Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Enrico M, Novelli"'
Autor:
Philip Sasi, Abel Makubi, Raphael Z. Sangeda, Mariam Y. Ngaeje, Bruno P. Mmbando, Joseph Soka, Caterina Rosano, Alex S. Magesa, Sharon E. Cox, Julie Makani, Enrico M. Novelli
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-8 (2024)
Abstract Background Sickle cell anemia (SCA) prevalence remains high in sub-Saharan Africa. Long-term treatment with hydroxyurea (HU) increases survival, however, poor adherence to treatment could limit effectiveness. Whilst HU treatment adherence is
Externí odkaz:
https://doaj.org/article/6b1748037b71473fb053885fc70ad934
Autor:
Andrew W. Swartz, Enrico M. Novelli
Publikováno v:
Clinical Case Reports, Vol 12, Iss 2, Pp n/a-n/a (2024)
Key Clinical Message Warm Autoimmune Hemolytic Anemia (WAHA) is the most common form of autoimmune hemolysis and there is a growing body of evidence of an association between SARS‐CoV‐2 infection, WAHA and a hyperinflammatory state, including hem
Externí odkaz:
https://doaj.org/article/103a2c6fa978426a836a4818db2e0be8
Autor:
Qin Zhu, Clayton E. Barnes, Philip Z. Mannes, Joseph D. Latoche, Kathryn E. Day, Jessie R. Nedrow, Enrico M. Novelli, Carolyn J. Anderson, Sina Tavakoli
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Background The lack of noninvasive methods for assessment of dysregulated inflammation as a major driver of fibrosis (i.e., inflammation-fibrosis axis) has been a major challenge to precision management of fibrotic lung diseases. Here, we de
Externí odkaz:
https://doaj.org/article/dc0119190bb043868f78ad11e5290278
Autor:
Tomasz W. Kaminski, Omika Katoch, Ziming Li, Corrine B. Hanway, Rikesh K. Dubey, Adekunle Alagbe, Tomasz Brzoska, Hong Zhang, Prithu Sundd, Gregory J. Kato, Enrico M. Novelli, Tirthadipa Pradhan-Sundd
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Sickle cell disease (SCD) is a monogenic disorder that affects 100,000 African-Americans and millions of people worldwide. Intra-erythrocytic polymerization of sickle hemoglobin (HbS) promotes erythrocyte sickling, impaired rheology, ischemia and hem
Externí odkaz:
https://doaj.org/article/5d47f36e3bc94fdd9f804d4cfcf354eb
Autor:
Matthew Gorgone, Enrico M. Novelli, Simmi Patel, Phillip E. Lamberty, Laura M. De Castro, Mark T. Gladwin, Stephanie I. Maximous
Publikováno v:
Respiratory Medicine Case Reports, Vol 39, Iss , Pp 101724- (2022)
Patients with sickle cell disease can develop acute chest syndrome and are at high risk of developing pulmonary thrombosis. We report a case of a young woman with sickle cell disease who was hospitalized for vaso-occlusive crisis and subsequently dev
Externí odkaz:
https://doaj.org/article/c7d1c112b00b4f03b3ef7bd758fa53ba
Autor:
Rimi Hazra, Holland Hubert, Lynda Little-Ihrig, Samit Ghosh, Solomon Ofori-Acquah, Xiaoming Hu, Enrico M Novelli
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 692 (2023)
Occlusion of cerebral blood vessels causes acute cerebral hypoxia—an important trigger of ischemic white matter injury and stroke in sickle cell disease (SCD). While chronic hypoxia triggers compensatory neuroprotection via insulin-like growth fact
Externí odkaz:
https://doaj.org/article/ecc40c6704b24073a57dc132f79ffa4c
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2679-2687 (2019)
Abstract: Sickle cell disease (SCD) is an inherited hemoglobinopathy caused by a single point mutation in the β-globin gene. As a consequence, deoxygenated hemoglobin polymerizes triggering red blood cell sickling and hemolysis, vaso-occlusion, and
Externí odkaz:
https://doaj.org/article/cf5b8625799a4c7191c4fd39d8fb6a7e
Autor:
Tales Santini, Minseok Koo, Nadim Farhat, Vinicius P. Campos, Salem Alkhateeb, Marcelo A.C. Vieira, Meryl A. Butters, Caterina Rosano, Howard J. Aizenstein, Joseph Mettenburg, Enrico M. Novelli, Tamer S. Ibrahim
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102655- (2021)
Sickle cell disease (SCD) is an inherited hemoglobinopathy that causes organ dysfunction, including cerebral vasculopathy and neurological complications. Hippocampal segmentation with newer and advanced 7 Tesla (7T) MRI protocols has revealed atrophy
Externí odkaz:
https://doaj.org/article/6c9500dd1a404c179fed11a8cdb3e218
Autor:
Rahul, Chaudhary, Michael, Bashline, Enrico M, Novelli, Kevin P, Bliden, Udaya S, Tantry, Oladipupo, Olafiranye, Aref, Rahman, Paul A, Gurbel, John J, Pacella
Publikováno v:
International Journal of Cardiology. 369:1-4
Among patients who present with acute myocardial infarction (MI), 2-6% are found to have non-obstructive coronary arteries (NOCA). Patients with MINOCA are more commonly women and present at a younger age (51-59 years). The influence of sex on advers
Autor:
Stevan P, Tofovic, Victor P, Bilan, Olga, Rafikova, Frank, Schneider, Enrico M, Novelli, Edwin K, Jackson
Publikováno v:
PRILOZI. 43:5-20
Vascular and lung injury are well established complications associated with hemolytic disorders, and hemolysis associated pulmonary hypertension (PH) has emerged as the most serious complication of sickle cell disease. The causal relationship between