Microwave-assisted synthesis of chromeno[2,3-d] pyrimidinone derivatives

Autor: Aida Chaker, Ennaji Najahi, Françoise Nepveu, Fakher Chanchoub

Publikováno v: Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S3040-S3047 (2017)

New series of 10-anilino-9-alkyl-12-aryl-10,12-dihydro-11H-benzo[5,6] chromeno [2,3-d]pyrimidin-11-ones 5(a–e) and 9-anilino-10-alkyl-7-aryl-7,9-dihydro-8H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-ones 6(a–f) were prepared in three steps with microwa

Externí odkaz: https://doaj.org/article/14315ad98e7d42248dbc4b5d524c96cc

Synthesis of 6-Amino-5-cyano-1,4-disubstituted-2(1H)-Pyrimidinones via Copper-(I)-catalyzed Alkyne-azide ‘Click Chemistry’ and Their Reactivity

Autor: Fethi Zribi, Romain Duval, Fakher Chabchoub, Françoise Nepveu, Ennaji Najahi, Jan Sudor

Publikováno v: Molecules, Vol 15, Iss 12, Pp 8841-8855 (2010)

In this paper we present the room temperature synthesis of a novel serie of 1,4-disubstituted-1,2,3-triazoles 4a-l by employing the (3 + 2) cycloaddition reaction of pyrimidinones containing alkyne functions with different model azides in the presenc

Externí odkaz: https://doaj.org/article/b21500e3bf604470b7ab65484bc18760

The Clitocybins and 2-Substituted-Isoindolin-1-Ones: Synthesis and in Vitro Antimycobacterial Activities

Autor: Ennaji Najahi, Pierre Perio, Etienne Hollande, Françoise Nepveu, Rym Abidi, Amani Mejai, Maria Rosalia Pasca, Nambinina V. Rakotoarivelo

Publikováno v: JOURNAL OF ADVANCES IN CHEMISTRY. 16:5387-5394

Despite strong indications of antimycobacterial activities for clitocybins reported since 1945, no reports linking chemical structure and activity have been reported in the literature since then. In this study, we synthesized some clitocybin derivati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4c37cb73f276ee1d47fdea75696cbf0
https://doi.org/10.24297/jac.v16i0.8476

New 3-substituted-2,1-benzisoxazoles: Synthesis and antimicrobial activities

Autor: Fakher Chabchoub, Michel Treilhou, Ennaji Najahi, Aida Chaker, Nathan Téné, Alexis Valentin, Françoise Nepveu, Olivier Chatriant

Publikováno v: Arabian Journal of Chemistry
Arabian Journal of Chemistry, 2017, 10 (Supplement 2), pp.S2464-S2470. ⟨10.1016/j.arabjc.2013.09.011⟩
Arabian Journal of Chemistry, Elsevier, 2017, 10 (Supplement 2), pp.S2464-S2470. ⟨10.1016/j.arabjc.2013.09.011⟩
Arabian Journal of Chemistry, Vol 10, Iss S2, Pp S2464-S2470 (2017)

A new series of 3-substituted-2,1-benzisoxazoles (anthranils) were prepared by different methods and characterized by spectroscopic methods and mass spectrometry. These 2,1-benzisoxazoles were tested in vitro for their antiplasmodial activity on a ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17558baa6092b3840b8c6699f6e5f31
https://hal.science/hal-02417861/file/ChakerAida_NajahiEnnaji_ChatriantOlivier_etal_2017.pdf

ISOINDOLINOTRIAZOLE DERIVATIVES: SYNTHESIS BY THE AZIDE-ALKYNE CYCLOADDITION CLICK CHEMISTRY

Autor: Françoise Nepveu, Ennaji Najahi, Etienne Hollande, Nambinina V. Rakotoarivelo, Pierre Perio

Publikováno v: JOURNAL OF ADVANCES IN CHEMISTRY. 10:2937-2943

A novel series of isoindolinotriazole derivatives with different substituents in the triazole moiety were synthesized via copper-catalyzed cycloaddition (CuAAC) click chemistry between 2-(meta- or para-ethynylphenyl)-4,6-dimethoxyisoindolin-1-ones an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a50f9121da832d343bae8183108d7827
https://doi.org/10.24297/jac.v10i7.6797