Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Enes K. Ergin"'
Autor:
Amanda C. Lorentzian, Jenna Rever, Enes K. Ergin, Meiyun Guo, Neha M. Akella, Nina Rolf, C. James Lim, Gregor S. D. Reid, Christopher A. Maxwell, Philipp F. Lange
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Childhood acute lymphoblastic leukemia (ALL) genomes show that relapses often arise from subclonal outgrowths. However, the impact of clonal evolution on the actionable proteome and response to targeted therapy is not known. Here, we present
Externí odkaz:
https://doaj.org/article/ef6d2efa7bfe46babb83d0060edfc692
Autor:
Anuli C. Uzozie, Enes K. Ergin, Nina Rolf, Janice Tsui, Amanda Lorentzian, Samuel S. H. Weng, Lorenz Nierves, Theodore G. Smith, C. James Lim, Christopher A. Maxwell, Gregor S. D. Reid, Philipp F. Lange
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Abstract Background Murine xenografts of pediatric leukemia accurately recapitulate genomic aberrations. How this translates to the functional capacity of cells remains unclear. Here, we studied global protein abundance, phosphorylation, and protein
Externí odkaz:
https://doaj.org/article/d322bf218f4945d68e9218ca550e6200
Autor:
Amanda C. Lorentzian, Jenna Rever, Enes K. Ergin, Meiyun Guo, Neha M. Akella, Nina Rolf, C. James Lim, Gregor S.D. Reid, Christopher A. Maxwell, Philipp F. Lange
Childhood acute lymphoblastic leukemia (ALL) genomes show that relapses often arise from subclonal outgrowths. However, the impact of clonal evolution on the actionable proteome and response to targeted therapy is not known. Here, we present a compre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36d959d243dbdd9624a0778a7cce2315
https://doi.org/10.1101/2022.03.04.22271927
https://doi.org/10.1101/2022.03.04.22271927
Publikováno v:
Bioinformatics (Oxford, England). 38(21)
Summary The comprehensive analysis of the proteome and its modulation by post-translational modification (PTM) is increasingly used in biological and biomedical studies. As a result, proteomics data analysis is ever more carried out by scientists wit
Autor:
Nina Rolf, Samuel S.H. Weng, Enes K. Ergin, Gregor S. D. Reid, Christopher A. Maxwell, Philipp F. Lange, Amanda Lorentzian, Anuli Uzozie, Theodore G. Smith, C. James Lim, Janice Tsui, Lorenz Nierves
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-24 (2021)
Background Murine xenografts of pediatric leukemia accurately recapitulate genomic aberrations. How this translates to the functional capacity of cells remains unclear. Here, we studied global protein abundance, phosphorylation, and protein maturatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69953c85c60b541cc99f787081b59071
Autor:
Janice Tsui, Domenic Tuscher, Lorenz Nierves, Enes K. Ergin, Anuli Uzozie, Samuel S.H. Weng, Fatih Demir, Philipp F. Lange, Sabrina Dirnberger, Pitter F. Huesgen
Publikováno v:
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics
Molecular & cellular proteomics 18(11), 2335-2347 (2019). doi:10.1074/mcp.TIR119.001560
Molecular & Cellular Proteomics
Molecular & cellular proteomics 18(11), 2335-2347 (2019). doi:10.1074/mcp.TIR119.001560
Protein N termini reveal fundamental regulatory mechanisms and their perturbation in disease. Regulatory proteolysis is often spatially and temporally confined, thus accessible only in minimal specimen incompatible with established protocols. We deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a781094bfaaafe15f6181c1b8e4fe52
https://doi.org/10.1101/566109
https://doi.org/10.1101/566109