Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Enkui Hao"'
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129196 (2015)
Resveratrol (trans-3,4,5'-trihydroxystilbene) is an active compound in food, such as red grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human cancer cells. However, the mechanism of resveratrol-induced anti-cancer
Externí odkaz:
https://doaj.org/article/0af6a3c6bb41402fb4fd2de5cc602af0
Autor:
M. Khair ElZarrad, Partha Mukhopadhyay, Nishant Mohan, Enkui Hao, Milos Dokmanovic, Dianne S. Hirsch, Yi Shen, Pal Pacher, Wen Jin Wu
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/64d14883851c4986981fb4ca858d202d
Autor:
M Khair ElZarrad, Partha Mukhopadhyay, Nishant Mohan, Enkui Hao, Milos Dokmanovic, Dianne S Hirsch, Yi Shen, Pal Pacher, Wen Jin Wu
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79543 (2013)
Treatment with trastuzumab, a humanized monoclonal antibody directed against the extracellular domain of Human Epidermal Growth Factor Receptor 2 (HER2), very successfully improves outcomes for women with HER2-positive breast cancer. However, trastuz
Externí odkaz:
https://doaj.org/article/9531fc3391a14b80b1bd4eb5e226a0cf
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69452 (2013)
BACKGROUND/AIMS: Septic cardiomyopathy is a severe condition that remains a challenge for clinical management. This study investigated whether the natural polyphenolic compound resveratrol could be used as a prophylactic treatment to alleviate sepsis
Externí odkaz:
https://doaj.org/article/c9f6b8f4d567427eb7c44def45902600
Publikováno v:
Experimental and Therapeutic Medicine
Increasing evidence suggest that NOD-like receptor protein 3 (NLRP3) inflammasome-mediated pyroptosis may be the underlying pathological mechanism of sepsis-induced cardiomyopathy. DDX3X, an ATP-dependent RNA helicase, plays a vital role in the forma
Publikováno v:
Food and Chemical Toxicology. 120:104-111
Cyanidin, an anthocyanin pigment, demonstrates anti-oxidant and anti-inflammatory properties. Here, we examined the mechanistic role of cyanidin in endotoxin induced myocardial injury in inflammation and oxidative stress. In lipopolysaccharide (LPS)
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Apigenin, a component in daily diets, demonstrates antioxidant and anti-inflammatory properties. Here, we intended to explore the mechanism of apigenin-mediated endotoxin-induced myocardial injury and its role in the interplay among inflammation, oxi
Autor:
Jinfeng Qu, Enkui Hao, Yuanyuan Zhi, Lanyu Li, Yanping Liu, Haiqin Yin, Fangfang Lang, Zhenghui Fang
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 121
Z-Ligustilide is the most potent bioactive component of Angelica sinensis, which is widely used in Chinese traditional medicine. Z-Ligustilide selectively affected ovarian cancer cell survival in a dose dependent manner. Z-Ligustilide induced apoptot
Autor:
Ju Liu, Thaddeus D. Allen, Fang Guo, Liqun Li, Fengyun Dong, Suhua Yan, Ling Guo, Yinglong Hou, Enkui Hao
Publikováno v:
Biochemical and Biophysical Research Communications. 450:447-452
The vasculature of various organs is a targeted by the environmental toxin, cadmium (Cd). However, mechanisms leading to pathological conditions are poorly understood. In the present study, we examined the effect of cadmium chloride (CdCl2) on human
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2016 (2016)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Elderly patients are susceptible to sepsis. LPS induced myocardial injury is a widely used animal model to assess sepsis induced cardiac dysfunction. The age dependent mechanisms behind sepsis susceptibility were not studied. We analyzed age associat