Výsledky vyhledávání - "Enosh M. Askenasy"

Akademický článek

Effector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD mice.

Autor: Ayelet Kaminitz, Esma S Yolcu, Enosh M Askenasy, Jerry Stein, Isaac Yaniv, Haval Shirwan, Nadir Askenasy

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21630 (2011)

BACKGROUND: Disturbed peripheral negative regulation might contribute to evolution of autoimmune insulitis in type 1 diabetes. This study evaluates the sensitivity of naïve/effector (Teff) and regulatory T cells (Treg) to activation-induced cell dea

Externí odkaz: https://doaj.org/article/550adadd10774031a12a319ee3e25e7d

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Akademický článek

Apoptosis of purified CD4+ T cell subsets is dominated by cytokine deprivation and absence of other cells in new onset diabetic NOD mice.

Autor: Ayelet Kaminitz, Enosh M Askenasy, Isaac Yaniv, Jerry Stein, Nadir Askenasy

Publikováno v: PLoS ONE, Vol 5, Iss 12, p e15684 (2010)

BACKGROUND: Regulatory T cells (Treg) play a significant role in immune homeostasis and self-tolerance. Excessive sensitivity of isolated Treg to apoptosis has been demonstrated in NOD mice and humans suffering of type 1 diabetes, suggesting a possib

Externí odkaz: https://doaj.org/article/02c36c75efed4218850fbfc63f54256d

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Depletion of Naïve Lymphocytes with Fas Ligand Ex Vivo Prevents Graft-versus-Host Disease without Impairing T Cell Support of Engraftment or Graft-versus-Tumor Activity

Autor: Isaac Yaniv, Keren Mizrahi, Enosh M. Askenasy, Jerry Stein, Nadir Askenasy, Shifra Ash

Publikováno v: Biology of Blood and Marrow Transplantation. 19(2):185-195

Graft-versus-host disease (GVHD) can be prevented by Fas-mediated selective depletion of host-sensitized donor lymphocytes ex vivo. We tested the hypothesis that Fas-mediated depletion of lymphocytes in the absence of host-specific antigenic stimulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0922d41cfb9b1197f95ff6db37d201

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Is autoimmune diabetes caused by aberrant immune activity or defective suppression of physiological self-reactivity?

Autor: Nadir Askenasy, Enosh M. Askenasy

Publikováno v: Autoimmunity reviews. 12(5)

Two competing hypotheses are proposed to cause autoimmunity: evasion of a sporadic self-reactive clone from immune surveillance and ineffective suppression of autoreactive clones that arise physiologically. We question the relevance of these hypothes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8207fc6ec11f6f24cd017815921e9d59
https://pubmed.ncbi.nlm.nih.gov/23277162

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Effector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD mice

Autor: Esma S. Yolcu, Jerry Stein, Ayelet Kaminitz, Haval Shirwan, Nadir Askenasy, Isaac Yaniv, Enosh M. Askenasy

Publikováno v: PLoS ONE, Vol 6, Iss 6, p e21630 (2011)
PLoS ONE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039e7047915dc0ef2b1ef7135f3c8de2
http://europepmc.org/articles/PMC3124542?pdf=render

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Does lymphopenia preclude restoration of immune homeostasis? The particular case of type 1 diabetes

Autor: Nadir Askenasy, Jean-Jaques Askenasy, Enosh M. Askenasy

Publikováno v: Autoimmunity reviews. 9(10)

Induction of hematopoietic chimerism initiates tolerizing processes that often restore control over autoimmune reactions: graft versus autoimmunity reaction. In view of the limited capacity of autologous bone marrow transplants and some cases of pers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0b688b2c455212792e634fe6aebf17
https://pubmed.ncbi.nlm.nih.gov/20624693

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