Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Engin Bojnik"'
Autor:
Enrica Rampazzo, Engin Bojnik, Livio Trentin, Laura Bonaldi, Paola Del Bianco, Federica Frezzato, Andrea Visentin, Monica Facco, Gianpietro Semenzato, Anita De Rossi
Publikováno v:
Haematologica, Vol 102, Iss 7 (2017)
Externí odkaz:
https://doaj.org/article/b1774ab19fa5408092d8bc4d238a2342
Autor:
Francisco de Paula Careta, Stefania Gobessi, Rodrigo Alexandre Panepucci, Engin Bojnik, Fabio Morato de Oliveira, Daniel Mazza Matos, Roberto P. Falcão, Luca Laurenti, Marco A. Zago, Dimitar G. Efremov
Publikováno v:
Haematologica, Vol 97, Iss 8 (2012)
Background The malignant B cells in chronic lymphocytic leukemia receive signals from the bone marrow and lymph node microenvironments which regulate their survival and proliferation. Characterization of these signals and the pathways that propagate
Externí odkaz:
https://doaj.org/article/56215780661748ffadcbcb2107e099b5
Autor:
Paola Del Bianco, Engin Bojnik, Anita De Rossi, Enrica Rampazzo, Monica Facco, Andrea Visentin, Gianpietro Semenzato, Federica Frezzato, Livio Trentin, Laura Bonaldi
Publikováno v:
Haematologica. 102:e253-e256
Chronic lymphocytic leukemia (CLL), the most prevalent form of leukemia in adults in the western world, has a highly heterogeneous clinical course, and is characterized by genomic instability which gives rise to several chromosomal alterations detect
Autor:
Patrycja Kleczkowska, Agnieszka Kowalczyk, Magdalena Bujalska-Zadrożny, Sándor Benyhe, Engin Bojnik, Andrzej W. Lipkowski, Barbara Nowicka, Karolina Pawlik, Piotr Kosson, Emmanuel Hermans, Anna Lesniak, Aleksandra Misicka
Publikováno v:
Brain Research. 1648:172-180
Hybrid compounds are suggested to be a more effective remedy for treatment of various diseases than combination therapy, since the attenuation or total disappearance of side effects, typically induced by a single moiety, can be observed. This is of g
Autor:
Claudio Martines, Malgorzata Bobrowicz, Sven Turkalj, Beata Pyrzynska, Joanna Stachura, Binu K. Sasi, Engin Bojnik, Francesco Bertoni, Dimitar G. Efremov, Magdalena Winiarska, Richard Rosenquist, Elena Xerxa, Hilal Kalkan, Larry Mansouri, Valdemar Priebe, Fabiola Porro, Rosa Fazio, Abdessamad Zerrouqi
Publikováno v:
Leukemia. 33(10)
The BCL-2 inhibitor venetoclax has only limited activity in DLBCL despite frequent BCL-2 overexpression. Since constitutive activation of the B cell receptor (BCR) pathway has been reported in both ABC and GCB DLBCL, we investigated whether targeting
Autor:
Enrica, Rampazzo, Engin, Bojnik, Livio, Trentin, Laura, Bonaldi, Paola, Del Bianco, Federica, Frezzato, Andrea, Visentin, Monica, Facco, Gianpietro, Semenzato, Anita, De Rossi
Publikováno v:
Haematologica. 102(7)
Autor:
Fabiola Porro, Engin Bojnik, Francesco Bertoni, Binu K. Sasi, Beata Pyrzynska, Abdessamad Zerrouqi, Richard Rosenquist, Dimitar G. Efremov, Magdalena Winiarska, Malgorzata Bobrowicz, Sven Turkalj, Valdemar Priebe, Hilal Kalkan, Larry Mansouri
Publikováno v:
Blood. 132:2860-2860
Functional and transcriptional profiling studies have identified a subset of diffuse large B cell lymphoma (DLBCL) tumors that rely on B cell receptor (BCR) signals for proliferation and survival. These BCR-dependent tumors have been identified among
Autor:
Grazia Luisi, Adriano Mollica, Azzurra Stefanucci, Engin Bojnik, Sándor Benyhe, Roberto Costante, Francesco Pinnen, Anna Borsodi, Stefano Pieretti
Publikováno v:
European Journal of Medicinal Chemistry. 68:167-177
Endomorphin-2 [Tyr-Pro-Phe-Phe-NH2] and DAMGO [Tyr-D-Ala-Gly-(N-Me)Phe-Gly-ol] are natural (EM2) and synthetic (DAMGO) opioid peptides both selective for μ opioid receptor with high analgesic activity. In this work we report synthesis, in vitro and
Autor:
Engin Bojnik, Sándor Benyhe, Steven Ballet, Dirk Tourwé, Piotr Kosson, Lipkowski Andrzej W, Isabelle Van den Eynde, Patrycja Kleczkowska, Anna Leśniak
Publikováno v:
Pharmacological Reports. 65:836-846
Background Recently, we presented a novel compound (PK20, Dmt-D-Lys-Phe-Phe-Lys-Lys-Pro-Phe-Tle-Leu-OH) that targets single entity opioid and neurotensin pharmacophores. This endomorphin-2-like opioid peptide was introduced as a highly active analges
Autor:
Guliz Armagan, Lutfiye Kanit, Anna Borsodi, Ayfer Yalcin, Sándor Benyhe, Ezgi Turunc Bayrakdar, Engin Bojnik
Publikováno v:
Epilepsy Research. 105:13-19
The opioid/nociceptin receptors are involved in many neurological disorders such as Alzheimer's disease, Parkinson's disease and epilepsy. Kainic acid (KA) is an analog of the excitatory amino acid transmitter glutamate and the systemic administratio