Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Enrico, Ragni"'
Autor:
Enrico Ragni, Paola De Luca, Simona Landoni, Federico Valli, Leonardo Mortati, Silvia Palombella, Giuseppe Talò, Matteo Moretti, Laura de Girolamo
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 442-457 (2024)
Introduction: Extracellular vesicles from mesenchymal stromal cells (MSC-EVs) are potent stimulators of naïve cartilage and their injection is studied in clinical trials for cartilage lesions, since often cartilage repaired with conventional approac
Externí odkaz:
https://doaj.org/article/0b036a6a8fde4602aa7c67f0accd68f7
Autor:
Enrico Ragni, Simona Piccolo, Michela Taiana, Caterina Visconte, Giulio Grieco, Laura de Girolamo
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 1, Pp 842-855 (2024)
Due to the scientific success of in vitro and in vivo model studies, the interest in using mesenchymal stromal cells (MSCs) for the treatment of orthopaedic conditions is growing. In the context of osteoarthritis (OA), MSCs, and, in particular, those
Externí odkaz:
https://doaj.org/article/6c32099befed49b080f9e7ba0a16219d
Autor:
Alessandra Colombini, Gianluca Doro, Enrico Ragni, Luca Forte, Laura de Girolamo, Fabio Zerbinati
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Knee osteoarthritis (OA) is a progressive and degenerative condition. Several pharmacological and non-pharmacological treatments are able to improve the OA symptoms and the structural characteristics of the affected joints. Among
Externí odkaz:
https://doaj.org/article/bb3a823d3fec471fb879c3a88145c9a3
Autor:
Enrico Ragni, Simona Piccolo, Paola De Luca, Michela Taiana, Giulio Grieco, Laura de Girolamo
Publikováno v:
Cells, Vol 13, Iss 2, p 167 (2024)
Among the available therapeutics for the conservative treatment of osteoarthritis (OA), mesenchymal stromal cells (MSCs)-based products appear to be the most promising. Alongside minimally manipulated cell-based orthobiologics, where MSCs are the eng
Externí odkaz:
https://doaj.org/article/d8f20a3371c44f9d936bf1b054fb6738
Autor:
Alessandra Colombini, Francesca Libonati, Silvia Lopa, Enrico Ragni, Paola De Luca, Luigi Zagra, Federico Sinigaglia, Matteo Moretti, Laura de Girolamo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The purpose of the present study is to predict by bioinformatics the activity of the extracellular vesicle (EV)-embedded micro RNA (miRNAs) secreted by cartilage cells (CCs), adipose tissue-derived- (ASCs), and bone marrow-derived stem cells (BMSCs)
Externí odkaz:
https://doaj.org/article/0edafc9b952e440ba4348cdbd7456fec
Autor:
Enrico Ragni, Andrea Papait, Carlotta Perucca Orfei, Antonietta Rosa Silini, Alessandra Colombini, Marco Viganò, Francesca Libonati, Ornella Parolini, Laura deGirolamo
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 7, Pp 1044-1062 (2021)
Abstract Human amniotic membrane‐derived mesenchymal stromal cells (hAMSCs) are easily obtained in large quantities and free from ethical concerns. Promising therapeutic results for both hAMSCs and their secreted factors (secretome) were described
Externí odkaz:
https://doaj.org/article/14c321ff07604eaea4507b2fc0468005
Autor:
Andrea Papait, Enrico Ragni, Anna Cargnoni, Elsa Vertua, Pietro Romele, Alice Masserdotti, Carlotta Perucca Orfei, Patrizia Bonassi Signoroni, Marta Magatti, Antonietta R. Silini, Laura De Girolamo, Ornella Parolini
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties demonstrated in vitro and in vivo in various diseases in which the dysregulated immune system plays a major role. The immunomodulatory and pro-regenerative effects of
Externí odkaz:
https://doaj.org/article/b714ab05226d408683be886113525d4d
Autor:
Chiara Giannasi, Stefania Niada, Cinzia Magagnotti, Enrico Ragni, Annapaola Andolfo, Anna Teresa Brini
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background In the last years, several clinical trials have proved the safety and efficacy of adipose-derived stem/stromal cells (ASC) in contrasting osteoarthritis (OA). Since ASC act mainly through paracrine mechanisms, their secretome (con
Externí odkaz:
https://doaj.org/article/eda8f13c124a4a99ae0b78bf23b432a1
Autor:
Enrico Ragni, Carlotta Perucca Orfei, Paola De Luca, Carlotta Mondadori, Marco Viganò, Alessandra Colombini, Laura de Girolamo
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-19 (2020)
Abstract Background Mesenchymal stromal cell (MSC)-enriched products showed positive clinical outcomes in regenerative medicine, where tissue restoration and inflammation control are needed. GMP-expanded MSCs displayed an even higher potential due to
Externí odkaz:
https://doaj.org/article/65882c7b49054d5484e583d869afe1da
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/fb5f6b16e7fa45fd956d66e26553315a