Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Energy Metabolism/genetics"'
Autor:
Ze’ev Hochberg, Kerstin Albertsson-Wikland, Florian Privé, Alina German, Anton Holmgren, Lisa Rubin, Michael Shmoish
Publikováno v:
Hochberg, Z, Albertsson-Wikland, K, Privé, F, German, A, Holmgren, A, Rubin, L & Shmoish, M 2023, ' Energy Trade-off and 4 Extreme Human Body Types ', The Journal of Clinical Endocrinology & Metabolism, vol. 108, no. 5 . https://doi.org/10.1210/clinem/dgac665
Background Resource trade-off theory suggests that increased performance on a given trait comes at the cost of decreased performance on other traits. Methods Growth data from 1889 subjects (996 girls) were used from the GrowUp1974 Gothenburg study. E
Autor:
Janane F. Rahbani, Charlotte Scholtes, Damien M. Lagarde, Mohammed F. Hussain, Anna Roesler, Christien B. Dykstra, Jakub Bunk, Bozena Samborska, Shannon L. O’Brien, Emma Tripp, Alain Pacis, Anthony R. Angueira, Olivia S. Johansen, Jessica Cinkornpumin, Ishtiaque Hossain, Matthew D. Lynes, Yang Zhang, Andrew P. White, William A. Pastor, Maria Chondronikola, Labros Sidossis, Samuel Klein, Anastasia Kralli, Aaron M. Cypess, Steen B. Pedersen, Niels Jessen, Yu-Hua Tseng, Zachary Gerhart-Hines, Patrick Seale, Davide Calebiro, Vincent Giguère, Lawrence Kazak
Publikováno v:
Rahbani, J F, Scholtes, C, Lagarde, D M, Hussain, M F, Roesler, A, Dykstra, C B, Bunk, J, Samborska, B, O’Brien, S L, Tripp, E, Pacis, A, Angueira, A R, Johansen, O S, Cinkornpumin, J, Hossain, I, Lynes, M D, Zhang, Y, White, A P, Pastor, W A, Chondronikola, M, Sidossis, L, Klein, S, Kralli, A, Cypess, A M, Pedersen, S B, Jessen, N, Tseng, Y H, Gerhart-Hines, Z, Seale, P, Calebiro, D, Giguère, V & Kazak, L 2022, ' ADRA1A–Gα q signalling potentiates adipocyte thermogenesis through CKB and TNAP ', Nature Metabolism, vol. 4, no. 11, pp. 1459-1473 . https://doi.org/10.1038/s42255-022-00667-w
Rahbani, J F, Scholtes, C, Lagarde, D M, Hussain, M F, Roesler, A, Dykstra, C B, Bunk, J, Samborska, B, O'Brien, S L, Tripp, E, Pacis, A, Angueira, A R, Johansen, O S, Cinkornpumin, J, Hossain, I, Lynes, M D, Zhang, Y, White, A P, Pastor, W A, Chondronikola, M, Sidossis, L, Klein, S, Kralli, A, Cypess, A M, Pedersen, S B, Jessen, N, Tseng, Y-H, Gerhart-Hines, Z, Seale, P, Calebiro, D, Giguère, V & Kazak, L 2022, ' ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP ', Nature Metabolism, vol. 4, no. 11, pp. 1459-1473 . https://doi.org/10.1038/s42255-022-00667-w
Nature metabolism, vol 4, iss 11
Rahbani, J F, Scholtes, C, Lagarde, D M, Hussain, M F, Roesler, A, Dykstra, C B, Bunk, J, Samborska, B, O'Brien, S L, Tripp, E, Pacis, A, Angueira, A R, Johansen, O S, Cinkornpumin, J, Hossain, I, Lynes, M D, Zhang, Y, White, A P, Pastor, W A, Chondronikola, M, Sidossis, L, Klein, S, Kralli, A, Cypess, A M, Pedersen, S B, Jessen, N, Tseng, Y-H, Gerhart-Hines, Z, Seale, P, Calebiro, D, Giguère, V & Kazak, L 2022, ' ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP ', Nature Metabolism, vol. 4, no. 11, pp. 1459-1473 . https://doi.org/10.1038/s42255-022-00667-w
Nature metabolism, vol 4, iss 11
Noradrenaline (NA) regulates cold-stimulated adipocyte thermogenesis1. Aside from cAMP signalling downstream of β-adrenergic receptor activation, how NA promotes thermogenic output is still not fully understood. Here, we show that coordinated α1-ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75271e3902dba13b05e89b120cc2b7c
https://curis.ku.dk/ws/files/327321080/s42255_022_00667_w.pdf
https://curis.ku.dk/ws/files/327321080/s42255_022_00667_w.pdf
Autor:
Jean-Gael Diserens, Laure Quignodon, Federica Gilardi, Chiara Sardella, Béatrice Desvergne, Barbara Toffoli, Frédéric Preitner, Carine Winkler, Mariano Schiffrin
Publikováno v:
Metabolism, vol. 95, pp. 8-20
The peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-dependent transcription factor involved in many aspects of metabolism, immune response and development. Numerous studies relying on tissue-specific invalidation of the Pparg gene
Autor:
Piaggi, P, Masindova, I, Muller, Yl, Mercader, J, Wiessner, Gb, Chen, P, Sigma Type, 2 Diabetes Consortium, Kobes, S, Hsueh, Wc, Mongalo, M, Knowler, Wc, Krakoff, J, Hanson, Rl, Bogardus, C, Baier, Lj
Publikováno v:
Diabetes
Pima Indians living in Arizona have a high prevalence of obesity, and we have previously shown that a relatively lower energy expenditure (EE) predicts weight and fat mass gain in this population. EE is a familial trait (heritability = 0.52); therefo
Autor:
Luczak, Elizabeth D, Wu, Yuejin, Granger, Jonathan M, Joiner, Mei-Ling A, Wilson, Nicholas R, Gupta, Ashish, Umapathi, Priya, Murphy, Kevin R, Reyes Gaido, Oscar E, Sabet, Amin, Corradini, Eleonora, Tseng, Wen-Wei, Wang, Yibin, Heck, Albert J R, Wei, An-Chi, Weiss, Robert G, Anderson, Mark E, Sub Biomol.Mass Spectrometry & Proteom., Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Communications, 11(1). Nature Publishing Group
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Despite the clear association between myocardial injury, heart failure and depressed myocardial energetics, little is known about upstream signals responsible for remodeling myocardial metabolism after pathological stress. Here, we report increased m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b15221dfae08cf52c633257c1b0eeff
https://dspace.library.uu.nl/handle/1874/411293
https://dspace.library.uu.nl/handle/1874/411293
Publikováno v:
International journal of molecular sciences, vol. 21, no. 8, pp. 2710
Proteoglycans (PGs) are macromolecules present on the cell surface and in the extracellular matrix that confer specific mechanical, biochemical, and physical properties to tissues. Sulfate groups present on glycosaminoglycans, linear polysaccharide c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::a5703ca21ffcd0b6b8c3168a7437f9fe
https://serval.unil.ch/resource/serval:BIB_0257CE41F1A7.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_0257CE41F1A7.P001/REF.pdf
Autor:
Francesca Amati, Enrique Calvo, Sara Cogliati, José Antonio Enríquez, Pablo Hernansanz-Agustín, Nadia Mercader, Carolina García-Poyatos, Jesús Vázquez, Ricardo Magni, Sylviane Lagarrigue, Xavier Langa, Marius Botos
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
EMBO Reports
EMBO reports, vol. 21, no. 7, pp. e50287
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
García-Poyatos, Carolina; Cogliati, Sara; Calvo, Enrique; Hernansanz-Agustín, Pablo; Lagarrigue, Sylviane; Magni, Ricardo; Botos, Marius; Langa, Javier; Amati, Francesca; Vázquez, Jesús; Mercader, Nadia; Enríquez, José Antonio (2020). Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish. EMBO reports, 21(7), e50287. EMBO press 10.15252/embr.202050287
Instituto de Salud Carlos III (ISCIII)
EMBO Reports
EMBO reports, vol. 21, no. 7, pp. e50287
Digibug. Repositorio Institucional de la Universidad de Granada
Consejo Superior de Investigaciones Científicas (CSIC)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
García-Poyatos, Carolina; Cogliati, Sara; Calvo, Enrique; Hernansanz-Agustín, Pablo; Lagarrigue, Sylviane; Magni, Ricardo; Botos, Marius; Langa, Javier; Amati, Francesca; Vázquez, Jesús; Mercader, Nadia; Enríquez, José Antonio (2020). Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish. EMBO reports, 21(7), e50287. EMBO press 10.15252/embr.202050287
The oxidative phosphorylation (OXPHOS) system is a dynamic system in which the respiratory complexes coexist with superassembled quaternary structures called supercomplexes (SCs). The physiological role of SCs is still disputed. Here, we used zebrafi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24773ac5d50874a744edffb1e3d384d
http://hdl.handle.net/20.500.12105/11124
http://hdl.handle.net/20.500.12105/11124
Autor:
Zhuohao Liu, Jin Kui Yang, Kenneth K.Y. Cheng, Philip Hallenborg, Baile Wang, Leigang Jin, Kelvin K.L. Wu, Aimin Xu
Publikováno v:
Liu, Z, Jin, L, Yang, J-K, Wang, B, Wu, K K, Hallenborg, P, Xu, A & Cheng, K K 2018, ' The Dysfunctional MDM2-p53 Axis in Adipocytes Contributes to Ageing Related Metabolic Complications by Induction of Lipodystrophy ', Diabetes, vol. 67, no. 11, pp. 2397-2409 . https://doi.org/10.2337/db18-0684
Profound loss and senescence of adipose tissues are hallmarks of advanced age, but the underlying cause and their metabolic consequences remain obscure. Proper function of the murine double minute 2 (MDM2)–p53 axis is known to prevent tumorigenesis
Autor:
Cécile Aubert, Maithé Tauber, Ronan Roussel, Bénédicte Toussaint, François Pattou, Philippe Froguel, Jean-Michel Borys, Amjad Ghulam, Hélène Loiselle, Mathilde Boissel, Emmanuelle Durand, Sylvia Franc, Julie Kerr-Conte, Julie Maillet, Morgane Baron, Marlène Huyvaert, Amélie Bonnefond, Raphaël Boutry, J. Philippe, Jérémy Thomas, Guillaume Charpentier, Claire Lévy-Marchal, Michel Marre, Mehdi Derhourhi, Aurélie Dechaume, Emmanuel Vaillant, B. Balkau, Stefan Gaget, Raphael Scharfmann, Jacques Weill, Mickaël Canouil
Publikováno v:
Nature Medicine
Nature Medicine, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature medicine
Nature Medicine, Nature Publishing Group, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature Medicine, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
Nature medicine
Nature Medicine, Nature Publishing Group, 2019, 25 (11), pp.1733-1738. ⟨10.1038/s41591-019-0622-0⟩
International audience; The G-protein-coupled receptor accessory protein MRAP2 is implicated in energy control in rodents, notably via the melanocortin-4 receptor1. Although some MRAP2 mutations have been described in people with obesity1-3, their fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e4070864d7e526bb4fbf52762499c4
https://www.hal.inserm.fr/inserm-02439220/document
https://www.hal.inserm.fr/inserm-02439220/document
Publikováno v:
Molecular metabolism
Molecular metabolism, Elsevier, 2019, S2212-8778(19), pp.30921-4. ⟨10.1016/j.molmet.2019.10.002⟩
Molecular Metabolism, Vol 33, Iss, Pp 2-22 (2020)
Molecular metabolism, 2019, S2212-8778(19), pp.30921-4. ⟨10.1016/j.molmet.2019.10.002⟩
Molecular Metabolism
Molecular metabolism, Elsevier, 2019, S2212-8778(19), pp.30921-4. ⟨10.1016/j.molmet.2019.10.002⟩
Molecular Metabolism, Vol 33, Iss, Pp 2-22 (2020)
Molecular metabolism, 2019, S2212-8778(19), pp.30921-4. ⟨10.1016/j.molmet.2019.10.002⟩
Molecular Metabolism
Background The TP53 gene is one of the most commonly inactivated tumor suppressors in human cancers. p53 functions during cancer progression have been linked to a variety of transcriptional and non-transcriptional activities that lead to the tight co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512b296155f99a6f68593209557f69ba
https://www.hal.inserm.fr/inserm-02465175/document
https://www.hal.inserm.fr/inserm-02465175/document