Light‐Responsive Nanoantennas Integrated into Nanoscale Metal–Organic Frameworks for Photothermal Drug Delivery

Autor: Manuela Cedrún‐Morales, Manuel Ceballos, Enrica Soprano, Giulia Zampini, Ester Polo, Beatriz Pelaz, Pablo del Pino

Publikováno v: Small Science, Vol 4, Iss 8, Pp n/a-n/a (2024)

Nanoscale metal–organic frameworks (NMOFs) exhibit unique properties for drug delivery, including ultrahigh storage capabilities, biocompatibility, biodegradability, and sustained release of encapsulated cargo. However, due to their localized elect

Externí odkaz: https://doaj.org/article/ddff9ac25e6c45efa1b0cd28af6a78a7

Identification and characterization of Cardiac Glycosides as senolytic compounds

Autor: Francisco Triana-Martínez, Pilar Picallos-Rabina, Sabela Da Silva-Álvarez, Federico Pietrocola, Susana Llanos, Verónica Rodilla, Enrica Soprano, Pablo Pedrosa, Alba Ferreirós, Marta Barradas, Fernanda Hernández-González, Marta Lalinde, Neus Prats, Cristina Bernadó, Patricia González, María Gómez, Maria P. Ikonomopoulou, Pablo J. Fernández-Marcos, Tomás García-Caballero, Pablo del Pino, Joaquín Arribas, Anxo Vidal, Miguel González-Barcia, Manuel Serrano, María I. Loza, Eduardo Domínguez, Manuel Collado

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)

Senolytic compounds have the ability to eliminate senescent cells from tissues and have been shown to be beneficial in various animal models of age-related diseases. Here the authors show that cardiac glycosides commonly used for heart diseases have

Externí odkaz: https://doaj.org/article/76f6dda146f1406681b8658e9fa1302e

Does conjugation strategy matter? Cetuximab-conjugated gold nanocages for targeting triple-negative breast cancer cells

Autor: Svetlana Avvakumova, A. Sánchez Iglesias, Elisabetta Galbiati, Fabio Corsi, Raffaele Allevi, L. Moretto, Maria Antonietta Rizzuto, Michela Bellini, Davide Prosperi, Miriam Colombo, Laura Pandolfi, Enrica Soprano

Publikováno v: Nanoscale Advances. 1:3626-3638

The efficient targeting of cancer cells depends on the success of obtaining the active targeting of overexpressed receptors. A very accurate design of nanoconjugates should be done via the selection of the conjugation strategy to achieve effective ta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ae7777dc8921d20a10d47ba2640913
https://doi.org/10.1039/c9na00241c

Contributors

Autor: Nicholas J. Abuid, Aitor Álvarez, Candace Benjamin, Agata Blasiak, Olivia Brohlin, Sean Burkitt, Jos Campbell, Carolina Carrillo-Carrión, Yahya Cheema, Andreina Chiu-Lam, Eun Ji Chung, Nathan D. Donahue, Natalie Dong, Mitsushita Doomra, Marco A. Downing, Omolola Eniola-Adefeso, Allen Eyler, Catherine A. Fromen, Eric Fuller, Tiffany RX. Gan, Jeremiah J. Gassensmith, Kerim M. Gattás-Asfura, Mengjie Gu, Hao Guo, Ankur Gupta, Dean Ho, Leaf Huang, Huang-Chiao Huang, Collin T. Inglut, Aaron J. Sorrin, Piyush K. Jain, Bader M. Jarai, Edward Kai-Hua Chow, Theodore Kee, Jeffrey Khong, Forrest M. Kievit, Jonathan Kin-Hun Lee, Emily L. Kolewe, Truong Thanh Lan Anh, Daniel J. LaShoto, Tram Le, Dao P. Le, Joanne C. Lee, Lorraine Leon, Barry J. Liang, John Andrew MacKay, Raquel Martínez, Tyler Maxwell, Michael McKenna, Samantha A. Meenach, Michael Mellas, Martina Migliavacca, Daniel Najafali, Elizabeth Nance, Steven M. Narum, María F. Navarro Poupard, Jiansheng Ng, Maria Gabriela Nogueira Campos, Beatriz Pelaz, Pablo del Pino, Ester Polo, Alexia M. Poulos, Nisha Raman, Carlos Rinaldi, Angelie Rivera-Rodriguez, Hanieh Safari, Swadeshmukul Santra, Shehaab Savliwala, Kacoli Sen, Nishan K. Shah, Sachit Shah, Arezoo Shahrivarkevishahi, Stephen Smith, Enrica Soprano, Jillian Stabile, Cherie L. Stabler, Zachary S. Stillman, Sara Tabandeh, Aria W. Tarudji, Marcus Threadcraft, Zon Thwin, Matthew Tirrell, Elisa A. Torrico Guzmán, Mythreyi Unni, Swapna Vaja, Jonathan Wang, Peter Wang, Zimeng Wang, Stefan Wilhelm, Jingru Xu, Wen Yang, Cristina Zavaleta, Yuan Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a1ea9c974bd29f0237e745c8d5a06de
https://doi.org/10.1016/b978-0-12-816662-8.01002-x

Identification and characterization of Cardiac Glycosides as senolytic compounds

Autor: Verónica Rodilla, Pablo J. Fernandez-Marcos, Marta Barradas, Manuel Collado, Marta Lalinde, Patricia González, Cristina Bernadó, Fernanda Hernández-González, Francisco Triana-Martínez, Joaquín Arribas, Maria P. Ikonomopoulou, Manuel Serrano, Miguel González-Barcia, Federico Pietrocola, María Elena Pardo Gómez, Eduardo Domínguez, Sabela Da Silva-Álvarez, Anxo Vidal, María Isabel Loza, Pablo del Pino, Pablo Pedrosa, Pilar Picallos-Rabina, Neus Prats, Alba Ferreirós, Tomás García-Caballero, Enrica Soprano, Susana Llanos

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
DOAJ-Articles
PubMed Central
Repisalud
Instituto de Salud Carlos III (ISCIII)

Compounds with specific cytotoxic activity in senescent cells, or senolytics, support the causal involvement of senescence in aging and offer therapeutic interventions. Here we report the identification of Cardiac Glycosides (CGs) as a family of comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f162bc58af9c967e2c989e5ae4413f1
https://doi.org/10.1038/s41467-019-12888-x