Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Enguo Ju"'
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 611-626 (2024)
The specific induction of hepatic differentiation presents a significant challenge in developing alternative liver cell sources and viable strategies for clinical therapy of acute liver failure (ALF). The past decade has witnessed the blossom of micr
Externí odkaz:
https://doaj.org/article/1bee14913dbf4b5ea0e41ff8de8bda5f
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 50-60 (2023)
As the most abundant liver-specific microRNA, microRNA-122 (miR122) played a crucial role in the differentiation of stem cells into hepatocytes. However, highly efficient miR122 delivery still confronts challenges including poor cellular uptake and e
Externí odkaz:
https://doaj.org/article/9e76809b783e420ab3a40c44d22700c6
Autor:
Jungang Lan, Yeqing Wang, Shusheng Yue, Duo Xu, Yinan Li, Xiangyu Peng, Jiao Hu, Enguo Ju, Shanping He, Tingting Li
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011581 (2023)
Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic virus consisting of both latent and lytic life cycles. Primary effusion lymphoma (PEL) is an aggressive B-cell lineage lymphoma, dominantly latently infected by KSHV. The latent infection
Externí odkaz:
https://doaj.org/article/180788e31a9a4fd288632922eca71f26
Autor:
Youqiang Fang, Xing Luo, Yanteng Xu, Zheng Liu, Rachel L. Mintz, Haiyang Yu, Xuan Yu, Kai Li, Enguo Ju, Haixia Wang, Zhaohui Tang, Yu Tao, Mingqiang Li
Publikováno v:
Advanced Science, Vol 10, Iss 22, Pp n/a-n/a (2023)
Abstract As a currently common strategy to treat cancer, surgical resection may cause tumor recurrence and metastasis due to residual postoperative tumors. Herein, an implantable sandwich‐structured dual‐drug depot is developed to trigger a self
Externí odkaz:
https://doaj.org/article/08ab8f413f574c14b3a28ee87ce65cc4
Autor:
Wentao Dang, Wei-Chih Chen, Enguo Ju, Yanteng Xu, Kai Li, Haixia Wang, Kun Wang, Shixian Lv, Dan Shao, Yu Tao, Mingqiang Li
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Surgical resection to achieve tumor-free margins represents a difficult clinical scenario for patients with hepatocellular carcinoma. While post-surgical treatments such as chemotherapy and radiotherapy can decrease the risk of cancer recurr
Externí odkaz:
https://doaj.org/article/7eaebe87ec08427a93d696f11d984760
Autor:
Tingting Li, Xian Wang, Enguo Ju, Suzane Ramos da Silva, Luping Chen, Xinquan Zhang, Shan Wei, Shou-Jiang Gao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
CASTOR1 is an arginine sensor that inhibits mTORC1 activation, for which this pathway is frequently dysregulated in cancers. Here the authors show that AKT and E3 ubiquitin ligase RNF167 mediate CASTOR1 phosphorylation and degradation to activate mTO
Externí odkaz:
https://doaj.org/article/5d106505773e4634b6f3104272c163b7
Autor:
Huimin Kong, Enguo Ju, Ke Yi, Weiguo Xu, Yeh‐Hsing Lao, Du Cheng, Qi Zhang, Yu Tao, Mingqiang Li, Jianxun Ding
Publikováno v:
Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract Liver disease, particularly viral hepatitis and hepatocellular carcinoma (HCC), is a global healthcare burden and leads to more than 2 million deaths per year worldwide. Despite some success in diagnosis and vaccine development, there are st
Externí odkaz:
https://doaj.org/article/37bcfc3ff94b40c28078c55a4e3d79be
Autor:
Shan Wei, Songjian Lu, Lifan Liang, Xian Wang, Wan Li, Tingting Li, Luping Chen, Enguo Ju, Xinquan Zhang, Zhao Lai, Yufei Huang, Xinghua Lu, Shou-Jiang Gao
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT Infection by Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally associated with numerous cancers. The mechanism of KSHV-induced oncogenesis remains unclear. By performing a CRISPR-Cas9 screening in a model of KSHV-induced cellular
Externí odkaz:
https://doaj.org/article/e354e8b1974b46c1aac37c45c689486c
Autor:
Zhenzhen Wang, Yan Zhang, Enguo Ju, Zhen Liu, Fangfang Cao, Zhaowei Chen, Jinsong Ren, Xiaogang Qu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Hypoxic tumors are resistant to dynamic therapy, limiting potential treatment options. Here, the authors describe a nanoflower where oxidase mimicking PtCo nanoparticles are decorated with catalase mimicking MnO2 to reverse tumor hypoxia and generate
Externí odkaz:
https://doaj.org/article/288800d421ff43d08494bee673ac3efb
Autor:
Peng Shi, Enguo Ju, Zhengqing Yan, Nan Gao, Jiasi Wang, Jianwen Hou, Yan Zhang, Jinsong Ren, Xiaogang Qu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Reversible manipulation of cell-cell interactions has potential applications in basic research and cell-based therapy. Here the authors control cell-cell adhesion in vitrowith light, by modifying the surface sugars of cells to display β-cyclodextrin
Externí odkaz:
https://doaj.org/article/114d215b6eaf46bbb46168dbe2cb2ff1