Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Enma V P Espinosa"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87026 (2014)
There is considerable interest in defining new agents or targets for antithrombotic purposes. The 5-HT2A receptor is a G-protein coupled receptor (GPCR) expressed on many cell types, and a known therapeutic target for many disease states. This seroto
Externí odkaz:
https://doaj.org/article/404a2a1bbd4447abbb69de6b7d9b09b5
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 13 (2018)
Background Despite the well‐established role for the thromboxane A2 receptor (TPR) in the development of thrombotic disorders, none of the antagonists developed to date has been approved for clinical use. To this end, we have previously shown that
Externí odkaz:
https://doaj.org/article/a31a68fdfc3d40128a0f28df7567e5e9
Publikováno v:
Biochemistry and Biophysics Reports, Vol 20, Iss , Pp - (2019)
While changes in intracellular calcium levels is a central step in platelet activation and thrombus formation, the contribution and mechanism of receptor-operated calcium entry (ROCE) via transient receptor potential channels (TRPCs) in platelets rem
Externí odkaz:
https://doaj.org/article/63b7cd8332f6459cabd6178d6aa9273f