Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Enrico M.A. Fassi"'
Autor:
Enrico M.A. Fassi, Jacopo Sgrignani, Gianluca D'Agostino, Valentina Cecchinato, Maura Garofalo, Giovanni Grazioso, Mariagrazia Uguccioni, Andrea Cavalli
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 17, Iss , Pp 886-894 (2019)
High-mobility Group Box 1 (HMGB1) is an abundant protein present in all mammalian cells and involved in several processes. During inflammation or tissue damage, HMGB1 is released in the extracellular space and, depending on its redox state, can form
Externí odkaz:
https://doaj.org/article/b1fea047a25c459291dd726dab1ead9a
Autor:
Maura Garofalo, Mattia Pedotti, Enrico M.A. Fassi, Andrea Cavalli, Mariagrazia Uguccioni, Valentina Cecchinato, Luca Varani, Jacopo Sgrignani, Luca Simonelli, Gabriela Danelon, Gianluca D'Agostino, Giovanni Grazioso
Publikováno v:
Journal of Medicinal Chemistry. 64:13439-13450
During inflammatory reactions, the production and release of chemotactic factors guide the recruitment of selective leukocyte subpopulations. The alarmin HMGB1 and the chemokine CXCL12, both released in the microenvironment, can form a heterocomplex,
Autor:
Giovanna Boschin, Anna Arnoldi, Gabriella Roda, Gilda Aiello, Martina Bartolomei, Giovanni Grazioso, Yuchen Li, Enrico M.A. Fassi, Carmen Lammi, Carlotta Bollati
Publikováno v:
Nutrients; Volume 13; Issue 5; Pages: 1624
Nutrients
Nutrients, Vol 13, Iss 1624, p 1624 (2021)
Nutrients
Nutrients, Vol 13, Iss 1624, p 1624 (2021)
Chlorella pyrenoidosa (C. pyrenoidosa) is a microalgae species with a remarkably high protein content that may potentially become a source of hypotensive and hypoglycemic peptides. In this study, C. pyrenoidosa proteins were extracted and hydrolyzed
Publikováno v:
ChemMedChem. 15(16)
Proprotein convertase subtilisin/kexin 9 (PCSK9) is a notable target for the treatment of hypercholesterolemia because it regulates the population of the low-density lipoprotein receptor (LDLR) on liver cells. The PCSK9 zymogen is a serine protease t
Autor:
Maura Garofalo, Mariagrazia Uguccioni, Jacopo Sgrignani, Valentina Cecchinato, Andrea Cavalli, Enrico M.A. Fassi, Gianluca D'Agostino, Gabriela Danelon, Giovanni Grazioso
During inflammatory reactions, the production and release of chemotactic factors guide the recruitment of selective leukocyte subpopulations. HMGB1 and the chemokine CXCL12, both released in the microenvironment, form a heterocomplex, which exclusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3725ac8bd05361f8aa1b5e58c6f9b7e9
https://doi.org/10.1101/2019.12.18.878504
https://doi.org/10.1101/2019.12.18.878504
Autor:
Agostino Casapullo, Enrico M.A. Fassi, Sara Sattin, Elva Morretta, Giorgio Colombo, Matteo Costantini, Chiara Cassiano
Publikováno v:
Bioorganic Chemistry. 115:105258
Hsp90 (i.e., Heat shock protein 90) is a well-established therapeutic target for several diseases, ranging from misfolding-related disfunctions to cancer. In this framework, we have developed in recent years a family of benzofuran compounds that act
Autor:
Giulia Ranaldi, Enrico M.A. Fassi, Gilda Aiello, Simonetta Ferruzza, Giovanni Grazioso, Carlotta Bollati, Yula Sambuy, Jianqiang Li, Carmen Lammi, Anna Arnoldi, Martina Bartolomei
Publikováno v:
Nutrients
Nutrients, Vol 13, Iss 863, p 863 (2021)
Nutrients; Volume 13; Issue 3; Pages: 863
Nutrients, Vol 13, Iss 863, p 863 (2021)
Nutrients; Volume 13; Issue 3; Pages: 863
P5 (LILPKHSDAD) is a hypocholesterolemic peptide from lupin protein with a multi-target activity, since it inhibits both 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCoAR) and proprotein convertase subtilisin/kexin type-9 (PCSK9). This work sh
Autor:
Marcella Chiari, Maria Teresa Odinolfi, Marina Cretich, Ilda D'Annessa, Alessandro Romanato, Dario Brambilla, Giorgio Colombo, Greta Bergamaschi, Alessandro Gori, Enrico M.A. Fassi, Francesco Damin
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 8
International journal of molecular sciences
20 (2019). doi:10.3390/ijms20081921
info:cnr-pdr/source/autori:Bergamaschi G.; Fassi E.M.A.; Romanato A.; D'Annessa I.; Odinolfi M.T.; Brambilla D.; Damin F.; Chiari M.; Gori A.; Colombo G.; Cretich M./titolo:Computational analysis of dengue virus envelope protein (E) reveals an epitope with flavivirus immunodiagnostic potential in peptide microarrays/doi:10.3390%2Fijms20081921/rivista:International journal of molecular sciences (Print)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:20
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1921 (2019)
Volume 20
Issue 8
International journal of molecular sciences
20 (2019). doi:10.3390/ijms20081921
info:cnr-pdr/source/autori:Bergamaschi G.; Fassi E.M.A.; Romanato A.; D'Annessa I.; Odinolfi M.T.; Brambilla D.; Damin F.; Chiari M.; Gori A.; Colombo G.; Cretich M./titolo:Computational analysis of dengue virus envelope protein (E) reveals an epitope with flavivirus immunodiagnostic potential in peptide microarrays/doi:10.3390%2Fijms20081921/rivista:International journal of molecular sciences (Print)/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:20
International Journal of Molecular Sciences, Vol 20, Iss 8, p 1921 (2019)
The mosquito-borne viral disease caused by the Dengue virus is an expanding global threat. Diagnosis in low-resource-settings and epidemiological surveillance urgently requires new immunoprobes for serological tests. Structure-based epitope predictio