Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Enrico Malito"'
Autor:
Wayne D. Harshbarger, Genevieve Holzapfel, Nishat Seraj, Sai Tian, Chelsy Chesterman, Zongming Fu, Yan Pan, Claire Harelson, Dongjun Peng, Ying Huang, Sumana Chandramouli, Enrico Malito, Matthew James Bottomley, James Williams
Publikováno v:
Vaccines, Vol 12, Iss 10, p 1111 (2024)
Background: Varicella zoster virus (VZV) is the causative agent for chickenpox and herpes zoster (HZ, shingles). HZ is a debilitating disease affecting elderly and immunocompromised populations. Glycoprotein E (gE) is indispensable for viral replicat
Externí odkaz:
https://doaj.org/article/ffca2f09de724859bed86bdff3c33400
Autor:
Daniele Veggi, Enrico Malito, Paola Lo Surdo, Werner Pansegrau, Valentina Rippa, Newton Wahome, Silvana Savino, Vega Masignani, Mariagrazia Pizza, Matthew J. Bottomley
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2070-2081 (2022)
Invasive meningococcal disease can cause fatal sepsis and meningitis and is a global health threat. Factor H binding protein (fHbp) is a protective antigen included in the two currently available vaccines against serogroup B meningococcus (MenB). FHb
Externí odkaz:
https://doaj.org/article/d7cd09e242a249cfa9f272717e3367cb
Autor:
Sophie McKenna, Enrico Malito, Sarah L. Rouse, Francesca Abate, Giuliano Bensi, Emiliano Chiarot, Francesca Micoli, Francesca Mancini, Danilo Gomes Moriel, Guido Grandi, Danuta Mossakowska, Max Pearson, Yingqi Xu, James Pease, Shiranee Sriskandan, Immaculada Margarit, Matthew J. Bottomley, Stephen Matthews
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 650-660 (2020)
Over 18 million disease cases and half a million deaths worldwide are estimated to be caused annually by Group A Streptococcus. A vaccine to prevent GAS disease is urgently needed. SpyCEP (Streptococcus pyogenes Cell-Envelope Proteinase) is a surface
Externí odkaz:
https://doaj.org/article/b595bca1fd7a42ec867d442b4d2f3cb2
Autor:
Wayne Harshbarger, Priyanka D. Abeyrathne, Sai Tian, Ying Huang, Sumana Chandramouli, Matthew James Bottomley, Enrico Malito
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory tract infections resulting in medical intervention and hospitalizations during infancy and early childhood, and vaccination against RSV remains a public health prio
Externí odkaz:
https://doaj.org/article/ae7c2f6a21af45829645ba478d1f0316
Autor:
Wayne Harshbarger, Sai Tian, Newton Wahome, Ankita Balsaraf, Deep Bhattacharya, Desheng Jiang, Ratnesh Pandey, Kunal Tungare, Kristian Friedrich, Nurjahan Mehzabeen, Marco Biancucci, Diana Chinchilla-Olszar, Corey P Mallett, Ying Huang, Zihao Wang, Matthew James Bottomley, Enrico Malito, Sumana Chandramouli
Publikováno v:
PLoS Pathogens, Vol 16, Iss 11, p e1008943 (2020)
Respiratory syncytial virus (RSV) is a global public health burden for which no licensed vaccine exists. To aid vaccine development via increased understanding of the protective antibody response to RSV prefusion glycoprotein F (PreF), we performed s
Externí odkaz:
https://doaj.org/article/98f5af6f2dbe4087aa5a737f65ccd637
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 58-68 (2016)
For over 100 years, vaccines have been one of the most effective medical interventions for reducing infectious disease, and are estimated to save millions of lives globally each year. Nevertheless, many diseases are not yet preventable by vaccination
Externí odkaz:
https://doaj.org/article/7b64fc476dcc42f09fa45c6294126ff2
Autor:
Alessia Liguori, Lucia Dello Iacono, Giulietta Maruggi, Barbara Benucci, Marcello Merola, Paola Lo Surdo, Jacinto López-Sagaseta, Mariagrazia Pizza, Enrico Malito, Matthew J. Bottomley
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Neisseria meningitidis serogroup B (MenB) is a major cause of sepsis and invasive meningococcal disease. A multicomponent vaccine, 4CMenB, is approved for protection against MenB. Neisserial adhesin A (NadA) is one of the main vaccine antige
Externí odkaz:
https://doaj.org/article/27786e9b8cd34730b7b46d70ceb020ba
Autor:
Martina Maritan, Daniele Veggi, Roberta Cozzi, Lucia Dello Iacono, Erika Bartolini, Paola Lo Surdo, Giulietta Maruggi, Glen Spraggon, Matthew J Bottomley, Enrico Malito
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201922 (2018)
Neisserial heparin binding antigen (NHBA) is one of three main recombinant protein antigens in 4CMenB, a vaccine for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B. NHBA is a surface-exposed lipoprotein
Externí odkaz:
https://doaj.org/article/cee79a5c92024499b9bc57caebc05e1d
Autor:
Alessia Liguori, Enrico Malito, Paola Lo Surdo, Luca Fagnocchi, Francesca Cantini, Andreas F Haag, Sébastien Brier, Mariagrazia Pizza, Isabel Delany, Matthew J Bottomley
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005557 (2016)
Neisseria adhesin A (NadA) is present on the meningococcal surface and contributes to adhesion to and invasion of human cells. NadA is also one of three recombinant antigens in the recently-approved Bexsero vaccine, which protects against serogroup B
Externí odkaz:
https://doaj.org/article/fe26d987d2f647f6a06de8fb4b7f80d5
Autor:
Roberta Cozzi, Enrico Malito, Maddalena Lazzarin, Annalisa Nuccitelli, Andrea Castagnetti, Matthew J Bottomley, Immaculada Margarit, Domenico Maione, C Daniela Rinaudo
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125875 (2015)
Group B Streptococcus (GBS) is a major cause of invasive disease in infants. Like other Gram-positive bacteria, GBS uses a sortase C-catalyzed transpeptidation mechanism to generate cell surface pili from backbone and ancillary pilin precursor substr
Externí odkaz:
https://doaj.org/article/d63fff1033f4475e9a94fdcb7d942118