Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Enna, Manhardt"'
Autor:
Bo Yu, Congzhou Liu, Sean C Proll, Enna Manhardt, Shuying Liang, Sujatha Srinivasan, Elizabeth Swisher, David N Fredricks
Publikováno v:
eLife, Vol 12 (2024)
Investigating the human fallopian tube (FT) microbiota has significant implications for understanding the pathogenesis of ovarian cancer (OC). In this large prospective study, we collected swabs intraoperatively from the FT and other surgical sites a
Externí odkaz:
https://doaj.org/article/c86c2900745b42c9a1f533bd053d8f33
Autor:
Talayeh S. Ghezelayagh, Brendan F. Kohrn, Jeanne Fredrickson, Enna Manhardt, Marc R. Radke, Ronit Katz, Heidi J. Gray, Renata R. Urban, Kathryn P. Pennington, John B. Liao, Kemi M. Doll, Elise J. Simons, Jennifer K. Burzawa, Barbara A. Goff, Paul Speiser, Elizabeth M. Swisher, Barbara M. Norquist, Rosa Ana Risques
Publikováno v:
Cancer Research Communications. 2:1282-1292
Current screening methods for ovarian cancer have failed to demonstrate a significant reduction in mortality. Uterine lavage combined with TP53 ultradeep sequencing for the detection of disseminated ovarian cancer cells has emerged as a promising too
Autor:
Talayeh S, Ghezelayagh, Brendan F, Kohrn, Jeanne, Fredrickson, Enna, Manhardt, Marc R, Radke, Ronit, Katz, Heidi J, Gray, Renata R, Urban, Kathryn P, Pennington, John B, Liao, Kemi M, Doll, Elise J, Simons, Jennifer K, Burzawa, Barbara A, Goff, Paul, Speiser, Elizabeth M, Swisher, Barbara M, Norquist, Rosa Ana, Risques
Publikováno v:
Cancer Res Commun
Current screening methods for ovarian cancer (OC) have failed to demonstrate a significant reduction in mortality. Uterine lavage combined with TP53 ultra-deep sequencing for the detection of disseminated OC cells has emerged as a promising tool, but
Autor:
Rosa Ana Risques, Barbara M. Norquist, Elizabeth M. Swisher, Paul Speiser, Barbara A. Goff, Jennifer K. Burzawa, Elise J. Simons, Kemi M. Doll, John B. Liao, Kathryn P. Pennington, Renata R. Urban, Heidi J. Gray, Ronit Katz, Marc R. Radke, Enna Manhardt, Jeanne Fredrickson, Brendan F. Kohrn, Talayeh S. Ghezelayagh
Current screening methods for ovarian cancer have failed to demonstrate a significant reduction in mortality. Uterine lavage combined with TP53 ultradeep sequencing for the detection of disseminated ovarian cancer cells has emerged as a promising too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935b8042855ea29e7c605d33eb84f855
https://doi.org/10.1158/2767-9764.c.6550803
https://doi.org/10.1158/2767-9764.c.6550803
Autor:
Rosa Ana Risques, Barbara M. Norquist, Elizabeth M. Swisher, Paul Speiser, Barbara A. Goff, Jennifer K. Burzawa, Elise J. Simons, Kemi M. Doll, John B. Liao, Kathryn P. Pennington, Renata R. Urban, Heidi J. Gray, Ronit Katz, Marc R. Radke, Enna Manhardt, Jeanne Fredrickson, Brendan F. Kohrn, Talayeh S. Ghezelayagh
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779d5debab4067df26859628fcf93f10
https://doi.org/10.1158/2767-9764.22544940
https://doi.org/10.1158/2767-9764.22544940
Autor:
Rosa Ana Risques, Barbara M. Norquist, Elizabeth M. Swisher, Paul Speiser, Barbara A. Goff, Jennifer K. Burzawa, Elise J. Simons, Kemi M. Doll, John B. Liao, Kathryn P. Pennington, Renata R. Urban, Heidi J. Gray, Ronit Katz, Marc R. Radke, Enna Manhardt, Jeanne Fredrickson, Brendan F. Kohrn, Talayeh S. Ghezelayagh
Table S1. Clinical patient informationTable S2. Duplex Sequencing gene targetsTable S3. Custom probes for hotspotsTable S4. Mutation Frequency and Mutation Burden by patient and geneTable S5. Codons most frequently mutated in ovarian cancersTable S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74307ae151fd8adb045ea362a8686575
https://doi.org/10.1158/2767-9764.22544937
https://doi.org/10.1158/2767-9764.22544937
Autor:
Rosa Ana Risques, Barbara M. Norquist, Elizabeth M. Swisher, Paul Speiser, Barbara A. Goff, Jennifer K. Burzawa, Elise J. Simons, Kemi M. Doll, John B. Liao, Kathryn P. Pennington, Renata R. Urban, Heidi J. Gray, Ronit Katz, Marc R. Radke, Enna Manhardt, Jeanne Fredrickson, Brendan F. Kohrn, Talayeh S. Ghezelayagh
S1. Experimental designS2. Association between the variant allele frequency (VAF) of tumor mutations identified in uterine lavage with stage of the ovarian cancer (A) and preoperative CA-125 level (B)S3. Gene distribution of the largest mutant clones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846abd237654468ab3ecaaf6e86d4136
https://doi.org/10.1158/2767-9764.22544943
https://doi.org/10.1158/2767-9764.22544943
Autor:
Talayeh Ghezelayagh, Jeanne Fredrickson, Jeffrey Krimmel-Morrison, Brendan Kohrn, Marc Radke, Enna Manhardt, Ronit Katz, Barbara Norquist, Elizabeth Swisher, Rosana Risques
Publikováno v:
Gynecologic Oncology. 166:S125
Autor:
Isabel Rodriguez, Christina Smith, Christopher Pennil, Marc Radke, Sarah Bernards, Enna Manhardt, Francesca Menghi, Edison Liu, Eric Konnick, Elizabeth Swisher
Publikováno v:
Gynecologic Oncology. 166:S68
Autor:
Jeffrey D. Krimmel-Morrison, B. Norquist, Jeanne Fredrickson, Brendan F. Kohrn, Enna Manhardt, Rosa Ana Risques, Talayeh Ghezelayagh, Elizabeth M. Swisher, Marc R. Radke
Publikováno v:
Clinical Research (Excluding Clinical Trials).
Objective: The use of Pap tests as a molecular diagnostic for high-grade serous ovarian carcinoma (HGSC) is a promising concept, but studies to detect tumor DNA report limited sensitivity. “Cancer-like” somatic mutations from clonal expansions in