Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Enric Mocholí"'
Autor:
Cristina Cueto-Ureña, Enric Mocholí, Josep Escrivá-Fernández, Susana González-Granero, Sabina Sánchez-Hernández, Amalia Solana-Orts, Begoña Ballester-Lurbe, Karim Benabdellah, Rosa M. Guasch, José Manuel García-Verdugo, Francisco Martín, Paul J. Coffer, Ignacio Pérez-Roger, Enric Poch
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Autophagy is a highly conserved process that mediates the targeting and degradation of intracellular components to lysosomes, contributing to the maintenance of cellular homeostasis and to obtaining energy, which ensures viability under stress condit
Externí odkaz:
https://doaj.org/article/7de0449f54f5452689bd32359d3d685e
Autor:
Enric Mocholí, Begoña Ballester-Lurbe, Gloria Arqué, Enric Poch, Blanca Peris, Consuelo Guerri, Mara Dierssen, Rosa M Guasch, José Terrado, Ignacio Pérez-Roger
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19236 (2011)
Rnd proteins are a subfamily of Rho GTPases involved in the control of actin cytoskeleton dynamics and other cell functions such as motility, proliferation and survival. Unlike other members of the Rho family, Rnd proteins lack GTPase activity and th
Externí odkaz:
https://doaj.org/article/1ba4100a36f144729fd2edde32470114
Autor:
Albanyan, Saleh, Giles, Rachel H., Gimeno, Enric Mocholi, Silver, Josh, Murphy, Jillian, Faghfoury, Hanna, Morel, Chantal F., Machado, Jerry, Kim, Raymond H.
Publikováno v:
In European Journal of Medical Genetics March 2019 62(3):177-181
Autor:
Renata Vieira de Sá, Emma Sudria-Lopez, Marta Cañizares Luna, Oliver Harschnitz, Dianne M. A. van den Heuvel, Sandra Kling, Danielle Vonk, Henk-Jan Westeneng, Henk Karst, Lauri Bloemenkamp, Suzy Varderidou-Minasian, Domino K. Schlegel, Mayte Mars, Mark H. Broekhoven, Nicky C. H. van Kronenburg, Youri Adolfs, Vamshidhar R. Vangoor, Rianne de Jongh, Tijana Ljubikj, Lianne Peeters, Sabine Seeler, Enric Mocholi, Onur Basak, David Gordon, Fabrizio Giuliani, Tessa Verhoeff, Giel Korsten, Teresa Calafat Pla, Morten T. Venø, Jørgen Kjems, Kevin Talbot, Michael A. van Es, Jan H. Veldink, Leonard H. van den Berg, Pavol Zelina, R. Jeroen Pasterkamp
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Intermediate-length repeat expansions in ATAXIN-2 (ATXN2) are the strongest genetic risk factor for amyotrophic lateral sclerosis (ALS). At the molecular level, ATXN2 intermediate expansions enhance TDP-43 toxicity and pathology. However, wh
Externí odkaz:
https://doaj.org/article/f542924285bc411ab2ef82b8bba3d188
Autor:
Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110072- (2024)
Summary: The intestine is vulnerable to chemotherapy-induced damage due to the high rate of intestinal epithelial cell (IEC) proliferation. We have developed a human intestinal organoid-based 3D model system to study the direct effect of chemotherapy
Externí odkaz:
https://doaj.org/article/b237740e0ce446bdbb6f4231e7e5bc68
Autor:
Enric Mocholi, Laura Russo, Keshav Gopal, Andrew G. Ramstead, Sophia M. Hochrein, Harmjan R. Vos, Geert Geeven, Adeolu O. Adegoke, Anna Hoekstra, Robert M. van Es, Jose Ramos Pittol, Sebastian Vastert, Jared Rutter, Timothy Radstake, Jorg van Loosdregt, Celia Berkers, Michal Mokry, Colin C. Anderson, Ryan M. O’Connell, Martin Vaeth, John Ussher, Boudewijn M.T. Burgering, Paul J. Coffer
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112583- (2023)
Summary: Upon antigen-specific T cell receptor (TCR) engagement, human CD4+ T cells proliferate and differentiate, a process associated with rapid transcriptional changes and metabolic reprogramming. Here, we show that the generation of extramitochon
Externí odkaz:
https://doaj.org/article/942f229d67194e4a9cd020cad65978f5