Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ene Ustav"'
Autor:
Lisett Liblekas, Alla Piirsoo, Annika Laanemets, Eva-Maria Tombak, Airiin Laaneväli, Ene Ustav, Mart Ustav, Marko Piirsoo
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The life-cycle of human papillomaviruses (HPVs) includes three distinct phases of the viral genome replication. First, the viral genome is amplified in the infected cells, and this amplification is often accompanied by the oligomerization of the vira
Externí odkaz:
https://doaj.org/article/169b0f81cf974ff49b3e8f88487d78ea
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211235 (2019)
Due to the extreme tissue and species restriction of the papillomaviruses (PVs), there is a great need for animal models that accurately mimic PV infection in humans for testing therapeutic strategies against human papillomaviruses (HPVs). In this st
Externí odkaz:
https://doaj.org/article/4f2eacc2717e492099d6f745459f51a0
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224334 (2019)
The replication of human papillomavirus (HPV) genomes requires E1 and E2 proteins as the viral trans-factors and the replication origin, located in the URR, as a cis-element. The minimal requirements for an HPV replication origin vary among different
Externí odkaz:
https://doaj.org/article/5ea0a9324c034168b96dae5241f8a1ff
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006168 (2017)
Human papillomaviruses (HPVs) are oncogenic viruses that cause numerous different cancers as well as benign lesions in the epithelia. To date, there is no effective cure for an ongoing HPV infection. Here, we describe the generation process of a plat
Externí odkaz:
https://doaj.org/article/26a81ea166554808a3fb7710450b6b5d
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116151 (2014)
The human osteosarcoma cell line U2OS is useful for studying genome replication of human papillomavirus (HPVs) subtypes that belong to different phylogenetic genera. In this study, we defined the HPV18 transcription map in U2OS cells during transient
Externí odkaz:
https://doaj.org/article/57f37df24acc4759a541a2e8f9ff71e6
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000397 (2009)
In HPV-related cancers, the "high-risk" human papillomaviruses (HPVs) are frequently found integrated into the cellular genome. The integrated subgenomic HPV fragments express viral oncoproteins and carry an origin of DNA replication that is capable
Externí odkaz:
https://doaj.org/article/ed683847efa04d3db10ebc234d9ff25f
Autor:
Annika Laanemets, Mart Ustav, Lisett Liblekas, Marko Piirsoo, Eva-Maria Tombak, Alla Piirsoo, Ene Ustav, Airiin Laaneväli
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
The life-cycle of human papillomaviruses (HPVs) includes three distinct phases of the viral genome replication. First, the viral genome is amplified in the infected cells, and this amplification is often accompanied by the oligomerization of the vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1052cedc071016a5da2b98257523c9a2
https://doi.org/10.3389/fmicb.2021.738125
https://doi.org/10.3389/fmicb.2021.738125
E2 protein is the major determinant of specificity at the human papillomavirus origin of replication
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0224334 (2019)
PLoS ONE, Vol 14, Iss 10, p e0224334 (2019)
The replication of human papillomavirus (HPV) genomes requires E1 and E2 proteins as the viral trans-factors and the replication origin, located in the URR, as a cis-element. The minimal requirements for an HPV replication origin vary among different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fec95c86af7a541eec0e67302a4eb1fb
https://pubmed.ncbi.nlm.nih.gov/31644607
https://pubmed.ncbi.nlm.nih.gov/31644607
Publikováno v:
Current Protocols in Microbiology
This unit includes the necessary information to conduct neutral/neutral and neutral/alkaline two-dimensional and neutral/neutral/alkaline three-dimensional agarose gel electrophoresis. The methodology has been optimized over the years to gain a bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1436be99e481cac128e437be5da1f7c
https://doi.org/10.1002/cpmc.28
https://doi.org/10.1002/cpmc.28
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 1, p e0211235 (2019)
PLoS ONE, Vol 14, Iss 1, p e0211235 (2019)
Due to the extreme tissue and species restriction of the papillomaviruses (PVs), there is a great need for animal models that accurately mimic PV infection in humans for testing therapeutic strategies against human papillomaviruses (HPVs). In this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c6eac268b012a1a24d7b265e0db7af
https://doi.org/10.1371/journal.pone.0211235
https://doi.org/10.1371/journal.pone.0211235