Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Enfan Zhang"'
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-26 (2023)
Abstract Multiple myeloma (MM) is an incurable hematological cancer with high spatial- and temporal-heterogeneity. Invasive single-point bone marrow sampling cannot capture the tumor heterogeneity and is difficult to repeat for serial assessments. Li
Externí odkaz:
https://doaj.org/article/acad795dd2d34a3f95146a877c82982b
Autor:
Xi Huang, Wen Cao, Shunnan Yao, Jing Chen, Yang Liu, Jianwei Qu, Yi Li, Xiaoyan Han, Jingsong He, He Huang, Enfan Zhang, Zhen Cai
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-12 (2022)
Abstract Multiple myeloma (MM) remains an incurable plasma cell cancer characterized by abnormal secretion of monoclonal immunoglobulins. The molecular mechanism that regulates the drug sensitivity of MM cells is being intensively studied. Here, we r
Externí odkaz:
https://doaj.org/article/ecd6f5cc86e54cb79176915776c694b1
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-24 (2022)
Abstract RNA demethylase ALKBH5 takes part in the modulation of N6-methyladenosine (m6A) modification and controls various cell processes. ALKBH5-mediated m6A demethylation regulates gene expression by affecting multiple events in RNA metabolism, e.g
Externí odkaz:
https://doaj.org/article/47fb596fe1eb43f5877923e62db89fdf
Autor:
Yi Zhao, Xi Huang, Yujie Zhang, Donghua He, Jingsong He, Enfan Zhang, Miao Chen, Qiuyan Liu, Jing Chen, Zhen Cai
Publikováno v:
Cirugía y Cirujanos, Vol 91, Iss 5 (2023)
Antecedentes: La enfermedad de injerto contra huésped (EICH) es una complicación importante después del trasplante alogénico de células madre hematopoyéticas. Objetivos: Para dilucidar el papel de TLR4, el principal receptor de LPS bacteriano,
Externí odkaz:
https://doaj.org/article/433b23c00d9b4e2e86278e510038881e
Autor:
Qingxiao Chen, Xiaoyan Han, Gaofeng Zheng, Yang Yang, Yi Li, Enfan Zhang, Li Yang, Mengmeng Dong, Donghua He, Jingsong He, Zhen Cai
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundMultiple myeloma is genetically heterogeneous, and chromosome abnormalities play a pivotal role in prognosis. A gain in chromosome 1q (+1q) is among the most common cytogenetic abnormalities; however, its relationship with overall survival
Externí odkaz:
https://doaj.org/article/ad3d07f51c8c4486ae4c29bcc6836b9e
Autor:
Yang Liu, Haimeng Yan, Huiyao Gu, Enfan Zhang, Jingsong He, Wen Cao, Jianwei Qu, Ruyi Xu, Liqin Cao, Donghua He, Jinna Zhang, Yifan Hou, Zhen Cai
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Multiple myeloma (MM) is characterized by an accumulation of monoclonal plasma cells within the bone marrow (BM). Macrophages are an abundant component of myeloma BM microenvironment and support survival of the malignant cells and foster myeloma deve
Externí odkaz:
https://doaj.org/article/3096814808fa48bd96eb3ccae14178d0
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Protopine is an isoquinoline alkaloid that possesses various biological activities including the anti-tumour activity. However, the effects of protopine on liver carcinoma cells are still elusive. The aim of this study is to exami
Externí odkaz:
https://doaj.org/article/ed45d42e59cc44b98dc2c644dea8be03
Autor:
Yunlu Jia, Jianbiao Zhou, Tze King Tan, Tae-Hoon Chung, Regina Wan Ju Wong, Jing-Yuan Chooi, Julia Sze Lynn Lim, Takaomi Sanda, Melissa Ooi, Sanjay De Mel, Cinnie Soekojo, Yongxia Chen, Enfan Zhang, Zhen Cai, Peng Shen, Jian Ruan, Wee-Joo Chng
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 2, Pp 1-13 (2021)
Abstract Multiple myeloma (MM) is an aggressive plasma cell neoplasm characterized by genomic heterogeneity. Superenhancers (SEs) are defined as large clusters of enhancers in close genomic proximity, which regulate genes for maintaining cellular ide
Externí odkaz:
https://doaj.org/article/84a9518ee10c44cc91668e7428907d28
Autor:
Yang Liu, Ruyi Xu, Huiyao Gu, Enfan Zhang, Jianwei Qu, Wen Cao, Xi Huang, Haimeng Yan, Jingsong He, Zhen Cai
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Macrophages are critical mediators of tissue homeostasis, with the function of tissue development and repair, but also in defense against pathogens. Tumor-associated macrophages (TAMs) are considered as the main component in the tumor microe
Externí odkaz:
https://doaj.org/article/bcb8f830adce4c5aa35d2827fd5c2c64
Publikováno v:
Protein & Cell, Vol 11, Iss 12, Pp 881-893 (2020)
Abstract Cytokines are secreted by various cell types and act as critical mediators in many physiological processes, including immune response and tumor progression. Cytokines production is precisely and timely regulated by multiple mechanisms at dif
Externí odkaz:
https://doaj.org/article/bde94e4f3cb74d52a7ae418991acb680