian, Inhye E. Ahn, Larry A. Sklar, Andrea Härzschel, Alessandra Ferrajoli, Francesca Rossi, Kari G. Chaffee, Annalisa Chiarenza, Francesco Zaja, Tait D. Shanafelt, Sarah E. M. Herman
Publikováno v:
The Journal of Experimental Medicine
Tissino et al. demonstrate that in chronic lymphocytic leukemia, the VLA-4 (CD49d/CD29) integrin remains activable by B cell receptor stimulation also upon in vitro and in vivo ibrutinib exposure. Clinically, ibrutinib-treated CD49d-positive CLL pati
Autor:
Annalisa Chiarenza, Pietro Bulian, Tanja Nicole Hartmann, Larry A. Sklar, Valter Gattei, Erika Tissino, Francesca Rossi, Antonella Nicolò, Hassan Jumaa, Alexandre Chigaev, Francesco Zaja, Riccardo Bomben, Gabriela Forestieri, Giovanni D'Arena, Moumita Datta, Giovanni Del Poeta, Tamara Bittolo, Antonella Zucchetto, Enrico Santinelli, Palash Chandra Maity, Gabriele Pozzato, Andrea Härzschel, Davide Rossi, Dania Benedetti, Francesco Di Raimondo
Publikováno v:
Blood. 134:849-849
Introduction. In chronic lymphocytic leukemia (CLL), CD49d, the alpha chain of the heterodimer CD49d/CD29 (VLA-4), is a strong negative prognosticator, and a key player of CLL microenvironmental interactions. The adhesive properties of VLA-4 can be r
Autor:
Antonella Zucchetto, Erika Tissino, Paola Nanni, Filippo Vit, Riccardo Bomben, Ilaria Cattarossi, Davide Rossi, Massimo Degan, Pietro Bulian, Giovanni D'Arena, Giovanni Del Poeta, Federico Pozzo, Tamara Bittolo, Eva Zaina, Annalisa Chiarenza, Francesca Rossi, Hillarj Chivilò, Enrico Santinelli, Tiziana D'Agaro, Valter Gattei, Mario Ballerini, Francesco Zaja, Gabriele Pozzato, Annalisa Biagi, Jerry Polesel, Francesco Di Raimondo
Publikováno v:
Blood. 134:480-480
Background. TP53 mutations (TP53mut) along with 17p13 deletion (del17p) are strong predictors of poor survival and refractoriness to chemo-immunotherapies (CIT) in chronic lymphocytic leukemia (CLL), and their analyses should be always performed befo