Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Enno Klussmann"'
Autor:
Sandrine Baltzer, Timur Bulatov, Christopher Schmied, Andreas Krämer, Benedict-Tilman Berger, Andreas Oder, Ryan Walker-Gray, Christin Kuschke, Kerstin Zühlke, Jenny Eichhorst, Martin Lehmann, Stefan Knapp, John Weston, Jens Peter von Kries, Roderich D. Süssmuth, Enno Klussmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 2, p 763 (2022)
The cAMP-dependent aquaporin-2 (AQP2) redistribution from intracellular vesicles into the plasma membrane of renal collecting duct principal cells induces water reabsorption and fine-tunes body water homeostasis. However, the mechanisms controlling t
Externí odkaz:
https://doaj.org/article/be752154d8be482f938e4f7c5fb62df4
Autor:
Xiaocheng Zhao, Pavel Nedvetsky, Fabio Stanchi, Anne-Clemence Vion, Oliver Popp, Kerstin Zühlke, Gunnar Dittmar, Enno Klussmann, Holger Gerhardt
Publikováno v:
eLife, Vol 9 (2020)
Externí odkaz:
https://doaj.org/article/f50788c63ebb4063b63669ca3c6bad5e
Autor:
Xiaocheng Zhao, Pavel Nedvetsky, Fabio Stanchi, Anne-Clemence Vion, Oliver Popp, Kerstin Zühlke, Gunnar Dittmar, Enno Klussmann, Holger Gerhardt
Publikováno v:
eLife, Vol 8 (2019)
The cAMP-dependent protein kinase A (PKA) regulates various cellular functions in health and disease. In endothelial cells PKA activity promotes vessel maturation and limits tip cell formation. Here, we used a chemical genetic screen to identify endo
Externí odkaz:
https://doaj.org/article/d866cab8e84a4592975aa952d912b1a6
Autor:
Rebecca L. Eccles, Maciej T. Czajkowski, Carolin Barth, Paul Markus Müller, Erik McShane, Stephan Grunwald, Patrick Beaudette, Nora Mecklenburg, Rudolf Volkmer, Kerstin Zühlke, Gunnar Dittmar, Matthias Selbach, Annette Hammes, Oliver Daumke, Enno Klussmann, Sylvie Urbé, Oliver Rocks
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Protein kinase A (PKA) is a key mediator of cyclic AMP signalling. Here, Eccles et al. show that ARHGAP36 antagonizes PKA by acting as a kinase inhibitor and targeting the catalytic subunit for endolysosomal degradation, thus reducing sensitivity of
Externí odkaz:
https://doaj.org/article/4b603724ee39452aa970f9812ba07050
Autor:
Alessandro Dema, Dörte Faust, Katina Lazarow, Marc Wippich, Martin Neuenschwander, Kerstin Zühlke, Andrea Geelhaar, Tamara Pallien, Eileen Hallscheidt, Jenny Eichhorst, Burkhard Wiesner, Hana Černecká, Oliver Popp, Philipp Mertins, Gunnar Dittmar, Jens Peter von Kries, Enno Klussmann
Publikováno v:
Cells, Vol 9, Iss 3, p 673 (2020)
Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2). The hormone binds to vasopressin V2 receptors (V2R) on the surface of the cells and stimula
Externí odkaz:
https://doaj.org/article/2e53df9d47594aa78197c2dae41ffcc8
Autor:
Katharina Schrade, Jessica Tröger, Adeeb Eldahshan, Kerstin Zühlke, Kamal R Abdul Azeez, Jonathan M Elkins, Martin Neuenschwander, Andreas Oder, Mohamed Elkewedi, Sarah Jaksch, Karsten Andrae, Jinliang Li, Joao Fernandes, Paul Markus Müller, Stephan Grunwald, Stephen F Marino, Tanja Vukićević, Jenny Eichhorst, Burkhard Wiesner, Marcus Weber, Michael Kapiloff, Oliver Rocks, Oliver Daumke, Thomas Wieland, Stefan Knapp, Jens Peter von Kries, Enno Klussmann
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191423 (2018)
Stimulation of renal collecting duct principal cells with antidiuretic hormone (arginine-vasopressin, AVP) results in inhibition of the small GTPase RhoA and the enrichment of the water channel aquaporin-2 (AQP2) in the plasma membrane. The membrane
Externí odkaz:
https://doaj.org/article/90f46ed5dd9245e28b25eb7c6c87fe03
Autor:
Maria Ercu, Enno Klussmann
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 5, Iss 1, p 14 (2018)
A-kinase anchoring proteins (AKAPs) and cyclic nucleotide phosphodiesterases (PDEs) are essential enzymes in the cyclic adenosine 3’-5’ monophosphate (cAMP) signaling cascade. They establish local cAMP pools by controlling the intensity, duration
Externí odkaz:
https://doaj.org/article/4cf37a04ead041fcb177d6cd7907bd5c
Publikováno v:
Hypertension. 80:1171-1179
Hypertension with brachydactyly (HTNB) represents an autosomal dominant form of hypertension. It is a rare syndrome, in which the blood pressure can rise by more than 50 mmHg. If untreated, the patients die of stroke by the age of 50 years. In HTNB,
Autor:
Enno Klussmann
Publikováno v:
Kidney International. 103:458-460
Autor:
Gitte R. Hinrichs, Sandrine Baltzer, Tamara Pallien, Per Svenningsen, Emil B. Dalgaard, Jens Michael Hertz, Claus Bistrup, Boye L. Jensen, Enno Klussmann
Publikováno v:
Kidney International Reports. 7:2289-2294