Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Enrico, De Smaele"'
Autor:
Rosa Molfetta, Mario Lecce, Nadia D. Milito, Erisa Putro, Giuseppe Pietropaolo, Caterina Marangio, Gianluca Scarno, Marta Moretti, Enrico De Smaele, Tiziana Santini, Giovanni Bernardini, Giuseppe Sciumè, Angela Santoni, Rossella Paolini
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-13 (2023)
Abstract Mast cells (MCs) are multifaceted innate immune cells often present in the tumor microenvironment (TME). Several recent findings support their contribution to the transition from chronic inflammation to cancer. However, MC-derived mediators
Externí odkaz:
https://doaj.org/article/2ea10411882447939b7d4f8be5646876
Autor:
Andrea Arena, Maria Anele Romeo, Agnese Po, Rossella Benedetti, Maria Saveria Gilardini Montani, Roberta Gonnella, Roberta Santarelli, Aurelia Gaeta, Enrico De Smaele, Mara Cirone
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Post-transplant lymphoproliferative disorders (PTLD) are a group of heterogeneous diseases originating in conditions of immune deficiency, whose main driver is considered to be Epstein-Barr virus (EBV). Here, we explored the role of IRE1alph
Externí odkaz:
https://doaj.org/article/fa4b80a8095b4249ad84724846ecdcf6
Autor:
Roberto Bei, Monica Benvenuto, Chiara Focaccetti, Sara Fazi, Marta Moretti, Daniela Nardozi, Valentina Angiolini, Sara Ciuffa, Loredana Cifaldi, Raffaele Carrano, Camilla Palumbo, Martino Tony Miele, Riccardo Bei, Giovanni Barillari, Vittorio Manzari, Enrico De Smaele, Andrea Modesti, Laura Masuelli
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Malignant mesothelioma (MM) is a rare orphan aggressive neoplasia with low survival rates. Among the other signaling pathways, ErbB receptors and Hh signaling are deregulated in MM. Thus, molecules involved in these signaling pathways could
Externí odkaz:
https://doaj.org/article/1e16b0cd67584040a68ba77a8a61a781
Autor:
Luana Abballe, Vincenzo Alfano, Celeste Antonacci, Maria Giuseppina Cefalo, Antonella Cacchione, Giada Del Baldo, Marco Pezzullo, Agnese Po, Marta Moretti, Angela Mastronuzzi, Enrico De Smaele, Elisabetta Ferretti, Franco Locatelli, Evelina Miele
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Development of the cerebellum is characterized by rapid proliferation of cerebellar granule cell precursors (GCPs) induced by paracrine stimulation of Sonic hedgehog (Shh) signaling from Purkinje cells, in the external granular layer (EGL). Then, gra
Externí odkaz:
https://doaj.org/article/f757549346b04ac7b13acf5e6cf7ad88
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract The human family of Potassium (K+) Channel Tetramerization Domain (KCTD) proteins counts 25 members, and a significant number of them are still only partially characterized. While some of the KCTDs have been linked to neurological disorders
Externí odkaz:
https://doaj.org/article/f94336ba182843288a4bf7c42f536954
Autor:
Carlo De Blasio, Nagendra Verma, Marta Moretti, Samantha Cialfi, Azzurra Zonfrilli, Matteo Franchitto, Federica Truglio, Enrico De Smaele, Hidenori Ichijo, Isao Naguro, Isabella Screpanti, Claudio Talora
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Both CDKN1A (p21 Waf1/Cip1) and Apoptosis signal-regulating kinase 1 (ASK1) play important roles in tumorigenesis. The role of p21 Waf1/Cip1 in attenuating ASK1-induced apoptosis by various stress conditions is well established. However, how
Externí odkaz:
https://doaj.org/article/cd3c8cd4d2384a64b4db6cc4a373c486
Autor:
Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti
Publikováno v:
Molecular Oncology, Vol 15, Iss 2, Pp 523-542 (2021)
Persistent mortality rates of medulloblastoma (MB) and severe side effects of the current therapies require the definition of the molecular mechanisms that contribute to tumor progression. Using cultured MB cancer stem cells and xenograft tumors gene
Externí odkaz:
https://doaj.org/article/3ec33b21a6324dbd9f6e0a27e592e22c
Autor:
Muhlis Akman, Dimas Carolina Belisario, Iris Chiara Salaroglio, Joanna Kopecka, Massimo Donadelli, Enrico De Smaele, Chiara Riganti
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Solid tumors often grow in a micro-environment characterized by
Externí odkaz:
https://doaj.org/article/8f638549a7564b7693497fa502a4c1a6
Autor:
Sonia Coni, Silvia Maria Serrao, Zuleyha Nihan Yurtsever, Laura Di Magno, Rosa Bordone, Camilla Bertani, Valerio Licursi, Zaira Ianniello, Paola Infante, Marta Moretti, Marialaura Petroni, Francesca Guerrieri, Alessandro Fatica, Alberto Macone, Enrico De Smaele, Lucia Di Marcotullio, Giuseppe Giannini, Marella Maroder, Enzo Agostinelli, Gianluca Canettieri
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
ABSTRACT Eukaryotic Translation Initiation Factor 5A (EIF5A) is a translation factor regulated by hypusination, a unique posttranslational modification catalyzed by deoxyhypusine synthetase (DHPS) and deoxyhypusine hydroxylase (DOHH) starting from th
Externí odkaz:
https://doaj.org/article/fdcfae0429de479c97a55c2c58a84f8e
Autor:
Maria Teresa Di Martino, Stefania Meschini, Katia Scotlandi, Chiara Riganti, Enrico De Smaele, Francesca Zazzeroni, Massimo Donadelli, Carlo Leonetti, Michele Caraglia
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-11 (2020)
Abstract Molecular profiling of DNA and RNA has provided valuable new insights into the genetic basis of non-malignant and malignant disorders, as well as an increased understanding of basic mechanisms that regulate human disease. Recent technologica
Externí odkaz:
https://doaj.org/article/9de877396e9b457095db2f29af5d3a24