Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Eneko Largo"'
Autor:
Amaia González-Magaña, Jon Altuna, María Queralt-Martín, Eneko Largo, Carmen Velázquez, Itxaso Montánchez, Patricia Bernal, Antonio Alcaraz, David Albesa-Jové
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The Pseudomonas aeruginosa Type 6 secretion effector Tse5 forms pores in the cytoplasmic membrane when ectopically produced and hence has a bacteriolytic effect by depolarising the inner membrane potential.
Externí odkaz:
https://doaj.org/article/e872885286ed4aada2170b6ac66c35a5
Autor:
Edurne Rujas, Daniel P. Leaman, Sara Insausti, Pablo Carravilla, Miguel García-Porras, Eneko Largo, Izaskun Morillo, Rubén Sánchez-Eugenia, Lei Zhang, Hong Cui, Ibon Iloro, Félix Elortza, Jean-Philippe Julien, Christian Eggeling, Michael B. Zwick, Jose M.M. Caaveiro, José L. Nieva
Publikováno v:
iScience, Vol 24, Iss 9, Pp 102987- (2021)
Summary: Broadly neutralizing antibodies (bnAbs) against HIV-1 are frequently associated with the presence of autoreactivity/polyreactivity, a property that can limit their use as therapeutic agents. The bnAb 4E10, targeting the conserved Membrane pr
Externí odkaz:
https://doaj.org/article/f69c2aef00f544b7909cd6e9049a9b2c
Autor:
Pablo Carravilla, Jakub Chojnacki, Edurne Rujas, Sara Insausti, Eneko Largo, Dominic Waithe, Beatriz Apellaniz, Taylor Sicard, Jean-Philippe Julien, Christian Eggeling, José L. Nieva
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights
Externí odkaz:
https://doaj.org/article/32282e6593b04122a0dc319b89d08e3e
Autor:
David González-Bullón, Kepa B. Uribe, Eneko Largo, Garazi Guembelzu, Aritz B. García-Arribas, César Martín, Helena Ostolaza
Publikováno v:
Biomolecules, Vol 9, Iss 5, p 183 (2019)
RTX (Repeats in ToXin) pore-forming toxins constitute an expanding family of exoproteins secreted by many Gram-negative bacteria and involved in infectious diseases caused by said pathogens. Despite the relevance in the host/pathogen interactions, th
Externí odkaz:
https://doaj.org/article/899d877d3b68485f9e7c916fd1fc43d8
Autor:
Douglas P. Gladue, Eneko Largo, Lauren G. Holinka, Elizabeth Ramirez-Medina, Elizabeth A. Vuono, Keith A. Berggren, Guillermo R. Risatti, Jose L. Nieva, Manuel V. Borca
Publikováno v:
Viruses, Vol 10, Iss 9, p 460 (2018)
We have previously shown that Classical Swine Fever Virus (CSFV) p7 is an essential nonstructural protein with a viroporin activity, a critical function in the progression of virus infection. We also identified p7 domains and amino acid residues crit
Externí odkaz:
https://doaj.org/article/0224ea974d694f75b6761246635b39d0
Autor:
Douglas P. Gladue, Lidia Gomez-Lucas, Eneko Largo, Lauro Velazquez-Salinas, Elizabeth Ramirez-Medina, Johana Torralba, Maria Queralt, Antonio Alcaraz, Jose L. Nieva, Manuel V. Borca
Publikováno v:
Journal of Virology.
ASFV is responsible for an extensively distributed pandemic causing important economic losses in the pork industry in Eurasia. The development of countermeasures is partially limited by the insufficient knowledge regarding the function of the majorit
Autor:
Jon Altuna, Antonio Alcaraz, David Albesa-Jové, Eneko Largo, María Queralt-Martín, Itxaso Montánchez, Amaia González-Magaña
The Type VI Secretion System (T6SS) of Pseudomonas aeruginosa injects effector proteins into neighbouring competitors and host cells, providing a fitness advantage that allows this opportunistic nosocomial pathogen to persist and prevail during the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::006cae534a0bdd284318e8c041bbbfb4
https://doi.org/10.21203/rs.3.rs-967174/v1
https://doi.org/10.21203/rs.3.rs-967174/v1
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands)
Repositori Universitat Jaume I
Universitat Jaume I
Repositori Universitat Jaume I
Universitat Jaume I
Classic swine fever is a highly contagious and often fatal viral disease that is caused by the classical swine fever virus (CSFV). Protein p7 of CFSV is a prototype of viroporin, a family of small, highly hydrophobic proteins postulated to modulate v
Autor:
Johana Torralba, Igor de la Arada, Pablo Carravilla, Eneko Largo, José L. Nieva, Edurne Rujas, Christian Eggeling, José Luis R. Arrondo, Sara Insausti, Beatriz Apellaniz
Publikováno v:
ACS infectious diseases. 6(8)
The envelope glycoprotein (Env) enables HIV-1 cell entry through fusion of host-cell and viral membranes induced by the transmembrane subunit gp41. Antibodies targeting the C-terminal sequence of the membrane-proximal external region (C-MPER) block t
Autor:
Manuel V. Borca, Eneko Largo, Johana Torralba, Vicente M. Aguilella, Douglas P. Gladue, Antonio Alcaraz, José L. Nieva
Publikováno v:
Repositori Universitat Jaume I
Universitat Jaume I
Universitat Jaume I
Permeabilization of the Endoplasmic Reticulum (ER) is instrumental in the progression of host-cell infection by many viral pathogens. We have described that permeabilization of ER model membranes by the pore-forming domain of the Classical Swine Feve