Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Enrica Flori"'
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 728 (2024)
Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor expressed in many tissues, including skin, where it is essential for maintaining skin barrier permeability, regulating cell proliferation/differentiation, and modulat
Externí odkaz:
https://doaj.org/article/73f4af5f9a944f16856505bab4f45d0e
Autor:
Enrica Flori, Alessia Cavallo, Sarah Mosca, Daniela Kovacs, Carlo Cota, Marco Zaccarini, Anna Di Nardo, Grazia Bottillo, Miriam Maiellaro, Emanuela Camera, Giorgia Cardinali
Publikováno v:
Cells, Vol 13, Iss 9, p 760 (2024)
Derangement of the epidermal barrier lipids and dysregulated immune responses are key pathogenic features of atopic dermatitis (AD). The Th2-type cytokines interleukin IL-4 and IL-13 play a prominent role in AD by activating the Janus Kinase/Signal T
Externí odkaz:
https://doaj.org/article/0710a2d66bad415fa24658a804adbef4
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Insulin affects metabolic processes in different organs, including the skin. The sebaceous gland (SG) is an important appendage in the skin, which responds to insulin-mediated signals, either directly or through the insulin growth factor 1 (IGF-1) ax
Externí odkaz:
https://doaj.org/article/c27b1d12477846b3a98497eebcd4d9f1
Autor:
Giorgia Cardinali, Daniela Kovacs, Sarah Mosca, Barbara Bellei, Enrica Flori, Aldo Morrone, Anna Maria Mileo, Vittoria Maresca
Publikováno v:
Cells, Vol 12, Iss 7, p 1099 (2023)
Stimulation of melanocytes and murine melanoma cells with αMSH plus the PI3K inhibitor LY294002 resulted in ROS increase, oxidative DNA damage, and pigment retention. We performed cellular and molecular biology assays (Western blot, FACS, immunofluo
Externí odkaz:
https://doaj.org/article/993c6cb220b14dc9b612695a2a85ae7c
Autor:
Enrica Flori, Sarah Mosca, Giorgia Cardinali, Stefania Briganti, Monica Ottaviani, Daniela Kovacs, Isabella Manni, Mauro Truglio, Arianna Mastrofrancesco, Marco Zaccarini, Carlo Cota, Giulia Piaggio, Mauro Picardo
Publikováno v:
Cells, Vol 12, Iss 7, p 1007 (2023)
Cutaneous squamous cell carcinoma (cSCC) is the most common UV-induced keratinocyte-derived cancer, and its progression is characterized by the epithelial–mesenchymal transition (EMT) process. We previously demonstrated that PPARγ activation by 2,
Externí odkaz:
https://doaj.org/article/926ad928d86c4a93aaf9ef3c4f9dcefe
Autor:
Enrica Flori, Arianna Mastrofrancesco, Sarah Mosca, Monica Ottaviani, Stefania Briganti, Giorgia Cardinali, Angela Filoni, Norma Cameli, Marco Zaccarini, Christos C. Zouboulis, Mauro Picardo
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103871- (2022)
Summary: Melasma is a hyperpigmentary disorder with photoaging features, whose manifestations appear on specific face areas, rich in sebaceous glands (SGs). To explore the SGs possible contribution to the onset, the expression of pro-melanogenic and
Externí odkaz:
https://doaj.org/article/8067f5c3a8b54b279d1598a060ea7d08
Autor:
Enrica Flori, Eleonora Rosati, Giorgia Cardinali, Daniela Kovacs, Barbara Bellei, Mauro Picardo, Vittoria Maresca
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-13 (2017)
Abstract Background The α-Melanocyte Stimulating Hormone (αMSH)/Melanocortin-1 receptor (MC1R) interaction promotes melanogenesis through the cAMP/PKA pathway. The direct induction of this pathway by Forskolin (FSK) is also known to enhance melanoc
Externí odkaz:
https://doaj.org/article/3f6fe0d7eb9346c4809224e431f1d85e
Autor:
Enrica Flori, Arianna Mastrofrancesco, Daniela Kovacs, Barbara Bellei, Stefania Briganti, Vittoria Maresca, Giorgia Cardinali, Mauro Picardo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Increasing attention is addressed to identify products able to enhance skin photoprotection and to prevent skin carcinogenesis. Several studies have demonstrated that the α-melanocyte stimulating hormone (αMSH), acting on a functional MC1R
Externí odkaz:
https://doaj.org/article/63811ae9102244098bb9b2a2d39ac52e
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104045 (2014)
Peroxisome proliferator-activated receptor gamma (PPARγ) may be involved in a key mechanism of the skin aging process, influencing several aspects related to the age-related degeneration of skin cells, including antioxidant unbalance. Therefore, we
Externí odkaz:
https://doaj.org/article/fce4613f01dc494fb4a772314d17b7a1
Autor:
Enrica Flori, Arianna Mastrofrancesco, Monica Ottaviani, Miriam Maiellaro, Christos C. Zouboulis, Emanuela Camera
Publikováno v:
Experimental Dermatology.