Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Enjie Liu"'
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-48 (2024)
Abstract Alzheimer’s disease (AD) is the most common neurodegenerative disorder, characterized pathologically by extracellular deposition of β-amyloid (Aβ) into senile plaques and intracellular accumulation of hyperphosphorylated tau (pTau) as ne
Externí odkaz:
https://doaj.org/article/7e1c77e3b8ed40e2ae273155ed209e53
Autor:
Zhiqi Zhang, Enjie Liu, Dandan Zhang, Wugan Zhao, Guannan Wang, Yanping Zhang, Yajun Huo, Chongli Zhang, Wencai Li
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-9 (2023)
Abstract Aims To investigate the expression of polo-like kinase 1 protein (PLK1) and its phosphorylation level (p-PLK1) in extranodal NK/T cell lymphoma (NKTCL) and their correlation with clinical characteristics and prognosis. Methods We collected 4
Externí odkaz:
https://doaj.org/article/1e105176418d433cb9f3cb60d7ab5fa1
Autor:
Dongqin Wu, Nana Yu, Yang Gao, Rui Xiong, Luping Liu, Huiyang Lei, Sen Jin, Jiale Liu, Yingzhou Liu, Jiazhao Xie, Enjie Liu, Qiuzhi Zhou, Yanchao Liu, Shihong Li, Linyu Wei, Jingru Lv, Huilin Yu, Wenbo Zeng, Qiang Zhou, Fuqiang Xu, Min-Hua Luo, Yao Zhang, Ying Yang, Jian-Zhi Wang
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-20 (2023)
Abstract Background Abnormal tau accumulation and cholinergic degeneration are hallmark pathologies in the brains of patients with Alzheimer’s disease (AD). However, the sensitivity of cholinergic neurons to AD-like tau accumulation and strategies
Externí odkaz:
https://doaj.org/article/39fe4c579b394e849b92ba74dcf1104c
Publikováno v:
Healthcare Technology Letters, Vol 9, Iss 3, Pp 34-42 (2022)
Abstract In medical domain, risk factors are often used to model disease predictions. In order to make the most use of the predictive models, linking the model with real patient data generates personalized disease progression and predictions. However
Externí odkaz:
https://doaj.org/article/65bdd062e44a44208a1969333e1c01a7
Autor:
Cunguang Lou, Enjie Liu, Tong Cheng, Jun Li, Hongzan Song, Guangwei Fan, Lei Huang, Bin Dong, Xiuling Liu
Publikováno v:
ACS Omega, Vol 7, Iss 7, Pp 5825-5835 (2022)
Externí odkaz:
https://doaj.org/article/f6115624579e4ff69dc1d13aa9f6994e
Autor:
Bin Jia, Peiyi Xia, Junqiang Dong, Wenhao Feng, Wenjia Wang, Enjie Liu, Guozhong Jiang, Yanru Qin
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundSarcomatoid hepatocellular carcinoma (SHC) is a rare epithelial malignancy with high invasiveness and poor prognosis. However, the molecular characteristics and main driver genes for SHC have not been determined. The aim of this study is to
Externí odkaz:
https://doaj.org/article/e4be9c70c4f24d328e83a3036cd20f82
Autor:
Peiyi Xia, Lan Zhang, Pan Li, Enjie Liu, Wencai Li, Jianying Zhang, Hui Li, Xiaoxing Su, Guozhong Jiang
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Complex kinase rearrangement, a mutational process involving one or two chromosomes with clustered rearrangement breakpoints, interferes with the accurate detection of kinase fusions by DNA-based next-generation sequencing (NGS).
Externí odkaz:
https://doaj.org/article/c1cab8260f22456d9bc9620d2b0c3211
Autor:
Qiuzhi Zhou, Shihong Li, Mengzhu Li, Dan Ke, Qun Wang, Ying Yang, Gong-Ping Liu, Xiao-Chuan Wang, Enjie Liu, Jian-Zhi Wang
Publikováno v:
EBioMedicine, Vol 78, Iss , Pp 103970- (2022)
Summary: Background: Glycogen synthase kinase-3β (GSK-3β) is one of the most effective kinases in promoting tau hyperphosphorylation and accumulation in Alzheimer's disease (AD). However, it is not clear how GSK-3β activity is regulated during AD
Externí odkaz:
https://doaj.org/article/0fcca3d785c44d73ac4603d2974662b7
Autor:
Lan zhang, Pan Li, Enjie Liu, Chenju Xing, Di Zhu, Jianying Zhang, Weiwei Wang, Guozhong Jiang
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The aim of this study was to identify prognostic long non-coding RNAs (lncRNAs) and develop a multi-lncRNA signature for suvival prediction in esophageal squamous cell carcinoma (ESCC). Methods The clinical and gene expression dat
Externí odkaz:
https://doaj.org/article/cd68e2bd47c6441d9f01c6541f239380
Autor:
Dongqin Wu, Di Gao, Haitao Yu, Guilin Pi, Rui Xiong, Huiyang Lei, Xin Wang, Enjie Liu, Jinwang Ye, Huilin Yu, Yang Gao, Ting He, Tao Jiang, Fei Sun, Jingfen Su, Guoda Song, Wenju Peng, Ying Yang, Jian‐Zhi Wang
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 6, Pp n/a-n/a (2021)
Abstract Tau accumulation and cholinergic impairment are characteristic pathologies in Alzheimer's disease (AD). However, the causal role of tau accumulation in cholinergic lesion is elusive. Here, we observed an aberrant tau accumulation in the medi
Externí odkaz:
https://doaj.org/article/88ab01d94fe1451495d1b25853e669bc