Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments.

Autor: Moreno-Vicente J; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Willoughby JE; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Taylor MC; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Booth SG; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., English VL; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Williams EL; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Penfold CA; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Mockridge CI; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Inzhelevskaya T; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Kim J; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Chan HTC; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Cragg MS; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Gray JC; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK., Beers SA; Antibody and Vaccine Group, Centre for Cancer Immunology, Cancer Sciences, University of Southampton, Southampton, UK s.a.beers@soton.ac.uk.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2022 Jan; Vol. 10 (1).

Deficiency of angiotensinogen in hepatocytes markedly decreases blood pressure in lean and obese male mice.

Autor: Yiannikouris F; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Wang Y; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Shoemaker R; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Larian N; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Thompson J; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., English VL; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Charnigo R; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Su W; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Gong M; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington., Cassis LA; From the Departments of Pharmacology and Nutritional Sciences (F.Y., Y.W., R.S., N.L., V.L.E., L.A.C.), Statistics (R.C.), and Physiology (W.S., M.G.) and Division of Endocrinology and Molecular Medicine (J.T.), University of Kentucky, Lexington. lcassis@uky.edu.

Publikováno v: Hypertension (Dallas, Tex. : 1979) [Hypertension] 2015 Oct; Vol. 66 (4), pp. 836-42. Date of Electronic Publication: 2015 Aug 24.

Angiotensin II Stimulates Sympathetic Neurotransmission to Adipose Tissue.

Autor: King VL; Division of Cardiology, University of Kentucky, Lexington, KY 40536., English VL, Bharadwaj K, Cassis LA

Publikováno v: Physiological reports [Physiol Rep] 2013 Aug; Vol. 1 (2).

ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet.

Autor: Gupte M; Graduate Center for Nutritional Sciences, Rm. 521b, Wethington Bldg., 900 S. Limestone, College of Medicine, Univ. of Kentucky, Lexington, KY 40536-0200, USA., Boustany-Kari CM, Bharadwaj K, Police S, Thatcher S, Gong MC, English VL, Cassis LA

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2008 Sep; Vol. 295 (3), pp. R781-8. Date of Electronic Publication: 2008 Jul 23.