Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Enrica, Saponara"'
Autor:
Enrica Saponara, Rong Chen, Theresia Reding, Richard Zuellig, Darren C. Henstridge, Rolf Graf, Sabrina Sonda
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Identifying the fundamental molecular factors that drive weight gain even in the absence of hypercaloric food intake, is crucial to enable development of novel treatments for the global pandemic of obesity. Here we investigated both adipose tissue-sp
Externí odkaz:
https://doaj.org/article/1c3d92b7cfdd4497adb20f63c14e7f65
Autor:
Enrica Saponara, Carlos Penno, Vanessa Orsini, Zhong-Yi Wang, Audrey Fischer, Alexandra Aebi, Meztli L. Matadamas-Guzman, Virginie Brun, Benoit Fischer, Margaret Brousseau, Peter O'Donnell, Jonathan Turner, Alexandra Graff Meyer, Laura Bollepalli, Giovanni d’Ario, Guglielmo Roma, Walter Carbone, Stefano Annunziato, Michael Obrecht, Nicolau Beckmann, Chandra Saravanan, Arnaud Osmont, Philipp Tropberger, Shola M. Richards, Christel Genoud, Svenja Ley, Iwona Ksiazek, Florian Nigsch, Luigi M. Terracciano, Heiko S. Schadt, Tewis Bouwmeester, Jan S. Tchorz, Heinz Ruffner
Publikováno v:
The American journal of pathology.
The roof plate-specific spondin-leucine-rich repeat-containing G-protein-coupled receptor 4/5 (Lgr4/5)-zinc and ring finger 3/ring finger protein 43 module is a master regulator of hepatic Wnt/β-catenin signaling and metabolic zonation, but its impa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb7c1c4c6570641d2e5408b53b241d56
https://pubmed.ncbi.nlm.nih.gov/36410420
https://pubmed.ncbi.nlm.nih.gov/36410420
Autor:
Arnaud Osmont, Walter Carbone, Vanessa Orsini, Florian Nigsch, Jonathan J. Turner, Christel Genoud, Shola M Richards, Laura Bollepalli, Enrica Saponara, Svenja Ley, Zhong-Yi Wang, Giovanni d'Ario, Alexandra Aebi, Meztli L Matadamas Guzmán, Philipp Tropberger, Stefano Annunziato, Chandrassegar Saravanan, Benoit Fischer, Guglielmo Roma, Tewis Bouwmeester, Michael Obrecht, Jan S. Tchorz, Virginie Brun, Heinz Ruffner, Nicolau Beckmann, Carlos A. Penno, Margaret E. Brousseau, Peter O'Donnell, Alexandra Graff Meyer, Iwona Ksiazek, Luigi Terraciano
Background & AimsThe Rspo-Lgr4/5-Znrf3/Rnf43 module is a master regulator of hepatic Wnt/β-catenin signaling and metabolic zonation, but its impact on nonalcoholic fatty liver disease (NAFLD) remains unclear. We studied whether liver-specific loss o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a28cc1cd150989852141c4658c7ee558
https://doi.org/10.1101/2021.11.22.469602
https://doi.org/10.1101/2021.11.22.469602
Autor:
Andrew P. Hills, Stephen Myers, Sabrina Sonda, Domenico Salvatore, Rolf Graf, Monica Dentice, Theresia Reding, Ermanno Malagola, Rong Chen, Enrica Saponara, Marta Bombardo
Publikováno v:
The Journal of Pathology. 248:217-229
Proliferation of pancreatic acinar cells is a critical process in the pathophysiology of pancreatic diseases, because limited or defective proliferation is associated with organ dysfunction and patient morbidity. In this context, elucidating the sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062f61f1da6eeddadabadc1ba023a276
https://doi.org/10.1002/path.5247
https://doi.org/10.1002/path.5247
Autor:
Rong Chen, Enrica Saponara, Sabrina Sonda, Theresia Reding, Rolf Graf, Richard A. Zuellig, Darren C. Henstridge
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE, Vol 16, Iss 8, p e0255687 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255687 (2021)
PLoS ONE
Identifying the fundamental molecular factors that drive weight gain even in the absence of hypercaloric food intake, is crucial to enable development of novel treatments for the global pandemic of obesity. Here we investigated both adipose tissue-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b03f77b3eebce2a728c7b5ab122a3d7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357085/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357085/?tool=EBI
Autor:
Gitta Maria Seleznik, Rossella Parrotta, Sabrina Sonda, Paola Martinelli, Amedeo Caflisch, Francesco Baschieri, Rolf Graf, Irene Esposito, Michele Visentin, Marta Bombardo, Ermanno Malagola, Johanna Buschmann, Hesso Farhan, Rong Chen, Nathalie Borgeaud, Enrica Saponara
Publikováno v:
The Journal of Pathology. 246:352-365
Pancreatic ductal adenocarcinoma (PDAC), the primary cause of pancreatic cancer mortality, is poorly responsive to currently available interventions. Identifying new targets that drive PDAC formation and progression is critical to develop alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e17b0940939d0363e46511478fac94f6
https://doi.org/10.1002/path.5147
https://doi.org/10.1002/path.5147
Autor:
Rolf Graf, Ermanno Malagola, Andrew P. Hills, Marta Bombardo, Rong Chen, Sabrina Sonda, Enrica Saponara
Publikováno v:
Molecular Pharmacology. 94:793-801
Pancreatic fibrosis is the hallmark of chronic pancreatitis, a highly debilitating disease for which there is currently no cure. The key event at the basis of pancreatic fibrosis is the deposition of extracellular matrix proteins by activated pancrea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a850d1d4451fb7f485462874c0f7240b
https://doi.org/10.1124/mol.117.110924
https://doi.org/10.1124/mol.117.110924
Autor:
Enrica Saponara, Theresia Reding, Evans Quilichini, Anja Zabel, Rong Chen, Cécile Haumaitre, Gitta Maria Seleznik, Marta Bombardo, Ermanno Malagola, Rolf Graf, Sabrina Sonda
Publikováno v:
British Journal of Pharmacology. 174:3865-3880
Background and Purpose Pancreatitis is a common inflammation of the pancreas with rising incidence in many countries. Despite improvements in diagnostic techniques, the disease is associated with high risk of severe morbidity and mortality and there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c77c22bc756960e1ded6cd72ecefabd
https://doi.org/10.1111/bph.13984
https://doi.org/10.1111/bph.13984
Autor:
Rolf Graf, Enrica Saponara, Michael Linecker, Bostjan Humar, Magda Langiewicz, Andrea Schlegel, Pieter Borger, Pierre A. Clavien
Publikováno v:
Journal of Hepatology. 66:560-570
ALPPS, a novel two-staged approach for the surgical removal of large/multiple liver tumors, combines portal vein ligation (PVL) with parenchymal transection. This causes acceleration of compensatory liver growth, enabling faster and more extensive tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26245d34cc047ff087d0a40269892a25
https://doi.org/10.1016/j.jhep.2016.10.014
https://doi.org/10.1016/j.jhep.2016.10.014
Autor:
Enrica, Saponara, Michele, Visentin, Francesco, Baschieri, Gitta, Seleznik, Paola, Martinelli, Irene, Esposito, Johanna, Buschmann, Rong, Chen, Rossella, Parrotta, Nathalie, Borgeaud, Marta, Bombardo, Ermanno, Malagola, Amedeo, Caflisch, Hesso, Farhan, Rolf, Graf, Sabrina, Sonda
Publikováno v:
The Journal of pathology. 246(3)
Pancreatic ductal adenocarcinoma (PDAC), which is the primary cause of pancreatic cancer mortality, is poorly responsive to currently available interventions. Identifying new targets that drive PDAC formation and progression is critical for developin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::547c856e3ab0a7eba52fd5228bc1c4b1
https://pubmed.ncbi.nlm.nih.gov/30058725
https://pubmed.ncbi.nlm.nih.gov/30058725