Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Enric Mocholi"'
Autor:
Renata Vieira de Sá, Emma Sudria-Lopez, Marta Cañizares Luna, Oliver Harschnitz, Dianne M. A. van den Heuvel, Sandra Kling, Danielle Vonk, Henk-Jan Westeneng, Henk Karst, Lauri Bloemenkamp, Suzy Varderidou-Minasian, Domino K. Schlegel, Mayte Mars, Mark H. Broekhoven, Nicky C. H. van Kronenburg, Youri Adolfs, Vamshidhar R. Vangoor, Rianne de Jongh, Tijana Ljubikj, Lianne Peeters, Sabine Seeler, Enric Mocholi, Onur Basak, David Gordon, Fabrizio Giuliani, Tessa Verhoeff, Giel Korsten, Teresa Calafat Pla, Morten T. Venø, Jørgen Kjems, Kevin Talbot, Michael A. van Es, Jan H. Veldink, Leonard H. van den Berg, Pavol Zelina, R. Jeroen Pasterkamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Intermediate-length repeat expansions in ATAXIN-2 (ATXN2) are the strongest genetic risk factor for amyotrophic lateral sclerosis (ALS). At the molecular level, ATXN2 intermediate expansions enhance TDP-43 toxicity and pathology. However, wh
Externí odkaz:
https://doaj.org/article/f542924285bc411ab2ef82b8bba3d188
Autor:
Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110072- (2024)
Summary: The intestine is vulnerable to chemotherapy-induced damage due to the high rate of intestinal epithelial cell (IEC) proliferation. We have developed a human intestinal organoid-based 3D model system to study the direct effect of chemotherapy
Externí odkaz:
https://doaj.org/article/b237740e0ce446bdbb6f4231e7e5bc68
Autor:
Enric Mocholi, Laura Russo, Keshav Gopal, Andrew G. Ramstead, Sophia M. Hochrein, Harmjan R. Vos, Geert Geeven, Adeolu O. Adegoke, Anna Hoekstra, Robert M. van Es, Jose Ramos Pittol, Sebastian Vastert, Jared Rutter, Timothy Radstake, Jorg van Loosdregt, Celia Berkers, Michal Mokry, Colin C. Anderson, Ryan M. O’Connell, Martin Vaeth, John Ussher, Boudewijn M.T. Burgering, Paul J. Coffer
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112583- (2023)
Summary: Upon antigen-specific T cell receptor (TCR) engagement, human CD4+ T cells proliferate and differentiate, a process associated with rapid transcriptional changes and metabolic reprogramming. Here, we show that the generation of extramitochon
Externí odkaz:
https://doaj.org/article/942f229d67194e4a9cd020cad65978f5
Autor:
Albanyan, Saleh, Giles, Rachel H., Gimeno, Enric Mocholi, Silver, Josh, Murphy, Jillian, Faghfoury, Hanna, Morel, Chantal F., Machado, Jerry, Kim, Raymond H.
Publikováno v:
In European Journal of Medical Genetics March 2019 62(3):177-181
PDF file - 625K, NFAT1-deficient CD4+ T cells are resistant to soluble peptide-induced anergy in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2753cb0444e077fd1489e6e90116538e
https://doi.org/10.1158/0008-5472.22392050
https://doi.org/10.1158/0008-5472.22392050
Chemotherapy-Induced Intestinal Epithelial Damage Can Attract T Cells and Modulate T Cell Activation
Autor:
Alessandro Cutilli, Suze A. Jansen, Marliek Hoesel, Coco C de Koning, Stefan Nierkens, Alan M. Hanash, Enric Mocholi, Paul James Coffer, Caroline Ariane Lindemans
Publikováno v:
Transplantation and Cellular Therapy. 29:S244
Autor:
Enric Mocholi, Laura Russo, Keshav Gopal, Andrew Ramstead, Sophia M. Hochrein, HarmJan Vos, Geert Geeven, Adeolu Adegoke, Anna Hoekstra, Robert van Es, José Ramos Pittol, Sebastiaan Vastert, Jared Rutter, Timothy Radstake, Jorg van Loosdregt, Celia Berkers, Michal Mokry, Colin Anderson, Ryan O'Connell, Martin Vaeth, John Ussher, Boudewijn Burgering, Paul Coffer
Upon antigen-specific T Cell Receptor (TCR) engagement, human CD4+ T cells proliferate and differentiate, a process associated with rapid transcriptional changes and metabolic reprogramming. Here, we show that generation of extra-mitochondrial pyruva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b71b2a137c6e61ad219ab6d4149ac04
https://doi.org/10.21203/rs.3.rs-1324599/v1
https://doi.org/10.21203/rs.3.rs-1324599/v1
Autor:
Chantal F Morel, Saleh Albanyan, Jillian Murphy, Rachel H. Giles, Enric Mocholi Gimeno, Raymond H. Kim, Hanna Faghfoury, Jerry Machado, Josh Silver
Publikováno v:
European Journal of Medical Genetics, 62(3), 177. Elsevier Masson SAS
Von Hippel-Lindau (VHL) disease is a hereditary tumor syndrome in which carriers are at an increased risk of developing a variety of tumors in multiple organ systems. A clinical diagnosis of VHL is determined by the presence of specific clinical mani
Autor:
Bas Vastert, Paul J. Coffer, Michal Mokry, Boudewijn M.T. Burgering, Enric Mocholi, Laura Russo
Publikováno v:
The FASEB Journal. 33