Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Endre Laczko"'
Autor:
Lucas Caldi Gomes, Sonja Hänzelmann, Fabian Hausmann, Robin Khatri, Sergio Oller, Mojan Parvaz, Laura Tzeplaeff, Laura Pasetto, Marie Gebelin, Melanie Ebbing, Constantin Holzapfel, Stefano Fabrizio Columbro, Serena Scozzari, Johanna Knöferle, Isabell Cordts, Antonia F. Demleitner, Marcus Deschauer, Claudia Dufke, Marc Sturm, Qihui Zhou, Pavol Zelina, Emma Sudria-Lopez, Tobias B. Haack, Sebastian Streb, Magdalena Kuzma-Kozakiewicz, Dieter Edbauer, R. Jeroen Pasterkamp, Endre Laczko, Hubert Rehrauer, Ralph Schlapbach, Christine Carapito, Valentina Bonetto, Stefan Bonn, Paul Lingor
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a debilitating motor neuron disease and lacks effective disease-modifying treatments. This study utilizes a comprehensive multiomic approach to investigate the early and sex-specific molecular mechanism
Externí odkaz:
https://doaj.org/article/a01f4f133f534a40923cc24277e82506
Autor:
Marine Berquez, Zhiyong Chen, Beatrice Paola Festa, Patrick Krohn, Svenja Aline Keller, Silvia Parolo, Mikhail Korzinkin, Anna Gaponova, Endre Laczko, Enrico Domenici, Olivier Devuyst, Alessandro Luciani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Differentiation is critical for cell fate decisions, but the signals involved remain unclear. The kidney proximal tubule (PT) cells reabsorb disulphide-rich proteins through endocytosis, generating cystine via lysosomal proteolysis. Here we
Externí odkaz:
https://doaj.org/article/11a5f48d3b2345418cf8893bc3e0feb9
Autor:
Dina Neves, Andreia Figueiredo, Marisa Maia, Endre Laczko, Maria Salomé Pais, Alfredo Cravador
Publikováno v:
Plants, Vol 12, Iss 10, p 1929 (2023)
Phlomis purpurea grows spontaneously in the southern Iberian Peninsula, namely in cork oak (Quercus suber) forests. In a previous transcriptome analysis, we reported on its immunity against Phytophthora cinnamomi. However, little is known about the i
Externí odkaz:
https://doaj.org/article/f0fe6055d5c949cf9cdeb9fffad1d2ed
Autor:
Jasmin Walter, Fabian Huwiler, Claudia Fortes, Jonas Grossmann, Bernd Roschitzki, Junmin Hu, Hanspeter Naegeli, Endre Laczko, Ulrich Bleul
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-24 (2019)
Abstract Background Maturation of oocytes under in vitro conditions (IVM) results in impaired developmental competence compared to oocytes matured in vivo. As oocytes are closely coupled to their cumulus complex, elucidating aberrations in cumulus me
Externí odkaz:
https://doaj.org/article/07c2e13c297549548163b0dc5c482f64
Autor:
Benjamin V. Ineichen, Serena Di Palma, Endre Laczko, Shane A. Liddelow, Susanne Neumann, Martin E. Schwab, Alice C. Mosberger
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Regulating gene expression at the protein level is becoming increasingly important for answering basic questions in neurobiology. Several techniques using destabilizing domains (DD) on transgenes, which can be activated or deactivated by specific dru
Externí odkaz:
https://doaj.org/article/eb5f396269ce448e88e0423add2a6600
Autor:
Paola Valdivieso, David Vaughan, Endre Laczko, Michael Brogioli, Sarah Waldron, Jörn Rittweger, Martin Flück
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
The insertion/deletion polymorphism in the gene for the regulator of vascular tone, angiotensin-converting enzyme (ACE), is the prototype of a genetic influence on physical fitness and this involves an influence on capillary supply lines and dependen
Externí odkaz:
https://doaj.org/article/2b909142b2904318bc050fe9244acb80
Autor:
David Vaughan, Michael Brogioli, Thomas Maier, Andy White, Sarah Waldron, Jörn Rittweger, Marco Toigo, Jessica Wettstein, Endre Laczko, Martin Flück
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149046 (2016)
OBJECTIVE:A silencer region (I-allele) within intron 16 of the gene for the regulator of vascular perfusion, angiotensin-converting enzyme (ACE), is implicated in phenotypic variation of aerobic fitness and the development of type II diabetes. We hyp
Externí odkaz:
https://doaj.org/article/47c7523aa48e429e84f9b7a24a13ece2
Autor:
Sandra Goetze, Ermir Qeli, Christian Mosimann, An Staes, Bertran Gerrits, Bernd Roschitzki, Sonali Mohanty, Eva M Niederer, Endre Laczko, Evy Timmerman, Vinzenz Lange, Ernst Hafen, Ruedi Aebersold, Joël Vandekerckhove, Konrad Basler, Christian H Ahrens, Kris Gevaert, Erich Brunner
Publikováno v:
PLoS Biology, Vol 7, Iss 11, p e1000236 (2009)
Protein modifications play a major role for most biological processes in living organisms. Amino-terminal acetylation of proteins is a common modification found throughout the tree of life: the N-terminus of a nascent polypeptide chain becomes co-tra
Externí odkaz:
https://doaj.org/article/175db257c04e4d4988c704d7722b31b6
Autor:
Colucci, Manuel, Zumerle, Sara, Bressan, Silvia, Gianfanti, Federico, Troiani, Martina, Valdata, Aurora, D’Ambrosio, Mariantonietta, Pasquini, Emiliano, Varesi, Angelica, Cogo, Francesca, Mosole, Simone, Dongilli, Cristina, Desbats, Maria Andrea, Contu, Liliana, Revankdar, Ajinkya, Chen, Jingjing, Kalathur, Madhuri, Perciato, Maria Luna, Basilotta, Rossella, Endre, Laczko, Schauer, Stefan, Othman, Alaa, Guccini, Ilaria, Saponaro, Miriam, Maraccani, Luisa, Bancaro, Nicolò, Lai, Ping, Liu, Lei, Pernigoni, Nicolò, Mele, Federico, Merler, Sara, Trotman, Lloyd C., Guarda, Greta, Calì, Bianca, Montopoli, Monica, Alimonti, Andrea
Publikováno v:
In Cancer Cell 8 April 2024 42(4):646-661
Readily accessible diagnostic tools are crucial for early detection of Alzheimer’s disease (AD). Here, we sought to identify peripheral metabolism biomarkers of cerebral AD pathology. Untargeted liquid chromatography-mass spectrometry was used to q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::442b1be18450959bbd52d9c80927dcdb
https://doi.org/10.21203/rs.3.rs-2786133/v1
https://doi.org/10.21203/rs.3.rs-2786133/v1