Zobrazeno 1 - 10 of 133 pro vyhledávání: '"England RM"'
1
Akademický článek
Exploring the Conformational Landscape of Poly(l-lysine) Dendrimers Using Ion Mobility Mass Spectrometry.
Autor: Benoit F; Michael Barber Centre for Collaborative Mass Spectrometry, Manchester Institute of Biotechnology, Department of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K., Wang X; Michael Barber Centre for Collaborative Mass Spectrometry, Manchester Institute of Biotechnology, Department of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K., Dai J; Michael Barber Centre for Collaborative Mass Spectrometry, Manchester Institute of Biotechnology, Department of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K., Geue N; Michael Barber Centre for Collaborative Mass Spectrometry, Manchester Institute of Biotechnology, Department of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K., England RM; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield SK10 2NA, U.K., Bristow AWT; Chemical Development, Pharmaceutical Technology and Development, Operations, AstraZeneca, Macclesfield SK10 2NA, U.K., Barran PE; Michael Barber Centre for Collaborative Mass Spectrometry, Manchester Institute of Biotechnology, Department of Chemistry, The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.
Publikováno v: Analytical chemistry [Anal Chem] 2024 Jun 11; Vol. 96 (23), pp. 9390-9398. Date of Electronic Publication: 2024 May 29.
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2
Akademický článek
Modular design of cyclic peptide - polymer conjugate nanotubes for delivery and tunable release of anti-cancer drug compounds.
Autor: Hill SK; Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK., England RM; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield, UK., Perrier S; Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK; Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK; Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, VIC 3052, Australia. Electronic address: S.Perrier@warwick.ac.uk.
Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Mar; Vol. 367, pp. 687-696. Date of Electronic Publication: 2024 Feb 09.
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3
Akademický článek
Evolution of nanomedicine formulations for targeted delivery and controlled release.
Autor: Puri S; Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Mazza M; Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK. Electronic address: mariarosa.mazza@astrazeneca.com., Roy G; Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca, Biologics Engineering, Oncology R&D, United States., England RM; Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca, Macclesfield, UK., Zhou L; Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca, Boston, MA, USA., Nourian S; Emerging Innovations Unit, Discovery Sciences, Biopharmaceutical R&D , AstraZeneca, Gaithersburg, MD, USA., Anand Subramony J; Advanced Drug Delivery, BioPharmaceuticals R&D, AstraZeneca, Biologics Engineering, Oncology R&D, United States. Electronic address: anand.subramony@lilly.com.
Publikováno v: Advanced drug delivery reviews [Adv Drug Deliv Rev] 2023 Sep; Vol. 200, pp. 114962. Date of Electronic Publication: 2023 Jun 13.
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4
Akademický článek
Precise and systematic end group chemistry modifications on PAMAM and poly(l-lysine) dendrimers to improve cytosolic delivery of mRNA.
Autor: Joubert F; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield, UK., Munson MJ; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden., Sabirsh A; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden., England RM; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield, UK. Electronic address: Richard.England@astrazeneca.com., Hemmerling M; Medicinal Chemistry, Early Respiratory & Immunology, R&D, AstraZeneca, Gothenburg, Sweden., Alexander C; School of Pharmacy, University of Nottingham, Nottingham, UK., Ashford MB; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield, UK.
Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2023 Apr; Vol. 356, pp. 580-594. Date of Electronic Publication: 2023 Mar 17.
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5
Akademický článek
Method to Investigate the Distribution of Water-Soluble Drug-Delivery Systems in Fresh Frozen Tissues Using Imaging Mass Cytometry.
Autor: Strittmatter N; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., England RM; Advanced Drug Delivery, Pharmaceutical Sciences, R&D BioPharmaceuticals, AstraZeneca, Macclesfield SK10 2NA, U.K., Race AM; Institute of Medical Bioinformatics and Biostatistics, Philipps University of Marburg, Marburg 35037, Germany., Sutton D; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., Moss JI; Bioscience, Discovery, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Maglennon G; Oncology Safety, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., Ling S; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., Wong E; Antibody Discovery and Protein Engineering, R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Rose J; Animal Sciences and Technologies, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., Purvis I; Animal Sciences and Technologies, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., Macdonald R; Animal Sciences and Technologies, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K., Barry ST; Bioscience, Discovery, Oncology R&D, AstraZeneca, Cambridge CB2 0AA, U.K., Ashford MB; Advanced Drug Delivery, Pharmaceutical Sciences, R&D BioPharmaceuticals, AstraZeneca, Macclesfield SK10 2NA, U.K., Goodwin RJA; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, R&D BioPharmaceuticals, AstraZeneca, Cambridge CB2 0AA, U.K.; Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, U.K.
Publikováno v: Analytical chemistry [Anal Chem] 2021 Mar 02; Vol. 93 (8), pp. 3742-3749. Date of Electronic Publication: 2021 Feb 19.
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6
Akademický článek
Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications.
Autor: England RM; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield SK10 2NA, U.K.; Early Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield SK10 4TF, U.K., Moss JI; Early TDE, Oncology R&D, AstraZeneca, Cambridge CB4 0WG, U.K., Gunnarsson A; Discovery Sciences, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg 431 50, Sweden., Parker JS; Early Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield SK10 4TF, U.K., Ashford MB; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield SK10 2NA, U.K.
Publikováno v: Biomacromolecules [Biomacromolecules] 2020 Aug 10; Vol. 21 (8), pp. 3332-3341. Date of Electronic Publication: 2020 Jul 28.
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7
Akademický článek
In vivo fluorescence imaging of nanocarriers in near-infrared window II based on aggregation-caused quenching.
Autor: Zhang, Zichen1 (AUTHOR), Liu, Chang1 (AUTHOR), Lu, Yi1,2,3 (AUTHOR), Zhao, Weili1,2 (AUTHOR), Zhu, Quangang2 (AUTHOR), He, Haisheng1 (AUTHOR) he_haisheng@fudan.edu.cn, Chen, Zhongjian2 (AUTHOR) aajian818@163.com, Wu, Wei1,2,3,4 (AUTHOR) wuwei@shmu.edu.cn
Publikováno v: Journal of Nanobiotechnology. 8/14/2024, Vol. 22 Issue 1, p1-16. 16p.
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8
Akademický článek
Endocytic Profiling of Cancer Cell Models Reveals Critical Factors Influencing LNP-Mediated mRNA Delivery and Protein Expression.
Autor: Sayers EJ; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales., Peel SE; Discovery Biology, Discovery Sciences, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Schantz A; Advanced Drug Delivery, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden., England RM; Early Chemical Development, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca, Macclesfield, UK., Beano M; Pathology, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Bates SM; Pathology, Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Desai AS; Advanced Drug Delivery, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Puri S; Advanced Drug Delivery, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca, Cambridge, UK., Ashford MB; Advanced Drug Delivery, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca, Cambridge, UK. Electronic address: marianne.ashford@astrazeneca.com., Jones AT; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales. Electronic address: jonesat@cardiff.ac.uk.
Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2019 Nov 06; Vol. 27 (11), pp. 1950-1962. Date of Electronic Publication: 2019 Aug 05.
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9
Akademický článek
Evaluating liver uptake and distribution of different poly(2-methyl-2-oxazoline) modified lysine dendrimers following intravenous administration.
Autor: England RM; Early Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield, UK. Richard.England@astrazeneca.com., Moss JI; Bioscience, R&D Oncology, AstraZeneca, Cambridge, UK., Hill KJ; Global Pharmaceutical Development, Pharmaceutical Technology and Development, Operations, AstraZeneca, Macclesfield, UK., Elvevold K; D'Liver AS, P.O. Box 6416, NO-9294 Tromsø, Norway., Smedsrød B; D'Liver AS, P.O. Box 6416, NO-9294 Tromsø, Norway and Vascular Biology Research Group, Department of Medical Biology, University of Tromsø, Tromsø, Norway., Ashford MB; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, Macclesfield, UK.
Publikováno v: Biomaterials science [Biomater Sci] 2019 Aug 01; Vol. 7 (8), pp. 3418-3424. Date of Electronic Publication: 2019 Jul 03.
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10
Akademický článek
Polyacetal-Based Combination Therapy for the Treatment of Prostate Cancer.
Autor: Plyduang T; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkla, 90112, Thailand.; School of Pharmacy, Walailak University, Thasala, Nakhon Si Thammarat, 80161, Thailand., Armiñán A; Polymer Therapeutics Laboratory, Centro de Investigación Príncipe Felipe, Av Eduardo Primo Yúfera 3, 46012, Valencia, Spain., Movellan J; Polymer Therapeutics Laboratory, Centro de Investigación Príncipe Felipe, Av Eduardo Primo Yúfera 3, 46012, Valencia, Spain., England RM; Polymer Therapeutics Laboratory, Centro de Investigación Príncipe Felipe, Av Eduardo Primo Yúfera 3, 46012, Valencia, Spain., Wiwattanapatapee R; Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkla, 90112, Thailand., Vicent MJ; Polymer Therapeutics Laboratory, Centro de Investigación Príncipe Felipe, Av Eduardo Primo Yúfera 3, 46012, Valencia, Spain.
Publikováno v: Macromolecular rapid communications [Macromol Rapid Commun] 2018 Oct; Vol. 39 (19), pp. e1800265. Date of Electronic Publication: 2018 Jul 30.
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