Zobrazeno 1 - 10
of 1 697
pro vyhledávání: '"Engwerda A"'
Autor:
Reena Mukhiya, Wim A. Fleischmann, Jessica R. Loughland, Jo-Anne Chan, Fabian de Labastida Rivera, Dean Andrew, James G. Beeson, James S. McCarthy, Bridget E. Barber, J. Alejandro Lopez, Christian Engwerda, Richard Thomson-Luque, Michelle J. Boyle
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105419- (2024)
Summary: Background: Human immune responses to infection and vaccination are heterogenous, driven by multiple factors including genetics, environmental exposures and personal infection histories. For malaria caused by Plasmodium falciparum parasites,
Externí odkaz:
https://doaj.org/article/61b334fc1a284054a6f4ac3e995a4b50
Autor:
Mukhiya, Reena, Fleischmann, Wim A., Loughland, Jessica R., Chan, Jo-Anne, de Labastida Rivera, Fabian, Andrew, Dean, Beeson, James G., McCarthy, James S., Barber, Bridget E., Lopez, J. Alejandro, Engwerda, Christian, Thomson-Luque, Richard, Boyle, Michelle J.
Publikováno v:
In eBioMedicine November 2024 109
Publikováno v:
In Chem 12 September 2024 10(9):2861-2871
Autor:
Jinrui Na, Christian Engwerda
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Visceral leishmaniasis is a potentially devastating neglected tropical disease caused by the protozoan parasites Leishmania donovani and L. infantum (chagasi). These parasites reside in tissue macrophages and survive by deploying a number of mechanis
Externí odkaz:
https://doaj.org/article/423e65563cd349ec83c9c2965d2c6cff
Autor:
Gulafsha Kausar, Shashi Bhushan Chauhan, Ritirupa Roy, Vimal Verma, Sundaram Pandey, Aziza Niyaz, Jaya Chakravarty, Christian R Engwerda, Susanne Nylen, Rajiv Kumar, Mary E Wilson, Shyam Sundar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 4, p e0012112 (2024)
Visceral leishmaniasis (VL) is a potentially fatal parasitic infection caused by Leishmania donovani in India. L. donovani is an obligate intracellular protozoan residing mostly in macrophages of the reticuloendothelial system throughout chronic infe
Externí odkaz:
https://doaj.org/article/d9e1f83da88a47e6a7c41976c640bee6
Autor:
Nicholas L. Dooley, Tinashe G. Chabikwa, Zuleima Pava, Jessica R. Loughland, Julianne Hamelink, Kiana Berry, Dean Andrew, Megan S. F. Soon, Arya SheelaNair, Kim A. Piera, Timothy William, Bridget E. Barber, Matthew J. Grigg, Christian R. Engwerda, J. Alejandro Lopez, Nicholas M. Anstey, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the development of effective anti-parasitic immunity. Understanding malaria induced tolero
Externí odkaz:
https://doaj.org/article/d4f0ae647bca412fa846c8d4ab492791
Autor:
Shashi Kumar, Shashi Bhushan Chauhan, Shreya Upadhyay, Siddharth Sankar Singh, Vimal Verma, Rajiv Kumar, Christian Engwerda, Susanne Nylén, Shyam Sundar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011960 (2024)
BackgroundCD4+ T cells play a central role in control of L. donovani infection, through IFN-γ production required for activation of macrophages and killing of intracellular parasites. Impaired control of parasites can in part be explained by hampere
Externí odkaz:
https://doaj.org/article/cf7752bbf80e43839e3df17a8abbc225
Autor:
Yulin Wang, Fabian De Labastida Rivera, Chelsea L. Edwards, Teija C.M. Frame, Jessica A. Engel, Luzia Bukali, Jinrui Na, Susanna S. Ng, Dillon Corvino, Marcela Montes de Oca, Patrick T. Bunn, Megan S.F. Soon, Dean Andrew, Jessica R. Loughland, Jia Zhang, Fiona H. Amante, Bridget E. Barber, James S. McCarthy, J. Alejandro Lopez, Michelle J. Boyle, Christian R. Engwerda
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
The development of highly effective malaria vaccines and improvement of drug-treatment protocols to boost antiparasitic immunity are critical for malaria elimination. However, the rapid establishment of parasite-specific immune regulatory networks fo
Externí odkaz:
https://doaj.org/article/3c2a3ba4c5594fffbb78ac8fa7298d0d
Autor:
Eleana Rraku, Wilhelmina S. Kerstjens-Frederikse, Morris A. Swertz, Trijnie Dijkhuizen, Conny M. A. van Ravenswaaij-Arts, Aafke Engwerda
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Terminal 6p deletions are rare, and information on their clinical consequences is scarce, which impedes optimal management and follow-up by clinicians. The parent-driven Chromosome 6 Project collaborates with families of affected
Externí odkaz:
https://doaj.org/article/9c3d5644b96e48dc9ed60be05d88350d
Autor:
Aafke Engwerda, Wilhelmina S. Kerstjens-Frederikse, Nicole Corsten-Janssen, Trijnie Dijkhuizen, Conny M. A. van Ravenswaaij-Arts
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Terminal 6q deletions are rare, and the number of well-defined published cases is limited. Since parents of children with these aberrations often search the internet and unite via international social media platforms, these dedica
Externí odkaz:
https://doaj.org/article/dfee0e5131eb49a09ec2b063804165ed