Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Enrico Lucarelli"'
Autor:
Thomas Chow, William Humble, Enrico Lucarelli, Carmine Onofrillo, Peter F. Choong, Claudia Di Bella, Serena Duchi
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110251- (2024)
Summary: Osteosarcoma is a highly aggressive primary bone tumor that has seen little improvement in survival rates in the past three decades. Preclinical studies are conducted on a small pool of commercial cell lines which may not fully reflect the g
Externí odkaz:
https://doaj.org/article/43ddd9fb653b43e7a293ade9a7e87f9d
Autor:
Ania Naila Guerrieri, Chiara Bellotti, Marianna Penzo, Marta Columbaro, Micaela Pannella, Alessandro De Vita, Marco Gambarotti, Laura Mercatali, Roberta Laranga, Barbara Dozza, Silvia Vanni, Serena Corsini, Tommaso Frisoni, Giacomo Miserocchi, Toni Ibrahim, Enrico Lucarelli
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Myxofibrosarcoma is a rare malignant soft tissue sarcoma characterised by multiple local recurrence and can become of higher grade with each recurrence. Consequently, myxofibrosarcoma represents a burden for patients, a challenge
Externí odkaz:
https://doaj.org/article/ea0f824c2407483d92495879733be726
Autor:
Stephanie E. Doyle, Micaela Pannella, Carmine Onofrillo, Chiara Bellotti, Claudia Di Bella, Cathal D. O’Connell, Elena Pirogova, Enrico Lucarelli, Serena Duchi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Tissue-engineered implants for bone regeneration require consideration regarding their mineralization and vascularization capacity. Different geometries, such as biomimetic designs and lattices, can influence the mechanical properties and the vascula
Externí odkaz:
https://doaj.org/article/9e4a89dc9e4a4dad9a4cbc78c36c58ee
Autor:
Veronica Giusti, Giacomo Miserocchi, Giulia Sbanchi, Micaela Pannella, Claudia Maria Hattinger, Marilena Cesari, Leonardo Fantoni, Ania Naila Guerrieri, Chiara Bellotti, Alessandro De Vita, Chiara Spadazzi, Davide Maria Donati, Monica Torsello, Enrico Lucarelli, Toni Ibrahim, Laura Mercatali
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1921 (2024)
Musculoskeletal sarcomas pose major challenges to researchers and clinicians due to their rarity and heterogeneity. Xenografting human cells or tumor fragments in rodents is a mainstay for the generation of cancer models and for the preclinical trial
Externí odkaz:
https://doaj.org/article/b62b69d1957b47d4ae7db370d746fddf
Autor:
Laura Mercatali, Silvia Vanni, Giacomo Miserocchi, Chiara Liverani, Chiara Spadazzi, Claudia Cocchi, Chiara Calabrese, Lorena Gurrieri, Valentina Fausti, Nada Riva, Damiano Genovese, Enrico Lucarelli, Maria Letizia Focarete, Toni Ibrahim, Luana Calabrò, Alessandro De Vita
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
In the field of nanomedicine a multitude of nanovectors have been developed for cancer application. In this regard, a less exploited target is represented by connective tissue. Sarcoma lesions encompass a wide range of rare entities of mesenchymal or
Externí odkaz:
https://doaj.org/article/f885ba5b521043b3ab3517835c5c98b4
Autor:
Silvia Vanni, Alessandro De Vita, Lorena Gurrieri, Valentina Fausti, Giacomo Miserocchi, Chiara Spadazzi, Chiara Liverani, Claudia Cocchi, Chiara Calabrese, Alberto Bongiovanni, Nada Riva, Laura Mercatali, Federica Pieri, Roberto Casadei, Enrico Lucarelli, Toni Ibrahim
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Myxofibrosarcoma (MFS) is a common entity of adult soft tissue sarcomas (STS) characterized by a predilection of the extremities and a high local recurrence rate. Originally classified as a myxoid variant of malignant fibrous histiocytoma, this muscu
Externí odkaz:
https://doaj.org/article/4aa06f9cbc64417c87a8626b0e56f7e8
Autor:
Stefania Lenna, Chiara Bellotti, Serena Duchi, Elisa Martella, Marta Columbaro, Barbara Dozza, Marco Ballestri, Andrea Guerrini, Giovanna Sotgiu, Tommaso Frisoni, Luca Cevolani, Greta Varchi, Mauro Ferrari, Davide Maria Donati, Enrico Lucarelli
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Abstract Background Osteosarcoma (OS) is an aggressive malignant neoplasm that still suffers from poor prognosis in the case of distal metastases or occurrence of multi-drug resistance. It is therefore crucial to find novel therapeutic options able t
Externí odkaz:
https://doaj.org/article/52e13201ade24a7c9c0de9d76601314c
Autor:
Elisa Martella, Barbara Dozza, Claudia Ferroni, Clement Osuru Obeyok, Andrea Guerrini, Daniele Tedesco, Ilse Manet, Giovanna Sotgiu, Marta Columbaro, Marco Ballestri, Lucia Martini, Milena Fini, Enrico Lucarelli, Greta Varchi, Serena Duchi
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 677 (2022)
Osteosarcoma treatment is moving towards more effective combination therapies. Nevertheless, these approaches present distinctive challenges that can complicate the clinical translation, such as increased toxicity and multi-drug resistance. Drug co-e
Externí odkaz:
https://doaj.org/article/f4c39e9be1c4426181aaa10503731be9
Autor:
Ania Naila Guerrieri, Monica Montesi, Simone Sprio, Roberta Laranga, Laura Mercatali, Anna Tampieri, Davide Maria Donati, Enrico Lucarelli
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Bone is the third most frequent site of metastasis, with a particular incidence in breast and prostate cancer patients. For example, almost 70% of breast cancer patients develop several bone metastases in the late stage of the disease. Bone metastase
Externí odkaz:
https://doaj.org/article/74d30c221fe949278ffbd4e76d3c1559
Autor:
Ilaria De Santis, Luca Lorenzini, Marzia Moretti, Elisa Martella, Enrico Lucarelli, Laura Calzà, Alessandro Bevilacqua
Publikováno v:
Sensors, Vol 21, Iss 19, p 6385 (2021)
Cellular and subcellular spatial colocalization of structures and molecules in biological specimens is an important indicator of their co-compartmentalization and interaction. Presently, colocalization in biomedical images is addressed with visual in
Externí odkaz:
https://doaj.org/article/d37eb69d39c14e7cbbb86aaa62400450