Standardization of zebrafish drug testing parameters for muscle diseases.

Autor: Karuppasamy M; Division of Neurology, Department of Pediatrics, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA., English KG; Division of Neurology, Department of Pediatrics, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA., Henry CA; Graduate School of Biomedical Science and Engineering, University of Maine, Orono, ME 04469, USA.; School of Biology and Ecology, University of Maine, Orono, ME 04469, USA., Manzini MC; Child Health Institute of New Jersey and Department of Neuroscience and Cell Biology, Rutgers, Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA., Parant JM; Department of Pharmacology and Toxicology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA., Wright MA; Department of Pediatrics, Section of Child Neurology, University of Colorado at Anschutz Medical Campus, Aurora, CO 80045, USA., Ruparelia AA; Department of Anatomy and Physiology, School of Biomedical Sciences, Faculty of Medicine Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria 3010, Australia.; Centre for Muscle Research, Department of Anatomy and Physiology, University of Melbourne, Melbourne, Victoria 3010, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia., Currie PD; Centre for Muscle Research, Department of Anatomy and Physiology, University of Melbourne, Melbourne, Victoria 3010, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia.; EMBL Australia, Victorian Node, Monash University, Clayton, Victoria 3800, Australia., Gupta VA; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Dowling JJ; Division of Neurology, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.; Department of Paediatrics, University of Toronto, Toronto, Ontario M5G 1X8, Canada.; Program for Genetics and Genome Biology, The Hospital for Sick Children, Toronto, Ontario M5G 0A4, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada., Maves L; Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98195, USA., Alexander MS; Division of Neurology, Department of Pediatrics, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA.; UAB Center for Exercise Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Civitan International Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; UAB Center for Neurodegeneration and Experimental Therapeutics (CNET), Birmingham, AL 35294, USA.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2024 Jan 01; Vol. 17 (1). Date of Electronic Publication: 2024 Jan 18.

Next-Generation SINE Compound KPT-8602 Ameliorates Dystrophic Pathology in Zebrafish and Mouse Models of DMD.

Autor: English KG; Department of Pediatrics, Division of Neurology at Children's of Alabama the University of Alabama at Birmingham, Birmingham, AL 35233, USA., Reid AL; Department of Pediatrics, Division of Neurology at Children's of Alabama the University of Alabama at Birmingham, Birmingham, AL 35233, USA., Samani A; Department of Pediatrics, Division of Neurology at Children's of Alabama the University of Alabama at Birmingham, Birmingham, AL 35233, USA., Coulis GJF; Department of Physiology and Biophysics, University of California-Irvine, Irvine, CA 92697, USA.; Institute for Immunology, University of California-Irvine, Irvine, CA 92967, USA., Villalta SA; Department of Physiology and Biophysics, University of California-Irvine, Irvine, CA 92697, USA.; Institute for Immunology, University of California-Irvine, Irvine, CA 92967, USA., Walker CJ; Karyopharm Therapeutics, Newton, MA 02459, USA., Tamir S; Karyopharm Therapeutics, Newton, MA 02459, USA., Alexander MS; Department of Pediatrics, Division of Neurology at Children's of Alabama the University of Alabama at Birmingham, Birmingham, AL 35233, USA.; UAB Center for Exercise Medicine (UCEM), Birmingham, AL 35205, USA.; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL 35233, USA.; UAB Civitan International Research Center (CIRC), Birmingham, AL 35233, USA.; UAB Center for Neurodegeneration and Experimental Therapeutics (CNET), Birmingham, AL 35294, USA.

Publikováno v: Biomedicines [Biomedicines] 2022 Sep 26; Vol. 10 (10). Date of Electronic Publication: 2022 Sep 26.

miR-486 is essential for muscle function and suppresses a dystrophic transcriptome.

Autor: Samani A; Department of Pediatrics, Division of Neurology at Children's of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA., Hightower RM; Department of Pediatrics, Division of Neurology at Children's of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA.; University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA., Reid AL; Department of Pediatrics, Division of Neurology at Children's of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA., English KG; Department of Pediatrics, Division of Neurology at Children's of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA., Lopez MA; Department of Pediatrics, Division of Neurology at Children's of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA.; University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA., Doyle JS; Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA., Conklin MJ; Department of Orthopedic Surgery, at the University of Alabama at Birmingham, Birmingham, AL, USA., Schneider DA; Department of Biochemistry and Molecular Genetics at the University of Alabama at Birmingham, Birmingham, AL, USA., Bamman MM; University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA., Widrick JJ; Division of Genetics and Genomics at Boston Children's Hospital, Boston, MA, USA., Crossman DK; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA., Xie M; Division of Cardiovascular Disease, Department of Medicine, University of Alabama at Birmingham, School of Medicine, Birmingham, AL, USA., Jee D; Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA.; Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Lai EC; Developmental Biology Program, Sloan Kettering Institute, New York, NY, USA.; Weill Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Alexander MS; Department of Pediatrics, Division of Neurology at Children's of Alabama and the University of Alabama at Birmingham, Birmingham, AL, USA matthewalexander@uabmc.edu.; University of Alabama at Birmingham Center for Exercise Medicine (UCEM), Birmingham, AL, USA.; Department of Genetics, University of Alabama at Birmingham, Birmingham, AL, USA.; UAB Civitan International Research Center (CIRC), at the University of Alabama at Birmingham, Birmingham, AL, USA.

Publikováno v: Life science alliance [Life Sci Alliance] 2022 May 05; Vol. 5 (9). Date of Electronic Publication: 2022 May 05 (Print Publication: 2022).