Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eng K, Gan"'
Autor:
Tim G St Pierre, Michael J House, Sander J Bangma, Wenjie Pang, Andrew Bathgate, Eng K Gan, Oyekoya T Ayonrinde, Prithi S Bhathal, Andrew Clouston, John K Olynyk, Leon A Adams
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160789 (2016)
Validation of non-invasive methods of liver fat quantification requires a reference standard. However, using standard histopathology assessment of liver biopsies is problematical because of poor repeatability. We aimed to assess a stereological metho
Externí odkaz:
https://doaj.org/article/0c7c74ec362440f7af1973d4c9856c78
Autor:
Michael J House, Eng K Gan, Leon A Adams, Oyekoya T Ayonrinde, Sander J Bangma, Prithi S Bhathal, John K Olynyk, Tim G St Pierre
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59287 (2013)
ObjectivesHepatic steatosis is associated with an increased risk of developing serious liver disease and other clinical sequelae of the metabolic syndrome. However, visual estimates of steatosis from histological sections of biopsy samples are subjec
Externí odkaz:
https://doaj.org/article/9dec11ea90504bc8b8f9ae14ecefa295
Publikováno v:
Expert review of endocrinologymetabolism. 4(3)
Hereditary hemochromatosis due to homozygosity for the C282Y mutation in the HFE gene product is the most common autosomal recessive genetic disorder in populations of northern European descent, where it attains a maximum prevalence of approximately
Autor:
Emilia Prakoso, A. Lee, James G. Kench, Janina E.E. Tirnitz-Parker, Z. Kayali, Grant A. Ramm, John K. Olynyk, Nicholas A. Shackel, Andrew D. Clouston, Eng K. Gan, Geoffrey W. McCaughan, David G. Bowen
Publikováno v:
Liver Transplantation. 20:1508-1519
Fibrosis in livers with hepatitis C virus (HCV) recurrence after liver transplantation (LT) can be rapidly progressive, and the mechanisms underlying this process are poorly understood. In livers with HCV infections in the non-LT setting, there is a
Autor:
Sander J. Bangma, Oyekoya T. Ayonrinde, Mervyn Thomas, John K. Olynyk, Timothy G. St. Pierre, Eng K. Gan, Michael J. House, Leon A. Adams
Publikováno v:
Journal of Magnetic Resonance Imaging. 41:322-328
Purpose To investigate the ability of texture analysis of MRI images to stage liver fibrosis. Current noninvasive approaches for detecting liver fibrosis have limitations and cannot yet routinely replace biopsy for diagnosing significant fibrosis. Ma
Autor:
John K. Olynyk, Kevin D. Croft, Anita C. G. Chua, Ross M. Graham, Debbie Trinder, Roheeth D. Delima, Janina E.E. Tirnitz-Parker, Eng K. Gan
Publikováno v:
Hepatology. 56:585-593
Mutations in hemochromatosis protein (HFE) or transferrin receptor 2 (TFR2) cause hereditary hemochromatosis (HH) by impeding production of the liver iron-regulatory hormone, hepcidin (HAMP). This study examined the effects of disruption of Hfe or Tf
Publikováno v:
Pathology. 44:148-152
Hereditary haemochromatosis (HH) is a common autosomal recessive disorder of iron overload in Caucasian populations. Clinical manifestations usually occur in individuals homozygous for the C282Y mutation in the HFE gene product and who have developed
Publikováno v:
Seminars in Liver Disease. 31:293-301
Advances in our knowledge of hereditary hemochromatosis (HH) over the past 150 years have revealed new insights into this common genetic disorder. Meticulous family and HLA association studies followed ultimately by cloning of the HFE gene have drama
Autor:
Alessandra Berzuini, Manoj Kumar, Pathik Parikh, Christophe Corpechot, Mohammad Hassan Murad, Kang Mo Kim, S. Darwish-Murad, L. Caballeria, Javier Crespo, V. de Ledinghen, Salvatore Petta, Seung Up Kim, Patrick S. Kamath, Zhen Wang, J.C. González, Yongpeng Chen, Sofia Carvalhana, Kausik S. Das, M.T. Arias-Loste, Takaaki Sugihara, Eng K. Gan, Fabio Conti, Daniele Prati, Helena Cortez-Pinto, Man-Fung Yuen, Núria Fabrellas, George V. Papatheodoridis, Vincent Wai-Sun Wong, P. Del Poggio, Pere Ginès, Ayman Alsebaey, Shiv Kumar Sarin, Pietro Andreone, Samir Haffar, M.A. Ikram, Fateh Bazerbachi, Norberto C. Chávez-Tapia, Pin Nan Cheng, Kymberly D. Watt, Kazuaki Chayama, Roxana Sirli, Abhijit Chowdhury, John K. Olynyk
Publikováno v:
Gastroenterology. 152:S1106
Autor:
Leon A. Adams, T. G. St. Pierre, Eng K. Gan, Oyekoya T. Ayonrinde, Wenjie Pang, Michael J. House, Prithi S. Bhathal, S. Bangma, John K. Olynyk
Publikováno v:
Journal of Hepatology. 62:S727-S728