Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Engin Demirdizen"'
Autor:
Jong-Whi Park, Omer Kilic, Minh Deo, Kevin Jimenez-Cowell, Engin Demirdizen, Hyunggee Kim, Şevin Turcan
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Capicua (CIC) is an important downstream molecule of RTK/RAS/MAPK pathway. The regulatory mechanism of CIC underlying tumorigenesis in oligodendroglioma, where CIC is frequently mutated, has yet to be fully elucidated. Using patient-derived
Externí odkaz:
https://doaj.org/article/fa0f02994ce642d6bf67a50fef6ccde1
Autor:
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Publikováno v:
Neuro-oncology.
Background IDH mutant gliomas are grouped into astrocytomas or oligodendrogliomas depending on the codeletion of chromosome arms 1p and 19q. Although the genomic alterations of IDH mutant gliomas have been well described, transcriptional changes uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5705037f5243af52e2ed391c93f917ed
https://pubmed.ncbi.nlm.nih.gov/36215168
https://pubmed.ncbi.nlm.nih.gov/36215168
Autor:
Anna Schönrock, Elisa Heinzelmann, Bianca Steffl, Engin Demirdizen, Ashwin Narayanan, Damir Krunic, Marion Bähr, Jong-Whi Park, Claudia Schmidt, Koray Özduman, M Necmettin Pamir, Wolfgang Wick, Felix Bestvater, Dieter Weichenhan, Christoph Plass, Julian Taranda, Moritz Mall, Şevin Turcan
Publikováno v:
Neuro Oncol
Background Glioblastoma (GBM) is an aggressive tumor that frequently exhibits gain of chromosome 7, loss of chromosome 10, and aberrantly activated receptor tyrosine kinase signaling pathways. Previously, we identified Mesenchyme Homeobox 2 (MEOX2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf951fbefb8d31316b27733d0feb0dc
https://doi.org/10.1093/neuonc/noac110
https://doi.org/10.1093/neuonc/noac110
Autor:
Julianna Patricia Varga, Sevin Turcan, Engin Demirdizen, Felix Bestvater, Gabriele Schmidt, Julian Taranda, Bianca Steffl, Damir Krunic, Xueyuan Sun, Ruslan Al-Ali, Claudia Schmidt, Manuela Brom, Ashwin Narayanan
Oligodendrogliomas are a subtype of isocitrate dehydrogenase (IDH) mutant gliomas defined by the co-deletion of chromosome arms 1p and 19q. Although the somatic genomic alterations of oligodendrogliomas have been well described, transcriptional chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f5a521542fc178d9e679c58a17bb409
https://doi.org/10.1101/2021.11.05.467405
https://doi.org/10.1101/2021.11.05.467405
Autor:
Charbel Abi Khalil, Robert E. Akins, T. Alenghat, Emily G Allen, N. Altorok, Lucia Altucci, Aneta Balcerczyk, Isabel Barragán, Marta Biesiekierska, Vinayak S. Biradar, Sarah J. Blossom, Patricia Chaves, D. Chen, Hong Chen, Shijia Alexia Chen, Baoli Cheng, P. Chun, Oskar Ciesielski, Maricarmen Colon-Diaz, O.H. Cox, Angela Cozma, Xiaolong Cui, F.J. Dekker, Carmela Dell’Aversana, Engin Demirdizen, Jiali Deng, Deepti D. Deobagkar, Mona Dvir-Ginzberg, Devon Ehnes, J.C. Eissenberg, Perla M. Elosegui, Adriana Fodor, A. Ganesan, Cristina Giorgio, Mengying Guo, J.G. Hall, S. Hashimoto-Hill, Mustapha Umar Imam, Maznah Ismail, Alexander J. Jaramillo, M.P. Jennings, Peng Jin, A.C. Johnson, B. Kahaleh, D.R. Kelly, Alexander Koliada, Narasaiah Kolliputi, Ashok Kumar, R.S. Lee, Anait S. Levenson, Shiri Levy, C.O. Ligon, Maria Liguori, Ji Liu, T. Louwies, Qianjin Lu, Shuaihantian Luo, Oleh Lushchak, B. Greenwood-Van Meerveld, Rachel L. Miller, V. Nagaraja, Shyamala C. Navada, Nicoletta Nuzziello, Jessica Oh, Elisa Oltra, Juan Luis Onieva, Der Jiun Ooi, Luciano Pirola, S. Proschinger, Shriram N. Rajpathak, Karyn G. Robinson, Gabriela Roman, Hannele Ruohola-Baker, Adriana Rusu, Kamaldeen Olalekan Sanusi, A. Schenk, K.L. Seib, Giulia Sgueglia, Liqi Shu, J. Singh, Adela Sitar-Tăut, Edwin Y. Soto, Ramona Suharoschi, J. Tajbakhsh, Francesco Paolo Tambaro, Julian Taranda, Akshaya Thoutam, Trygve O. Tollefsbol, P. Trojer, Sevin Turcan, Yaaqub Abiodun Uthman, Alexander Vaiserman, Romana Vulturar, Huan Wang, H. Wapenaar, R. Weksberg, Junjie Xiao, Guanying Bianca Xu, Chang Zeng, Wei Zhang, Zhou Zhang, P. Zimmer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38d56f387ad3c9d95147a038c548b740
https://doi.org/10.1016/b978-0-12-823928-5.09989-8
https://doi.org/10.1016/b978-0-12-823928-5.09989-8
Publikováno v:
Medical Epigenetics ISBN: 9780128239285
The majority of solid tumors harbor disrupted epigenomes that contribute to malignancy. Over the past decade, there has been a substantial increase in our understanding of the epigenetic mechanisms underlying normal and disease states. Profiling of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2cda03b6acc97b364e7919148c630c4
https://doi.org/10.1016/b978-0-12-823928-5.00013-x
https://doi.org/10.1016/b978-0-12-823928-5.00013-x
Autor:
Sevin Turcan, Ashwin Narayanan, Engin Demirdizen, Matthias Schlesner, Enrique Blanco-Carmona, Christel Herold-Mende, Xueyuan Sun
Publikováno v:
Journal of Visualized Experiments.
Adult diffuse gliomas exhibit inter- and intra-tumor heterogeneity. Until recently, the majority of large-scale molecular profiling efforts have focused on bulk approaches that led to the molecular classification of brain tumors. Over the last five y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c2c711d7de4054d56d55078d10bf0b
https://doi.org/10.3791/61542
https://doi.org/10.3791/61542
Autor:
Matthias Spiller-Becker, Debora Bade, Bernd Hessling, Andrea Bergner, Arion Förtsch, Samuel Corless, Sylvia Erhardt, Engin Demirdizen, Alexander Wilhelm
Publikováno v:
Nucleic Acids Research
Centromere function requires the presence of the histone H3 variant CENP-A in most eukaryotes. The precise localization and protein amount of CENP-A are crucial for correct chromosome segregation, and misregulation can lead to aneuploidy. To characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2900ed464322e42c30cb1d2f5b2b82e
https://doi.org/10.1093/nar/gkz962
https://doi.org/10.1093/nar/gkz962
Autor:
'Engin Demirdizen
Publikováno v:
Matthias Spiller-Becker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::d4bdf222c428bbbc0fe2ab903729964c