Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Enol López"'
Publikováno v:
Marine Drugs, Vol 22, Iss 6, p 253 (2024)
Transition metal catalysis has contributed to the discovery of novel methodologies and the preparation of natural products, as well as new chances to increase the chemical space in drug discovery programs. In the case of marine drugs, this strategy h
Externí odkaz:
https://doaj.org/article/c9be70400e9346eabbe7305703fa7fc1
Autor:
Laura F. Peña, Paula González-Andrés, Lucía G. Parte, Raúl Escribano, Javier Guerra, Asunción Barbero, Enol López
Publikováno v:
Marine Drugs, Vol 21, Iss 7, p 402 (2023)
In this perspective, we showcase the benefits of continuous flow chemistry and photochemistry and how these valuable tools have contributed to the synthesis of organic scaffolds from the marine environment. These technologies have not only facilitate
Externí odkaz:
https://doaj.org/article/1a8050f0e8004c539d6f1db81d454d8f
Publikováno v:
Molecules, Vol 28, Iss 7, p 3080 (2023)
A convenient regioselective synthesis of allyl- and vinylsilyl alcohols, from a common precursor, was described, by selecting the appropriate reaction conditions. Allyl- and vinylsilyl alcohols were tested in silyl-Prins cyclizations for the preparat
Externí odkaz:
https://doaj.org/article/40663a2d2d2842019edd3b5809c59740
Publikováno v:
Marine Drugs, Vol 21, Iss 1, p 37 (2022)
Coumarin and its derivatives have significantly attracted the attention of medicinal chemists and chemical biologists due to their huge range of biological, and in particular, pharmacological properties. Interesting families of coumarins have been fo
Externí odkaz:
https://doaj.org/article/bc9198322414460e84c20a47f8bf9bc4
Publikováno v:
Molecules, Vol 23, Iss 6, p 1335 (2018)
The reaction of para-hydroxybenzyl alcohols with ferrocene in the presence of a catalytic amount of InCl3 provided ferrocenyl phenol derivatives, an interesting class of organometallic compounds with potential applications in medicinal chemistry. Thi
Externí odkaz:
https://doaj.org/article/169a356f638c4b6aa366c2df8ce16a67
Publikováno v:
Flow and Microreactor Technology in Medicinal Chemistry. :67-102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c613c72e6039bf880460207765065529
https://doi.org/10.1002/9783527824595.ch3
https://doi.org/10.1002/9783527824595.ch3
Autor:
Brenda Pijper, Raúl Martín, Alberto J. Huertas-Alonso, Maria Lourdes Linares, Enol López, Josep Llaveria, Ángel Díaz-Ortiz, Darren J. Dixon, Antonio de la Hoz, Jesús Alcázar
Publikováno v:
Organic Letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2130e47c0984f584bb262a821f1a4f54
https://doi.org/10.1021/acs.orglett.3c01390
https://doi.org/10.1021/acs.orglett.3c01390
Autor:
Jesús Alcázar, Adrian P. Dobbs, Antonio de la Hoz, Raúl Martín, Angel Díaz-Ortiz, Alessia Petti, Enol López, Carlo G. W. van Melis, Kevin Lam
Publikováno v:
Advanced Synthesis & Catalysis. 363:4521-4525
A new and practical two-step transition metal-free methodology for the C(sp3)-C(sp3) functionalisation of saturated N-heterocyclic systems is disclosed. First, aminal derivatives are generated through the anodic oxidation of readily accessible carbox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc6b0b955dd0ec49f42bcae15c017e4
https://doi.org/10.1002/adsc.202100749
https://doi.org/10.1002/adsc.202100749
Publikováno v:
Future Medicinal Chemistry. 12:1547-1563
This perspective scrutinizes flow chemistry as a useful tool for medicinal chemists to expand the current chemical capabilities in drug discovery. This technology has demonstrated his value not only for the traditional reactions used in Pharma for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72a2bdbc94c9419adc347ed3e7e20dd
https://doi.org/10.4155/fmc-2020-0075
https://doi.org/10.4155/fmc-2020-0075
Autor:
Eduardo Palao, Iván Torres-Moya, Antonio de la Hoz, Angel Díaz-Ortiz, Jesús Alcázar, Enol López
Publikováno v:
RUIdeRA. Repositorio Institucional de la UCLM
instname
instname
Formation of all-carbon-substituted quaternary carbons is a key challenge in organic and medicinal chemistry. We report a cobalt-catalyzed C(sp3)–C(sp3) cross-coupling that allows for the introduction of benzyl, heteroarylmethylzinc and allyl group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23193928b503312d42d1c8ad6068ed82
https://doi.org/10.1039/d0cc02734k
https://doi.org/10.1039/d0cc02734k