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Accumulating evidence suggests that posttranscriptional control of gene expression, including RNA splicing, transport, modification, translation, and degradation, primarily relies on RNA binding proteins (RBPs). However, the functions of many RBPs re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3a9eeb20d0c21ffd0248ef783cec09
https://doi.org/10.1101/2022.12.16.520836
https://doi.org/10.1101/2022.12.16.520836
Publikováno v:
Circulation Research. 131
Translation of upstream open reading frames (uORFs) typically abrogates translation for the main ORF (mORF) and regulates protein expression. uORFs are present in nearly 50% of messenger RNA (mRNA) transcripts, but their impact and regulation on biol