Zobrazeno 1 - 10
of 952
pro vyhledávání: '"Enhanced Permeability and Retention effect"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background The tumor microenvironment is profoundly heterogeneous particularly when comparing sites of metastases. Establishing the extent of this heterogeneity may provide guidance on how best to design lipid-based drug delivery systems to
Externí odkaz:
https://doaj.org/article/9192e449a6724fde9d21e119bf73a0bd
Autor:
Patel Harsh, Li Jiaxin, Bo Letao, Mehta Riddhi, Ashby Charles R., Wang Shanzhi, Cai Wei, Chen Zhe-Sheng
Publikováno v:
Medical Review, Vol 4, Iss 1, Pp 5-30 (2024)
Cancer nanomedicine is defined as the application of nanotechnology and nanomaterials for the formulation of cancer therapeutics that can overcome the impediments and restrictions of traditional chemotherapeutics. Multidrug resistance (MDR) in cancer
Externí odkaz:
https://doaj.org/article/29ee7c314ace4ead9811967cc3676da5
Autor:
Huei-Jen Chen, Yi-An Cheng, Yu-Tung Chen, Chia-Ching Li, Bo-Cheng Huang, Shih-Ting Hong, I.-Ju Chen, Kai-Wen Ho, Chiao-Yun Chen, Fang-Ming Chen, Jaw-Yuan Wang, Steve R. Roffler, Tian-Lu Cheng, Tung-Ho Wu
Publikováno v:
Cancer Nanotechnology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background PEGylated nanoparticles (PEG-NPs) are not effective for hematologic malignancies as they lack the enhanced permeability and retention effect (EPR effect). Tumor-targeted PEG-NPs can systemically track lymphoma and actively interna
Externí odkaz:
https://doaj.org/article/d7e948b59260455786e1f5ea63ad1238
Autor:
Jinren Liu, Changzhi Guo, Chunxiang Li, Qiushi Jia, Zhengrong Xie, Ziyue Wang, Hongda Tian, Zhongyuan Li, Liguo Hao
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
The nano drug delivery system MnO2/CDDP@PDA-Cy5.5 was synthesized in this study to increase the efficacy of Cisplatin (CDDP) on thyroid cancer and alleviate the damage to normal tissue, with the aim of enhancing the anti-cancer efficacy, increasing t
Externí odkaz:
https://doaj.org/article/c00affcaa0ea492088caf1221c3142ad
Akademický článek
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Autor:
Jozsef Garai, Pal Kertai
Publikováno v:
SciMedicine Journal, Vol 4, Iss 1, Pp 39-45 (2022)
If a liquid contains suspended solids and flows out of a perforated pipe, the suspended particles of the right size can accumulate and eventually clog the openings. It is suggested that this physical process could be employed to effectively block the
Externí odkaz:
https://doaj.org/article/379d64b1b5794648a94fdd44815a7126
Akademický článek
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Autor:
Toshihiko Tashima
Publikováno v:
Antibodies, Vol 11, Iss 4, p 78 (2022)
Innumerable people worldwide die of cancer every year, although pharmaceutical therapy has actualized many benefits in human health. For background, anti-cancer drug development is difficult due to the multifactorial pathogenesis and complicated path
Externí odkaz:
https://doaj.org/article/b5784f550f27466381d332218fa776aa
Autor:
Prashant Dogra, Joseph D. Butner, Javier Ruiz Ramírez, Yao-li Chuang, Achraf Noureddine, C. Jeffrey Brinker, Vittorio Cristini, Zhihui Wang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 518-531 (2020)
Towards clinical translation of cancer nanomedicine, it is important to systematically investigate the various parameters related to nanoparticle (NP) physicochemical properties, tumor characteristics, and inter-individual variability that affect the
Externí odkaz:
https://doaj.org/article/ee18e8682d7a431a8c6d3577cba2902b
Akademický článek
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