Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Enni, Markkanen"'
Autor:
Anne-Laure Leblond, Birgit Helmchen, Maliki Ankavay, Daniela Lenggenhager, Jasna Jetzer, Fritjof Helmchen, Hueseyin Yurtsever, Rossella Parrotta, Marc E. Healy, Amiskwia Pöschel, Enni Markkanen, Nasser Semmo, Martin Ferrié, Laurence Cocquerel, Harald Seeger, Helmut Hopfer, Beat Müllhaupt, Jérôme Gouttenoire, Darius Moradpour, Ariana Gaspert, Achim Weber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Hepatitis E virus (HEV) infection, one of the most common forms of hepatitis worldwide, is often associated with extrahepatic, particularly renal, manifestations. However, the underlying mechanisms are incompletely understood. Here, we repor
Externí odkaz:
https://doaj.org/article/2e0acd6efb7748d6ab4fa79b0d50a92c
Autor:
Patricia Beer, Chantal Pauli, Martina Haberecker, Paula Grest, Erin Beebe, Daniel Fuchs, Enni Markkanen, Christiane Krudewig, Mirja Christine Nolff
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionComplete surgical tumor resection is paramount in the management of soft tissue sarcoma (STS) in humans, dogs, and cats alike. Near-infrared targeted tracers for fluorescence-guided surgery (FGS) could facilitate intraoperative visualizat
Externí odkaz:
https://doaj.org/article/28e4155deaed4c03bc20cce0eb443212
Autor:
Flavia S. Mueller, René Amport, Tina Notter, Sina M. Schalbetter, Han-Yu Lin, Zuzana Garajova, Parisa Amini, Ulrike Weber-Stadlbauer, Enni Markkanen
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Neuropsychiatric disorders, such as schizophrenia (SZ) and autism spectrum disorder (ASD), are common, multi-factorial and multi-symptomatic disorders. Ample evidence implicates oxidative stress, deficient repair of oxidative DNA
Externí odkaz:
https://doaj.org/article/c83009d44d3b4aa5b2786c4c265575f6
Autor:
Erin Beebe, Amiskwia Pöschel, Laura Kunz, Witold Wolski, Zahra Motamed, Daniela Meier, Franco Guscetti, Mirja C. Nolff, Enni Markkanen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100858- (2023)
Fibrosarcoma (FSA) are rare soft tissue tumors that display aggressive local behavior and invasive growth leading to high rates of tumor recurrence. While the low incidence in humans hampers detailed understanding of the disease, FSA are frequent in
Externí odkaz:
https://doaj.org/article/538b0bbfdad1451baa3134b8ae48a32f
Autor:
Amiskwia Pöschel, Erin Beebe, Laura Kunz, Parisa Amini, Franco Guscetti, Alexandra Malbon, Enni Markkanen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 4, Pp 400-412 (2021)
Cancer-associated stroma (CAS) profoundly influences progression of tumors including mammary carcinoma (mCA). Canine simple mCA represent relevant models of human mCA, notably also with respect to CAS. While transcriptomic changes in CAS of mCA are w
Externí odkaz:
https://doaj.org/article/caa9ba1a07734671983ca27b51eb4029
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 778-788 (2020)
Spontaneously occurring canine oral squamous cell carcinomas (COSCC) are viewed as a useful model for human head and neck squamous cell carcinomas (HNSCC). To date however, the molecular basis of COSCC remains poorly understood. To identify changes p
Externí odkaz:
https://doaj.org/article/1f2b02cf1ca24561875fbaf80a95e368
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-15 (2020)
Abstract Background Base-excision repair (BER) is a central DNA repair mechanism responsible for the maintenance of genome integrity. Accordingly, BER defects have been implicated in cancer, presumably by precipitating cellular transformation through
Externí odkaz:
https://doaj.org/article/51cb9edc35614f9dbfb4cef1fbedf6ed
Publikováno v:
Bio-Protocol, Vol 11, Iss 22 (2021)
Maintenance of DNA integrity is of pivotal importance for cells to circumvent detrimental processes that can ultimately lead to the development of various diseases. In the face of a plethora of endogenous and exogenous DNA damaging agents, cells have
Externí odkaz:
https://doaj.org/article/6c9f919248704914a319a41bc445086f
Publikováno v:
Bio-Protocol, Vol 11, Iss 16 (2021)
Maintenance of DNA integrity is of pivotal importance for cells to circumvent detrimental processes that can ultimately lead to the development of various diseases. In the face of a plethora of endogenous and exogenous DNA-damaging agents, cells have
Externí odkaz:
https://doaj.org/article/bf94d90dc48f4de58faef4710048f13b
Autor:
Enni Markkanen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Spontaneous canine simple mammary tumors (CMTs) are often viewed as models of human breast cancer. Cancer-associated stroma (CAS) is central for initiation and progression of human cancer, and is likely to play a key role in canine tumors as well. Un
Externí odkaz:
https://doaj.org/article/2c47f455057e41d282c7e1d979a77b4a