Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Enrico Massignani"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
RNA binding proteins (RBPs) bind RNAs through specific RNA-binding domains, generating multi-molecular complexes known as ribonucleoproteins (RNPs). Various post-translational modifications (PTMs) have been described to regulate RBP structure, subcel
Externí odkaz:
https://doaj.org/article/3255b4b505a94da3a097aa84a37e14d3
Autor:
Daniele Musiani, Roberto Giambruno, Enrico Massignani, Marica Rosaria Ippolito, Marianna Maniaci, Sriganesh Jammula, Daria Manganaro, Alessandro Cuomo, Luciano Nicosia, Diego Pasini, Tiziana Bonaldi
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1208-1222.e9 (2020)
Summary: Protein arginine methyltransferase 1 (PRMT1) is overexpressed in various human cancers and linked to poor response to chemotherapy. Various PRMT1 inhibitors are currently under development; yet, we do not fully understand the mechanisms unde
Externí odkaz:
https://doaj.org/article/3943a66ffcdc4ffcb5e31b0f7d05112c
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628621
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c56575c5c07e30018f4d6e2ac1eea05
https://doi.org/10.1007/978-1-0716-2863-8_14
https://doi.org/10.1007/978-1-0716-2863-8_14
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2603
Protein methylation is a widespread post-translational modification (PTM) involved in several important biological processes including, but not limited to, RNA splicing, signal transduction, translation, and DNA repair. Liquid chromatography-tandem m
Publikováno v:
Journal of visualized experiments : JoVE. (182)
Protein Arginine (R)-methylation is a widespread protein post-translational modification (PTM) involved in the regulation of several cellular pathways, including RNA processing, signal transduction, DNA damage response, miRNA biogenesis, and translat
Autor:
Enrico Massignani, Roberto Giambruno, Marianna Maniaci, Luciano Nicosia, Avinash Yadav, Alessandro Cuomo, Francesco Raimondi, Tiziana Bonaldi
Protein arginine (R) methylation is a post-translational modification involved in various biological processes, such as RNA splicing, DNA repair, immune response, signal transduction, and tumor development. Although several advancements were made in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f158d0dbcece490e6fc8cea652556ed
https://hdl.handle.net/11384/129363
https://hdl.handle.net/11384/129363
Autor:
Francesco Nicassio, Francesca Patuzzo, Valeria Spadotto, Marianna Maniaci, Marija Mihailovich, Roberto Giambruno, Tiziana Bonaldi, Enrico Massignani, Francesco Ghini
Publikováno v:
Nucleic Acids Research
MicroRNA (miRNA) biogenesis is a tightly controlled multi-step process operated in the nucleus by the activity of the Microprocessor and its associated proteins. Through high resolution mass spectrometry (MS)- proteomics we discovered that this compl
Autor:
Tiziana Bonaldi, Roberto Giambruno, Enrico Massignani, Luciano Nicosia, Avinash Yadav, Francesco Raimondi, Alessandro Cuomo, Marianna Maniaci
Protein Arginine (R) methylation is a post-translational modification involved in various biological processes, such as RNA splicing, DNA repair, immune response, signal transduction, and tumour development. Although several advancements were made in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90de2d3e0d23b255d43fa3be54a3817a
https://doi.org/10.1101/2021.09.20.461082
https://doi.org/10.1101/2021.09.20.461082
Autor:
Fabio Bedin, Tiziana Bonaldi, Roberto Ravasio, Elena Ceccacci, Isabella Pallavicini, Saverio Minucci, Luciano Nicosia, Enrico Massignani, Francesca Ludovica Boffo
The histone de-methylase LSD1 is over-expressed in haematological tumours and has emerged as a promising target for anti-cancer treatment, so that several LSD1 inhibitors are under development and testing, in pre-clinical and clinical settings. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b36fed5622d5260a8e797de2ce830a5
https://doi.org/10.1101/2021.02.16.431315
https://doi.org/10.1101/2021.02.16.431315
Autor:
Tim C. P. Somervaille, Roberto Ravasio, Luciano Nicosia, Tiziana Bonaldi, Isabella Pallavicini, Enrico Massignani, Fabio Bedin, Saverio Minucci, Elena Ceccacci, Francesca Ludovica Boffo, Fabio Conforti
Publikováno v:
Oncogene
The histone demethylase LSD1 is over-expressed in hematological tumors and has emerged as a promising target for anticancer treatment, so that several LSD1 inhibitors are under development and testing, in preclinical and clinical settings. However, t